| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Two epitopes were CEA specific ( D 14 and B7 . 1 ) , one was shared with nonspecific cross reacting antigen ( NCA ) ( B7 . 8 ) , and the fourth ( B 18 ) was common to CEA , NCA , and biliary glycoprotein antigen ( BGP ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The nucleotide sequence of BGP 1 exhibited greater than 80 % identity with CEA and nonspecific crossreacting antigen ( NCA ) in the leader peptide , N terminal domain , and immunoglobulin like domain . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Two antibodies cross reacted strongly with nonspecific cross reacting antigen ( NCA ) while none of the antibodies cross reacted with biliary glycoprotein 1 ( BGP 1 ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| There are several CEA related normal antigens ; nonspecific cross reacting antigen ( NCA ) from normal lung or spleen , NCA 2 from meconium , normal fecal antigen ( NFA ) from normal adult feces , which consists of 3 molecular species ; NFA 1 , NFA 2 and NFCA , and biliary glycoprotein 1 ( BGP 1 ) from bile . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| In addition , the expression of carcinoembryonic antigen and nonspecific crossreacting antigen , which are highly homologous to BGP , was investigated . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| All samples of bile from the patients with biliary cancer showed three bands that corresponded to CEA , nonspecific crossreacting antigen , and biliary glycoprotein 1 , respectively . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Both chimeric Fab fragments exhibited strong immunohistochemical reactivity with various gastrointestinal carcinomas and no reactivity with CEA related antigens , such as NCA ( nonspecific cross reacting antigen ) or BGPI ( biliary glycoprotein 1 ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The other two groups are homologous to the nonspecific cross reacting antigen ( NCA ) and biliary glycoprotein ( BGP ) , both of which are members of the carcinoembryonic antigen ( CEA ) family . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The role of the CD 66 antigens in neutrophil effector function was examined using non cross reacting and cross reacting domain mapped CD 66 monoclonal antibody ( mAb ) , which recognize epitopes on biliary glycoprotein ( BGP ; CD66a ) , CEA gene family member 6 ( CGM 6 ; CD66b ) , nonspecific cross reacting antigen 90 ( NCA 90 ; CD66c ) or CGM 1 ( CD66d ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Cell surface levels of CEA and the CEA family member nonspecific crossreacting antigen ( NCA ) , both overexpressed in colon cancer , were higher in LS 174T than in SW 1222 cells , whereas family member biliary glycoprotein ( BGP ) , downregulated in colon carcinoma was higher in the SW 1222 cells . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Two other CEA family members , biliary glycoprotein ( BGP ) and nonspecific cross reacting antigen ( NCA ) , are similarly expressed , whereas CEA transcripts were found down to the base of the crypts but were less predominant in the upper region . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The result showed the CEA , nonspecific crossreacting antigen 50 / 90 ( NCA ) , biliary glycoprotein ( BGP ) , and carcinoembryonic antigen gene family member 2 ( CGM 2 ) mRNAs were expressed in the colon . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Human carcinoembryonic antigen ( CEA ) , a widely used tumor marker , and CEACAM 6 [ formerly nonspecific cross reacting antigen ( NCA ) ] are up regulated in many types of human cancers , whereas family member CEACAM 1 [ formerly biliary glycoprotein ( BGP ) ] is usually down regulated . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The anti CEA antibody has a high affinity ( 2 . 6 10 10 ( 10 ) M 1 ) for CEA and does not cross react with normal cross reacting antigen , biliary glycoprotein 1 , or tumor extracted , CEA related antigen . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Gonococci and recombinant Escherichia coli strains synthesizing Opa 52 showed specific binding and internalization by transfected HeLa cell lines expressing the CD 66 family members BGP ( CD66a ) , NCA ( CD66c ) , CGM 1 ( CD66d ) and CEA ( CD66e ) , but not that expressing CGM 6 ( CD66b ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Four human carcinoembryonic antigen ( CEA ) family members , CEA ( CD66e ) , non specific cross reacting antigen ( NCA , CD66c ) , biliary glycoprotein ( BGP , CD66a ) and CEA gene family member 2 ( CGM 2 ) , are expressed in normal mucosal epithelia of the colon . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Consistent with this , T 84 cells were shown by reverse transcriptase polymerase chain reaction ( RT PCR ) and immunoblotting to co express CD66a ( BGP ) , CD66c ( NCA ) and CD66e ( CEA ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Four members of the carcinoembryonic antigen family , CEACAM 1 , CEACAM 8 , CEACAM 6 and CEACAM 3 , recognized by CD66a , CD66b , CD66c and CD66d monoclonal antibodies ( mAb ) , respectively , are expressed on human neutrophils . