| Direct binding of N CAM to immobilized neurocan core protein and recombinant neurocan fragments could also be demonstrated , and KD values between 25 and 100 nM were obtained . ^^^ Binding of N CAM to the immobilized neurocan core protein could be inhibited with all recombinant fragments containing chondroitin sulfate or major parts of the mucin like central region of neurocan . ^^^ |