| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| The first enzyme in the pathway delta aminolevulinic acid synthase ( ALAS ) is targeted to the mitochondrion , but the next two enzymes porphobilinogen synthase ( PBGS ) and hydroxymethylbilane synthase ( HMBS ) are targeted to the plastid . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| The Bacillus subtilis genes hemB , hemC and hemD , encoding respectively the enzymes porphobilinogen synthase , hydroxymethylbilane synthase and uroporphyrinogen 3 synthase , have been expressed in Escherichia coli using a single plasmid construct . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Delta aminolevulinic acid dehydratase ( ALA D ) and porphobilinogen deaminase ( PBG D ) activities in blood were significantly elevated in the pregnant untreated ( Con pregnant ) group , compared to the nonpregnant mice untreated ( Con nonpregnant ) and nonpregnant mice treated with Be ( Be nonpregnant ) groups . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Protein structure alterations induced by porphyrins with different physico chemical properties on delta aminolevulinic acid dehydratase ( ALA D ) and porphobilinogen deaminase ( PBG D ) were examined . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Chick embryos of 7 , 9 , 11 , 12 , 13 , 14 , 15 , 17 and 19 d of embryonic development were examined to determine the activities of 5 aminolevulinic dehydratase ( ALA D , EC 4 . 2 . 1 . 24 ) and porphobilinogen deaminase ( PBG D , EC 4 . 3 . 1 . 8 ) . 2 . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| In an attempt to identify rate limiting steps in heme synthesis , which may constitute potential regulatory points , we constructed yeast strains overproducing two enzymes of the pathway : the porphobilinogen synthase ( PBG S ) and deaminase ( PBG D ) . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| As it has been suggested that uremic toxins ( middle molecules ) play an important role in the mechanism of anemia , we studied the activities of three heme synthesizing enzymes : delta aminolevulinic acid dehydratase , porphobilinogen deaminase and ferrochelatase . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| During the first three days of regeneration the weights of livers of one third and two third hepatectomized rats increased 1 . 5 fold and 2 . 7 fold and the activity of porphobilinogen deaminase increased 2 fold and 4 fold and was inversely correlated with ferrochelatase activity . delta Aminolevulinic acid synthase and delta aminolevulinic acid dehydratase activities were reduced . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| The subcellular location of the two porphyrin synthesis enzymes 5 aminolaevulinate dehydratase ( ALAD ) and porphobilinogen deaminase ( PBGD ) was investigated in Pisum sativum ( pea ) leaves and spadices of Arum ( cuckoo pint ) . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| In contrast to the effects on ALAD , DMSO decreases the activities of porphobilinogen deaminase and uroporphyrinogen decarboxylase . . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Low levels of delta aminolevulinic acid dehydratase , porphobilinogen deaminase and uroporphyrinogen decarboxylase activities , and heme concentrations were found in the extract of the parasite walls and scolex , but not in the vesicular fluid . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Porphorbilinogen oxygenase ( EC 4 . 2 . 1 . 24 ) was associated with the microsomal fraction of bone marrow in normal rats and in rats submitted to erythropoietic stress , while porphobilinogen deaminase ( EC 4 . 3 . 1 . 8 ) of the same origin was present in the cytosol . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| The activities of delta aminolevulinic acid synthase , gamma , delta dioxovaleric acid transaminase , delta aminolevulinic acid dehydratase , and ferrochelatase were not affected significantly by treatment of suppressed marrow cells with erythropoietin over a period of 4 days , whereas that of porphobilinogen deaminase was increased by as much as 3 . 5 fold by the 3rd day of incubation . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Some alterations in the protein structure of delta aminolevulinic acid dehydratase ( ALA D ) and porphobilinogen deaminase ( PBG D ) induced by uroporphyrin ( URO ) and prototoporphyrin ( PROTO ) have been observed previously . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| MATERIALS AMD METHODS : delta aminolevulinic acid dehydratase ( ALA D ) and porphobilinogen deaminase ( PBG D ) partially purified from bovine liver , were exposed to 10 microM uroporphyrin ( Uro ) , phyriaporphyrin ( Phyria ) , hexaporphyrin ( Hexa ) , pentaporphyrin ( Penta ) , coproporphyrin ( Copro ) or protoporphyrin ( Proto ) , either in the dark or under UV light . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Effect of beryllium on delta aminolevulinic acid dehydratase and porphobilinogen deaminase in pregnant mice . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| The delta aminolevulinic acid dehydratase and porphobilinogen deaminase activities were significantly elevated in the pregnant untreated group , compared with the nonpregnant mice ( the control group ) . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Ethanol suppresses the activity of porphobilinogen synthase ( synonym : delta aminolevulinic acid dehydratase ) , uroporphyrinogen decarboxylase , coproporphyrinogen oxidase and ferrochelatase , whereas it induces the first and rate limiting enzyme in the pathway , delta aminolevulinic acid synthase and also porphobilinogen deaminase . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| The heavy metal intoxication affected two of the heme synthesis enzymes , ALA dehydratase ( ALAD ) and porphobilinogen deaminase ( PBGD ) . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Heme synthesis and degradation as well as the activities of ALAS , ALAD , PBGD , and FC were found to be increased in the transformed cells . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Lead administration resulted in decreased hemoglobin , increased reticulocytosis , depression of delta aminolevulinic acid dehydratase ( ALAD ) and uroporphyrinogen 1 synthetase ( UPS ) activity in blood and liver . ^^^ Zinc treated rats showed improved hematological profile and activated ALAD and UPS activity , recovery of N demethylation of aminopyrine and O demethylation of p nitroanisole and partial restoration of free thiol levels in blood and liver thereby indicating that zinc could confer protection against lead toxicity . . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Measurements of the activities of aminolevulinate dehydrase , porphobilinogen deaminase , and uroporphyrinogen decarboxylase showed that C inhibits UROD up to nearly 50 % and PBGD activity up to 20 % , but does not affect the activity of ALAD . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| The present results demonstrate that inhibition of globin gene expression by AZT is a direct gene effect rather than a general inhibition of K 562 cell induction as demonstrated by the absence of AZT effects on expression of three other erythroid inducible genes [ erythroid specific aminolevulate synthase ( ALAS E ) , aminolevulinic acid dehydrogenase ( ALAD ) , and erythroid specific porphobilinogen deaminase ( PBGD E ) ] . . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| There are 4 different porphyrin synthesizing enzymes , i . e . delta aminolevulinic acid dehydratase , porphobilinogen deaminase , uroporphyrinogen 3 synthase and uroporphyrinogen decarboxylase , in red blood cells . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| Influence of protein calorie malnutrition and fasting on the activities of delta aminolevulinic acid dehydratase and porphobilinogen deaminase in rats . ^^^ |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08397 and P13716 |
Pubmed |
SVM Score :0.0 |
| NA |
|