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Ectopic expression of various members of the human carcinoembryonic antigen ( CEA ) family of intercellular adhesion molecules in murine myoblasts either blocks ( CEA , CEACAM 6 ) or allows ( CEACAM 1 ) myogenic differentiation . ^^^ CEA and CEACAM 6 are glycophosphatidyl inositol ( GPI ) anchored , whereas CEACAM 1 is transmembrane ( TM ) anchored . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Four members of the carcinoembryonic antigen ( CEA ) family , CEA , CEACAM 1 ( BGP ) , CEACAM 6 ( NCA 50 / 90 ) , and CEACAM 7 ( CGM 2 ) , are coexpressed in normal colorectal epithelia but are deregulated in colorectal cancers , where they could play a role in tumorigenesis . ^^^ This is well documented for CEACAM 1 and CEA but not for CEACAM 6 or CEACAM 7 . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The carcinoembryonic antigen ( CEA ) gene family members , CEACAM 1 , CEACAM 3 , CEACAM 5 and CEACAM 6 , are bound by the Opa outer membrane proteins of pathogenic Neisseria spp . , whereas CEACAM 8 is not . ^^^ The replacement of residues 27 29 in CEACAM 6 with the CEACAM 1 or CEACAM 5 sequences generated recombinant CEACAM 6 receptors that are bound by CEACAM1 / CEACAM5 specific Opa variants . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| CEACAM 6 reveals homophilic adhesion and heterophilic adhesion to other CEACAM family antigens including CEACAM 8 , CEACAM 1 , and CEA , whereas CEACAM 8 exhibits only heterophilic adhesion to CEACAM 6 . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| For the invasion of epithelial cell lines via CEACAM 1 and CEACAM 6 , a pathogen directed reorganization of the actin cytoskeleton is not required . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| PURPOSE : CEACAM 6 , CEACAM 1 , and human carcinoembryonic antigen ( CEA ) are coexpressed in normal colorectal epithelia , but show deregulated expression in colorectal cancers ( CRC ) . ^^^ The aim of our study was to evaluate the prognostic relevance of CEACAM 6 , CEACAM 1 , and CEA tissue expression in patients with CRC . ^^^ RESULTS : Tissue expression of CEACAM 6 , CEACAM 1 , and CEA was enhanced in 55 % , 58 % , and 94 % of patients , respectively . ^^^ Multivariate Cox analysis including sex , age , tumor site , stage , differentiation grade , treatment , and nodal status as covariates showed that CEACAM 6 overexpression independently predicted poor OS ( HR , 1 . 86 ; P = . 0100 ) and DFS ( HR , 2 . 00 ; P = . 0028 ) , whereas CEACAM 1 or CEA were not significantly related to these outcomes . ^^^ Whether CEACAM 6 or CEA and CEACAM 1 might be useful as predictive markers of chemotherapy benefit remains unclear . . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| CEA , CEACAM 1 , CEACAM 6 and CEACAM 7 , are localized to the apical glycocalyx of normal colonic epithelium and have been suggested to play a role in innate immunity . ^^^ IFN gamma , but not the other agents , modified expression of CEA , CEACAM 1 and CEACAM 6 . ^^^ IFN gamma has two important effects on the expression levels of the CEA family molecules in colon epithelial cells : direct upregulation of CEACAM 1 and promotion of cell differentiation resulting in increased expression of CEA and CEACAM 6 and decreased expression of CEACAM7 . . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Among them , 22 clones produced HmAbs that reacted with CEA but not with 3 other CEA related cell adhesion molecule ( CEACAM ) family members , CEACAM 1 , CEACAM 6 and CEACAM 8 . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Interestingly , human granulocytes express a specific isoform , CEACAM 3 , that participates together with CEACAM 1 and CEACAM 6 in the recognition of CEACAM binding microorganisms . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The results demonstrate that only E . coli expressing a subfamily of Afa / Dr adhesins , named here Afa / Dr 1 , including Dr , F 1845 and AfaE 3 adhesins , bound onto CHO cells expressing CEACAM 1 , CEA or CEACAM 6 . ^^^ Whereas all the Afa / Dr adhesins elicit recruitment of CD 55 around adhering bacteria , only the Afa / Dr 1 subfamily elicits the recruitment of CEACAM 1 , CEA and CEACAM 6 . ^^^ The recruited CEACAM 1 , CEA and CEACAM 6 around adhering bacteria resist totally or in part a detergent extraction , whereas the recruited CEACAM 3 does not . ^^^ Finally , the results show that recognition of CEA and CEACAM 6 , but not CEACAM 1 , is accompanied by tight attachment to bacteria of cell surface microvilli like extensions , which are elongated . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| In this study we demonstrate that CEACAM 1 interacts with CEACAM 5 , but not with CEACAM 6 . ^^^ Sequence alignment reveals a dichotomy among the CEACAM family members : both CEACAM 1 and CEACAM 5 contain the R and Q residues in positions 43 and 44 , respectively , whereas CEACAM 3 and CEACAM 6 contain the S and L residues , respectively . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Carcinoembryonic antigen ( CEA ) , a tumor marker for lung cancers of small cell ( SCLC ) and non small cell ( NSCLC ) types , belongs in a multigene family which includes non specific cross reacting antigen ( NCA ) and biliary glycoprotein 1 ( BGP ) . ^^^ In both lung and colorectal cell lines expression of NCA RNA was relatively high , while BGP RNA was relatively low , and the median concentrations of CEA were greater than in corresponding non malignant tissues . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Using carcinoembryonic antigen ( CEA ) subgroup specific degenerate PCR primers , we have identified three new CEA gene family member L / N exons ( CGM 9 , CGM 10 , and CGM 11 ) and all previously reported L / N exons of the CEA subgroup ( CEA , BGP , NCA , CGM 1 , CGM 2 , CGM 6 , CGM 7 , and CGM 8 ) . ^^^ CEA , BGP , NCA , and CGM 1 form a fairly well supported group within the CEA subgroup . . ^^^ |
