| Interacting proteins: Q9UQ88 and P15291 |
Pubmed |
SVM Score :0.71036974 |
| In this study , the p58GTA interaction with beta 1 , 4 GT 1 was confirmed using an in vitro assay with the TNT Coupled Reticulocyte Lysate System . 0.71036974^^^ |
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| Interacting proteins: Q9UQ88 and P15291 |
Pubmed |
SVM Score :0.0 |
| Downregulation of beta 1 , 4 galactosyltransferase 1 inhibits CDK 11 ( p 58 ) mediated apoptosis induced by cycloheximide . ^^^ Some evidences suggested beta 1 , 4 galactosyltransferase 1 ( beta 1 , 4 GT 1 ) might participate in apoptosis induced by CDK 11 ( p 58 ) . ^^^ In this study , we demonstrated that ectopically expressed beta 1 , 4 GT 1 increased CDK 11 ( p 58 ) mediated apoptosis induced by cycloheximide ( CHX ) . ^^^ In contrast , RNAi mediated knockdown of beta 1 , 4 GT 1 effectively inhibited apoptosis induced by CHX in CDK 11 ( p 58 ) overexpressing cells . ^^^ We proposed that beta 1 , 4 GT 1 might contribute to the pro apoptotic effect of CDK 11 ( p 58 ) . ^^^ |
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| Interacting proteins: Q9UQ88 and P15291 |
Pubmed |
SVM Score :0.0 |
| Furthermore , kinase activity of p 58 ( PITSLRE ) was found to increase greatly in the presence of cyclin D 3 using a specific substrate , beta 1 , 4 galactosyltransferase 1 . ^^^ |
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