| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| Moreover , VSGP / F spondin inhibited the activation of Akt when HUVECs on vitronectin were stimulated with VEGF . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| In previous work , we found that VEGF bound specifically to fibronectin ( Fn ) but not vitronectin or collagens . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| VEGFR 2 phosphorylation and mitogenicity induced by VEGF A 165 were enhanced in cells plated on the alphavbeta 3 ligand , vitronectin , compared with cells plated on the alpha5beta1 ligand , fibronectin or the alpha2beta1 ligand , collagen . ^^^ BV 4 anti beta 3 integrin mAb , which does not interfere with endothelial cell adhesion to vitronectin , reduced ( 1 ) the tyrosine phosphorylation of VEGFR 2 ; ( 2 ) the activation of downstream transductor phosphoinositide 3 OH kinase ; and ( 3 ) biological effects triggered by VEGF A 165 . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| Addition of soluble vitronectin , or fibrinogen to RPE cell cultures resulted in a small to moderate increase in VEGF and FGF 2 in the media , while each of these growth factors was dramatically increased after addition of thrombospondin 1 ( TSP 1 ) . ^^^ RPE cells grown on TSP 1 coated plates showed increased VEGF and FGF 2 in their media compared to cells grown on plates coated with type 4 collagen , laminin , vitronectin , or fibronectin . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| Among many of its KS promoting activities , the Tat protein augments the angiogenic activities of basic fibroblast growth factor ( bFGF ) , interferon gamma , and vascular endothelial growth factor ( VEGF ) ; it also mimics the effects of the extramedullary matrix proteins fibronectin and vitronectin , and increases the expression of matrix metalloproteinases . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| However , it does induce chemotaxis , trans Matrigel migration , and secretion of matrix metalloproteinase 9 ( MMP 9 ) and vascular endothelial growth factor ( VEGF ) by these cells , and both SDF 1 and TPO increase the adhesion of alpha ( IIb ) beta ( 3 ) ( + ) cells to fibrinogen and vitronectin . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| Endothelial cell migration stimulated by VEGF ( 121 ) was potentiated by vitronectin to a greater extent than that stimulated by VEGF ( 165 ) . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| Endothelial cell haptotaxis was stimulated by constitutively active V12Rac on collagen and vitronectin coated supports , and chemotaxis was further stimulated by VEGF . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| In this study , we found that addition of VEGF to human umbilical vein endothelial cells cultivated on vitronectin triggers a synergistic interaction between the VEGF receptor VEGFR 2 and the clustered integrin receptor alphavbeta 3 . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| The results show that thalidomide inhibits endotelial cell proliferation induced by bFGF and VEGF , more so if the cells are grown on vitronectin ; moreover , treatment with thalidomide reduces the release of MMP 2 and IL 8 by endothelial cells , suggesting a further pathway for the antiangiogenic activity of drug . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| RESULTS : As judged by positive staining for endothelial markers vWF and VE cadherin , the combination of VEGF with fibronectin ( FN ) produced significantly more endothelial colonies ( P < . 05 ) than did collagens 1 or 4 or vitronectin . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| Additionally , in a modified Boyden chamber assay , migration of HUVECs in response to VEGF was significantly affected following transduction of either Ad shTeM or Ad shChM 1 and these transduced HUVECs were found to spread well on type 1 collagen or fibronectin , but not on vitronectin . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| Alpha5beta1 mediated endothelial cell adhesion and migration to FN , both under control conditions and under stimulation by vascular endothelial growth factor ( VEGF ) , were inhibited specifically and in a dose dependent manner by HNPs , whereas endothelial cell adhesion and migration to other components of the extracellular matrix , such as vitronectin , collagen , or fibrinogen / fibrin were not . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| We observed that growth on vitronectin or fibronectin impaired the ability of endostatin to inhibit VEGF induced HDMEC proliferation to the greatest extent as determined by BrdU incorporation . ^^^ Interestingly , endostatin inhibited VEGF induced HDMEC migration following culture on collagen 1 , collagen 4 and laminin , while migration was not inhibited by endostatin following HDMEC culture on other matrices including vitronectin , fibronectin and tenascin C . ^^^ |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15692 and P04004 |
Pubmed |
SVM Score :0.0 |
| NA |
|