| With radioligand binding assay , we studied the central benzodiazepine receptors ( CBR ) in the different regions of brain including the telencephalon , diencephalon , brain stem and cerebellum in a rat model of hepatic encephalopathy ( HE ) induced by partial hepatectomy following carbon tetrachloride ( CC 1 ( 4 ) ) intoxication and in the controls . ^^^ The results support the recent suggestion that the alterations of CBR play a significant role in the pathogenesis of HE . ^^^ Among the ranges of the alterations of CBR in the HE rats , the telencephalon ranked first , the brain stem second , the cerebellum third , and the diencephalon last . . ^^^ |