| Interacting proteins: P13688 and Q06124 |
Pubmed |
SVM Score :0.8433955 |
| First , we demonstrate that Bgp 1 also associates with the SHP 2 Tyr phosphatase , but not with an unrelated Tyr phosphatase , PTP PEST . 0.8433955^^^ |
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| Interacting proteins: P13688 and Q06124 |
Pubmed |
SVM Score :0.59067456 |
| CEACAM 1 bound by gonococcal Opa 52 associated with the tyrosine phosphatases SHP 1 and SHP 2 , which implicates the receptor ' s ITIM ( immunoreceptor tyrosine based inhibitory motif ) in this effect . . 0.59067456^^^ |
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| Interacting proteins: P13688 and Q06124 |
Pubmed |
SVM Score :0.0 |
| A group of six mouse monoclonal antibodies ( MoAbs ) with the unusual lambda type light chain were generated by fusion of NS 1 cells with splenic cells derived from BALB / c mice immunized with crude extracts of Bermuda grass pollen ( BGP ) . ^^^ |
|
| Interacting proteins: P13688 and Q06124 |
Pubmed |
SVM Score :0.0 |
| The structural features surrounding the tyrosine residues in the cytoplasmic domain of BGP share similarity with the consensus sequence of the immunoreceptor tyrosine based inhibition motif ( ITIM ) , the docking site for SHIP , SHP 1 , and SHP 2 molecules . ^^^ |
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| Interacting proteins: P13688 and Q06124 |
Pubmed |
SVM Score :0.0 |
| This result is in agreement with our previous studies demonstrating the C terminal region of the cytoplasmic domain influences the levels of CEACAM 1 Tyr phosphorylation and its association with the protein Tyr phosphatases SHP 1 and SHP 2 . ^^^ |
|
| Interacting proteins: P13688 and Q06124 |
Pubmed |
SVM Score :0.0 |
| Functionally , this dephosphorylation correlated with a reduced association between CEACAM 1 and the tyrosine phosphatase SHP 2 . ^^^ |
|
| Interacting proteins: P13688 and Q06124 |
Pubmed |
SVM Score :0.0 |
| This CEACAM 1 promoted cell death pathway does not involve the inhibitory signals or the tyrosine phosphatases SHP 1 and SHP 2 but depends on Bruton ' s tyrosine kinase in DT 40 cells . ^^^ |
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