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| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The CEA family consists of two structurally and functionally distinct sub groups ; the group including CEA , NCA and CGM 6 which are cell surface bound by phosphatidyl inositol ( PI ) linkages , and the group of BGP splice variants which have trans membrane and cytoplasmic domains . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Immobilized purified CEA ( carcinoembryonic antigen ) , NCA ( non specific crossreacting antigen ) and BGP 1 ( biliary glycoprotein 1 ) bind strains of E . coli ( including EPEC ) and some Salmonella species ( including S . typhi , S . paratyphi A + B and S . java ) while Shigella , Yersinia and Bacteroides strains showed no adhesion . ^^^ The putative role of members of the CEA gene family ( CEA , NCA an BGP ) as ligands for the bacterial colonization of different human epithelial tissues . ^^^ From inhibition studies with aromatic mannose compounds , it was suggested that in contrast to Salmonella strains E . coli strains exhibit a higher hydrophobicity in the binding region adjacent to the CEA , NCA and BGP binding site . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Three Carcinoembryonic Antigen ( CEA ) gene family members : CEA , Non specific cross reactive antigen 50 / 90 ( NCA ) and biliary glycoprotein ( BGP ) were expressed in the colon carcinoma cell lines LS174T and HT 29 . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| In addition , like the cadherins and unlike CEA or NCA or other adhesion molecules of the immunoglobulin supergene family , BGP transfectant aggregation requires physiological temperatures . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Following the recognition of membrane bound receptors , including type 4 collagen , DAF , CEACAM 1 , CEA , and CEACAM 6 , by Afa / Dr adhesins , activation of signal transduction pathways leads to structural and functional injuries at brush border and junctional domains and to proinflammatory responses in polarized intestinal cells . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Its occurrence and localization was studied in normal human gastrointestinal tissues by means of direct immunofluorescence using immunadsorbent purified BGP 1 antibodies with high selectivity for BGP 1 , as compared to CEA and ' non specific cross reacting antigen ' ( NCA ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| It is conceivable that this elevated CEA observed in the cystic fluid might be correlated with CEA like antigens such as NCA , NFA and BGP . . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Therefore , antigen for CEA , NCA and BGP were prepared , and biliary CEA , NCA and BGP levels were measured by the ELISA method . ^^^ In malignant disease , both biliary NCA and biliary BGP increased , though not so remarkable compared with CEA . ^^^ Even in controls , the biliary NCA and BGP levels were not negligible . . ^^^ |
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| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The observations suggest that the gallbladder epithelium may produce CEA and / or some CEA related antigens , except to NCA and BGP 1 , and that the CEA level in bile may be raised in the inflammatory process of cholecystolithiasis . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| They did not react with non specific cross reacting antigen ( NCA ) , biliary glycoprotein 1 ( BGP 1 ) or orosomucoid . 10 20 muCi ( 1 2 micrograms ) of 131I labelled mab was injected intraperitoneally into mice bearing heterografts of the CEA containing human tumor cell lines LS 174T , Detroit 562 or HT 29 or into mice bearing grafts of the non CEA containing human tumor cell line RD . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Members of the carcinoembryonic antigen ( CEA ) family include CEA , non specific cross reacting antigen ( NCA ) , and biliary glycoprotein ( BGP ) , and appear to function as cell adhesion molecules . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Specific primer sets were designed for CEA , non specific cross reacting antigen ( NCA ) , biliary glycoprotein ( BGP ) , carcinoembryonic antigen gene family members 1 , 6 and 7 ( CGM 1 , CGM 6 and CGM 7 ) , and one set for all pregnancy specific glycoprotein ( PSG ) transcripts . ^^^ In ovarian mucinous adenocarcinomas , we always found co expression of CEA and NCA transcripts , and occasionally BGP mRNA . ^^^ CEA , NCA and BGP transcripts were present in endometrial carcinomas of the uterus and cervical carcinomas , whereas uterine leiomyomas were completely negative . