Interacting proteins: P15941 and P62993 |
Pubmed |
SVM Score :0.0 |
It has been shown previously that the MUC 1 cytoplasmic domain interacts with the SH 2 domain containing GRB 2 protein , which transduces signals to ras , a protein which in its activated form can lead to cell transformation . ^^^ |
|
Interacting proteins: P15941 and P62993 |
Pubmed |
SVM Score :0.0 |
Moreover , a series of recent studies has shown that the highly conserved cytoplasmic tail of MUC 1 interacts specifically with a series of important signal transducing molecules including beta catenin , Grb 2 and erbB family members . ^^^ |
|
Interacting proteins: P15941 and P62993 |
Pubmed |
SVM Score :0.0 |
In a previous study , we showed that the cytoplasmic YXXphi motif Y20HPM and the tyrosine phosphorylated Y60TNP motif are required for MUC 1 clathrin mediated endocytosis through binding AP 2 and Grb 2 , respectively ( Kinlough , C . ^^^ |
|
Interacting proteins: P15941 and P62993 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15941 and P62993 |
Pubmed |
SVM Score :0.0 |
NA |
|