| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| One can deduct from experimental and clinical studies that in liver alcohol inhibits the enzymes coproporphyrinogen oxidase , delta aminolevulinic acid dehydratase and uroporphyrinogen decarboxylase and induces delta aminolevulinic acid synthase . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| The action of porphyrins , uroporphyrin 1 and 3 ( URO 1 and URO 3 ) , pentacarboxylic porphyrin 1 ( PENTA 1 ) , coproporphyrin 1 and 3 ( COPRO 1 and COPRO 3 ) , protoporphyrin 9 ( PROTO 9 ) and mesoporphyrin ( MESO ) , on the activity of human erythrocytes delta aminolevulinic acid dehydratase , porphobilinogenase , deaminase and uroporphyrinogen decarboxylase in the dark and under UV light was investigated . ^^^ URO 3 had a similar action as URO 1 on porphobilinogenase and deaminase and PROTO 9 exerted equal effect as URO 1 on delta aminolevulinic acid dehydratase and uroporphyrinogen decarboxylase . ^^^ |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| Low levels of delta aminolevulinic acid dehydratase , porphobilinogen deaminase and uroporphyrinogen decarboxylase activities , and heme concentrations were found in the extract of the parasite walls and scolex , but not in the vesicular fluid . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| There are 4 different porphyrin synthesizing enzymes , i . e . delta aminolevulinic acid dehydratase , porphobilinogen deaminase , uroporphyrinogen 3 synthase and uroporphyrinogen decarboxylase , in red blood cells . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| Aerobic and anaerobic studies have demonstrated that uroporphyrin 1 induced inactivation of delta aminolevulinic acid dehydratase , porphobilinogenase , deaminase and uroporphyrinogen decarboxylase was dependent on oxygen and mediated by reactive oxygen species . ^^^ Upon exposure of the enzymes to the porphyrin under u . v . light , and in an aerobic atmosphere , the percentage of enzyme activities with respect to the corresponding controls were 50 . 2 + / 5 . 1 ( SD , n = 6 ) , 25 . 3 + / 3 . 0 ( SD , n = 6 ) , 25 . 9 + / 2 . 8 ( SD , n = 6 ) and 49 . 7 + / 7 . 5 ( SD , n = 8 ) for delta aminolevulinic acid dehydratase , porphobilinogenase , deaminase and uroporphyrinogen decarboxylase , respectively . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| From experimental and clinical studies the conclusion can be drawn that alcohol inhibits the enzymes delta aminolevulinic acid dehydratase ( synonym : porphobilinogen synthase ) , uroporphyrinogen decarboxylase and coproporphyrinogen oxidase and induces delta aminolevulinic acid synthase in the liver . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| Ethanol suppresses the activity of porphobilinogen synthase ( synonym : delta aminolevulinic acid dehydratase ) , uroporphyrinogen decarboxylase , coproporphyrinogen oxidase and ferrochelatase , whereas it induces the first and rate limiting enzyme in the pathway , delta aminolevulinic acid synthase and also porphobilinogen deaminase . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| We now report effects of iron loading on three enzymes of heme synthesis : 5 aminolevulinate synthase ; the first and rate controlling enzyme of the pathway , 5 aminolevulinate dehydrase ( or porphobilinogen synthase ) , and uroporphyrinogen decarboxylase , the activity of which is decreased in porphyria cutanea tarda , a liver disease in which iron is known to play an important but still poorly understood role . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| Six of the seven mutants were blocked in a different enzyme activity : 5 aminolevulinate synthase , porphobilinogen synthase , uroporphyrinogen 1 synthase , uroporphyrinogen decarboxylase , coproporphyrinogen 3 oxidase and ferrochelatase . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| In contrast to the effects on ALAD , DMSO decreases the activities of porphobilinogen deaminase and uroporphyrinogen decarboxylase . . ^^^ |
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| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| Measurements of the activities of aminolevulinate dehydrase , porphobilinogen deaminase , and uroporphyrinogen decarboxylase showed that C inhibits UROD up to nearly 50 % and PBGD activity up to 20 % , but does not affect the activity of ALAD . ^^^ |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13716 and P06132 |
Pubmed |
SVM Score :0.0 |
| NA |
|