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Thereafter , the structures of non specific cross reacting antigen ( NCA ) and biliary glycoprotein 1 ( BGPI ) have also been clarified . ^^^ Each CEA and NCA has hydrophobic domain in the C terminus consisting of 26 amino acids which is eliminated when it binds with membrane and is reconstituted by combining with phosphatidylinositol glycan , whereas BGPI contains transmembrane and cytoplasmic domains . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| When the malignant tissues were compared to the non malignant ones for the intensity of the band , no significant difference was observed . mRNAs of CEA and non specific cross reacting antigen ( NCA ) were not detected in 5 samples which were shown to have the message of the BGP 1 gene . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| B 9 , JA 4 , and AH 3 were suggested to react with CEA related antigens , such as NCA and BGPI , whereas KM 10 and A 10 were suggested to recognize the distinctive part of CEA . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Analysis of these peptides by Edman microsequencing and mass spectrometry established that NCA 160 was identical to biliary glycoprotein 1 , a protein that we previously cloned from a human colon library ( 1 ) . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Mouse cell lines transfected with carcinoembryonic antigen ( CEA ) and with 2 other members of the human CEA gene family , non specific cross reacting antigen ( NCA ) and biliary glycoprotein ( BGP ) , were used to analyze the specificity of several monoclonal antibodies ( MAbs ) . ^^^ The MAb B6 . 2 reacted with cells expressing the NCA gene product but not with those expressing CEA or BGP . ^^^ The MAb B1 . 1 reacted strongly with the transfected CEA and BGP gene products but only weakly with the NCA gene product . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Carcinoembryonic antigen ( CEA ) , biliary glycoprotein ( BGP ) , and non specific cross reacting antigen ( NCA ) are three closely related cell surface glycoproteins induced by gamma interferon ( IFN gamma ) in colonic epithelial cells . ^^^ Northern blot analysis of HT 29 cells treated with IFN gamma and probed with specific probes for BGP , CEA , and NCA showed a 2 fold increase in mRNA level for BGP , and a greater than 10 fold induction for CEA and NCA . ^^^ Similar results were obtained for the SW 403 cell line , but in the case of the LS174T cell line , CEA mRNA levels remained constant before and after IFN gamma treatment , while BGP and NCA mRNA levels increased by 2 5 fold . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| The carcinoembryonic antigen ( CEA ) family comprises a group of glycoproteins including the classical CEA , nonspecific cross reacting antigens ( NCA ) , and biliary glycoprotein ( BGP ) . ^^^ The secretory parts of eccrine sweat glands expressed CEA , NCA 90 , and BGP , whereas apocrine glands remained unreactive for CEA glycoproteins . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| In contrast to previous assumptions , CEA does not represent a single oncofetal antigen but comprises a family of homologous glycoproteins , i . e . the classical CEA 180 , biliary glycoprotein ( BGP ) , and non specific crossreacting antigens ( NCA ) . ^^^ Co expression of CEA 180 , NCA 90 , and BGP was consistent with differentiation towards the secretory part of eccrine glands or the transitional portion of proximal ducts . ^^^ Neoplasms with signs of apocrine secretion showed a preferential immunoreactivity for NCA 90 and BGP . ^^^ |
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| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| CEA , NCA , and BGP have all been shown to function in vitro as intercellular adhesion molecules . ^^^ We show here that the properties of adhesion are radically different , in that BGP mediated adhesion is reversibly Ca2+ and Mg2+ dependent , temperature dependent , and ATP inhibitable , whereas CEA and NCA mediated adhesion is the opposite in all aspects . ^^^ Finally , the myogenic differentiation block demonstrated for the ectopic expression of CEA in myoblasts was also observed for NCA but not for BGP , which is consistent with the changes in expression seen in cancer . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| We have earlier demonstrated that BGP mRNA is expressed in hepatocellular carcinomas ( HCCs ) and the adjacent non cancerous regions , neither of which express CEA and NCA mRNA . ^^^ |
|
| Interacting proteins: P40199 and P13688 |
Pubmed |
SVM Score :0.0 |
| Pretreatment of HepG 2 cells with a polyclonal antiserum directed against all CEA family members , or with a monoclonal antibody , Kat4c ( cd66abde ) , directed against Bgp 1 , CGM 6 , CGM1a , NCA and CEA , significantly reduced virus replication and the capacity of MHV H 2 to infect HepG 2 cells . ^^^ |
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