| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| Binding of T lymphoblastoid cells to thymic epithelial cells was inhibited by antibody to galectin 1 on the epithelial cells , and by two antibodies , T 305 and 2B11 , that recognize carbohydrate epitopes on the T cell surface glycoproteins CD 43 and CD 45 , respectively . ^^^ Preferential binding of galectin 1 to immature thymocytes may result from regulated expression of preferred oligosaccharide ligands on those cells , since we found that the epitope recognized by the T 305 antibody , the core 2 O glycan structure on CD 43 , was expressed on cortical , but not medullary cells . ^^^ |
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| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| We have determined that galectin 1 binds to a restricted set of T cell surface glycoproteins , and that only CD 45 , CD 43 , and CD 7 appear to directly participate in galectin 1 induced apoptosis . ^^^ To determine whether these specific glycoproteins interact cooperatively or independently to deliver the galectin 1 death signal , we examined the cell surface localization of CD 45 , CD 43 , CD 7 , and CD 3 after galectin 1 binding to human T cell lines and human thymocytes . ^^^ |
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| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| Galectin 1 binds to T cell surface glycoproteins CD 45 , CD 43 , and CD 7 , although the precise roles of each receptor in cell death are unknown . ^^^ |
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| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| Several galectin 1 receptors are discussed such as CD 45 , CD 7 , CD 43 , CD 2 , CD 3 , CD 4 , CD 107 , CEA , actin , extracellular matrix proteins such as laminin and fibronectin , glycosaminoglycans , integrins , a beta lactosamine glycolipid , GM 1 ganglioside , polypeptide HBGp 82 , glycoprotein 90 K / MAC 2BP , CA 125 cancer antigen , and pre B cell receptor . . ^^^ |
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| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| T cells bound to galectin 1 coated matrix demonstrated enhanced clustering of CD 43 , including at the T cell : matrix interface , compared to CD 43 on T cells bound to matrix in the absence of galectin 1 . ^^^ As translocation of CD 43 to the trailing edge is essential for polarized T cell migration , these data indicate that galectin 1 mediated clustering of CD 43 contributes to the inhibitory effect on T cell migration . ^^^ |
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| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| We implement our CCCP algorithms on two and three dimensional spin glasses and compare their results to BP and GBP . ^^^ |
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| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.63299389 |
| Galectin 1 , a beta galactoside binding protein that can occur as both a monomer and a homodimer , binds to leucocyte membrane antigens such as CD 7 , CD 43 , and CD 45 , and has immune regulatory functions in several animal models of autoimmune disease . 0.63299389^^^ |
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| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P16150 and P09382 |
Pubmed |
SVM Score :0.0 |
| NA |
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