| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| Another neonatal onset patient showed normal synthesis of beta ETF but decreased synthesis of alpha ETF . ^^^ Radiolabeling and immunoprecipitation studies revealed that three of the six neonatal onset GA 2 patients had greatly diminished or absent alpha and beta ETF subunits , consistent with a failure to assemble a stable heterodimer . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| ETF is a mitochondrial flavoprotein consisting of an alpha subunit , alpha ETF , and a beta subunit , beta ETF . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| Both alpha ( alpha ETF , 32 , 000 molecular weight [ mol wt ] ) and beta subunits ( beta ETF , 27 , 000 mol wt ) were nuclear coded , and synthesized in the cytosol . alpha ETF was synthesized as a precursor ( p alpha ETF ) , 3 , 000 mol wt larger than its mature counterpart , and was translocated into the mitochondria and processed to the mature alpha ETF . ^^^ Among six glutaric aciduria type 2 ( GAII ) and two ethylmalonic adipic aciduria cell lines , defective p alpha ETF synthesis was observed in three GAII cell lines , and beta ETF synthesis was normal . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| Assignment of Etfdh , Etfb , and Etfa to chromosomes 3 , 7 , and 13 : the mouse homologs of genes responsible for glutaric acidemia type 2 in human . ^^^ We used cDNA probes for the Etfdh , Etfb , and Etfa genes to determine localization of these mouse genes to chromosomes 3 , 7 , and 13 . . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| Three open reading frames ( bcd , etfB , and etfA ) are located between crt and hbd . ^^^ Open reading frames etfB and etfA , located downstream of bcd , encode 27 . 2 and 36 . 1 kDa proteins , respectively , and show homology with the fixAB genes and the alpha and beta subunits of the electron transfer flavoprotein . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| We report the genomic structures of the ETFA , ETFB , and ETFDH genes and the identification and characterization of seven novel and three previously reported disease causing mutations . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| In this work , we show that Saccharomyces cerevisiae frataxin orthologue Yfh1p interacts physically with succinate dehydrogenase complex subunits Sdh1p and Sdh2p of the yeast mitochondrial electron transport chain and also with electron transfer flavoprotein complex ETFalpha and ETFbeta subunits from the electron transfer flavoprotein complex . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| In a type 1 strain ( ATCC 19171 ( T ) ) , the genes coding for the enzymes that catalyze the conversion from acetyl CoA to butyryl CoA , thl ( thiolase ) , crt ( crotonase ) , hbd ( beta hydroxybutyryl CoA dehydrogenase ) , bcd ( butyryl CoA dehydrogenase ) , etfB ( electron transfer flavoprotein [ ETF ] beta ) , and etfA ( ETF alpha ) , were found to be clustered and arranged in this order . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| ETF is a mitochondrial matrix protein consisting of alpha ( 30kDa ) and beta ( 28kDa ) subunits encoded by the ETFA and ETFB genes , respectively . ^^^ The majority of patients had mutations in the ETFA gene while only two of them harboured mutations in the ETFB gene . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| GAII is caused by defects in intra mitochondrial acyl CoA dehydrogenation due to deficiency in one of three molecules : the alpha or beta subunits of the electron transport flavoprotein ( ETFA ; OMIM 231680 , ETFB ; OMIM 130410 ) , or ETF dehydrogenase ( ETFDH ; OMIM 231675 ) . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| Yeast two hybrid experiments showed that the Arabidopsis ETFalpha and ETFbeta can form a heteromeric protein . ^^^ |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P38117 and P13804 |
Pubmed |
SVM Score :0.0 |
| NA |
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