| We also show that expression of MUC 1 with a mutation at Tyr 60 ( 1 ) disrupts the interaction between MUC 1 and c Abl , ( 2 ) relieves the MUC 1 induced block of c Abl phosphorylation on Thr 735 and binding to 14 3 3 , and ( 3 ) attenuates the MUC 1 antiapoptotic function . 0.64976422^^^ The results demonstrate that c Abl phosphorylates MUC 1 on Tyr 60 and forms a complex with MUC 1 by binding of the c Abl SH 2 domain to the pTyr 60 site . 0.64433975^^^ |