| Interacting proteins: Q10472 and P15941 |
Pubmed |
SVM Score :0.0 |
| GalNAc T 4 transferred GalNAc to two sites in the MUC 1 tandem repeat sequence ( Ser in GVTSA and Thr in PDTR ) using a 24 mer glycopeptide with GalNAc residues attached at sites utilized by GalNAc T 1 , T 2 , and T 3 ( TAPPAHGVTSAPDTRPAPGSTAPPA , GalNAc attachment sites underlined ) . ^^^ |
|
| Interacting proteins: Q10472 and P15941 |
Pubmed |
SVM Score :0.0 |
| The peptide contains both the GVTSAP sequence , which is an effective substrate for GalNAc T 1 and T 3 transferases , and the PDTRP fragment , which is a well known immunodominant epitope recognized by several anti MUC 1 monoclonal antibodies . ^^^ |
|
| Interacting proteins: Q10472 and P15941 |
Pubmed |
SVM Score :0.0 |
| Evidence from in vitro glycosylation with polypeptide N acetylgalactosaminyltransferases GalNAc T 1 and GalNAc T 2 in concert with mass spectrometric analyses of in vivo glycosylated MUC 1 probes from transiently transfected HEK 293 cells indicated reduced glycosylation densities of repeats with three concerted replacements : AHGVTSAPESRPAPGSTAPA . ^^^ |
|
| Interacting proteins: Q10472 and P15941 |
Pubmed |
SVM Score :0.0 |
| In this report , ( 15 ) N and ( 13 ) C labeled forms of a recombinant MUC 1 construct containing five tandem repeats were used as substrates to define the order and kinetics of addition of N acetylgalactosamine ( GalNAc ) moieties by a recombinant active form of the human enzyme UDP GalNAc : polypeptide N acetylgalactosaminyltransferase 1 ( ppGalNAc T 1 ; residues 40 559 ) . ^^^ |
|
| Interacting proteins: Q10472 and P15941 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q10472 and P15941 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q10472 and P15941 |
Pubmed |
SVM Score :0.0 |
| NA |
|