| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| MPB 07 had no apparent effect on the distribution of wild type CFTR , the apical membrane protein CD 59 or the ER membrane Ca ( 2+ ) , Mg ATPase . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Studies of DeltaF ( 508 ) CFTR trafficking using confocal imaging showed that some DeltaF ( 508 ) CFTR colocalised with the apical membrane protein CD 59 ; however a large amount was mislocalised within the cell . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| After 35 days of 3 D culture , ZO 1 , CFTR , ezrin , and CD 59 were apically or subapically located , and well differentiated secretory and ciliated cells were identified . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| It also appeared that the amelioration of CF obtained with a moderate vascular filling ( 300 ml of low molecular weight dextran ) under 10 microgram . kg 1 . min 1 of dobutamine is greatly superior to the amelioration obtained by 10 to 15 microgram . kg 1 . min 1 of dobutamine . . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| CF was found to average 6 . 2 ml 10 min 1 10 100 g 1 at rest and increased to 9 . 2 ml 10 min 1 10 100 g 1 during exercise . ^^^ Additional infusion of adenosine into the distal artery resulted in an increase of CF to 11 . 4 ml 10 min 1 10 100 g 1 and of orthograde flow to 71 ml 10 min 1 10 100 g 1 . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Graphical analysis ( Patlak and Blasberg , 1985 ) of the data is inappropriate due to the high tissue loss rate constant ( kb = 0 . 03 0 . 07 min 1 ) for CF in brain . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| The initial values of AP in BB were lower than those values found in LE ( BB 9 , 10 + / 0 . 57 kPa ; LE 11 , 31 + / 0 . 53 kPa ; p less than 0 . 01 , while CF showed higher values in BB ( 350 + / 8 . 5 min 1 ) ; LE ( 321 + / 10 min 1 ) ; p less than 0 . 05 . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| ECF1 * had an ATPase activity under standard conditions of 93 mumol of ATP hydrolyzed min 1 mg 1 , cf . an activity of 7 . 5 units mg 1 for our standard ECF 1 preparation and 64 units mg 1 for enzyme in which the epsilon subunit had been removed by trypsin treatment . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| There was no indication of enhanced carbohydrate metabolism during Test 2 for the CHO group but mean heart rate was lower during Test 2 than during Test 1 ( 145 + / 14 beat min 1 cf . 152 + / 12 beat min 1 , P less than 0 . 05 ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| After pretreatment with ouabain ( 100 microM ) , Na+o replacement ( Li+ ) increased Ca2+i at a significantly faster rate [ 3 . 6 nM min 1 ( control ) cf . 19 . 8 nM min 1 ( ouabain ) ] . . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Iso ( 40 ng 10 min 1 10 kg 1 ) caused a 30 % increase of CF in both C and D , but no change occurred with NE ( 0 . 4 micrograms 10 min 1 10 kg 1 ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| In both CP and CF perfused lobes , 5 min arachidonic acid ( AA ) infusions ( 0 . 085 + / 0 . 005 to 2 . 80 + / 0 . 16 mg 10 min 1 10 100 g lung 1 ) increased RT , Rv , and Pc ( P less than 0 . 05 at the highest dose ) , while Ra was not significantly altered and Ra / Rv fell ( P less than 0 . 05 at the highest AA dose ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| In all but one CF sputum , TR and Fm were lower than that of the control frog mucus ( median TR : 18 . 7 and 11 . 6 mm min 1 ; median Fm : 12 . 3 and 11 . 3 Hz , respectively ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| The range of apparent Vmax ' s was 6 . 69 9 . 22 nmole mg 1 min 1 for the CF strains and 5 . 59 7 . 87 nmole mg 1 min 1 for the normal strains . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Amrinone , when administered intravenously as a bolus injection ( 1 or 3 mg 10 kg 1 ) plus an infusion ( 0 . 03 or 0 . 1 mg 10 kg 1 10 min 1 ) reversed the depression in cardiac function by increasing CF , CO and LV dp / dtmax and decreasing preload CVP or RAP in all four drug induced failure models . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Total uterine capillary blood flow was significantly greater ( P less than 0 . 01 ) at oestrus than at day 8 of the oestrous cycle [ 69 . 5 + / ( s . e . m . ) 11 . 9 , cf . 15 . 3 + / 1 . 2 ml min 1 , n = 7 ] , reflecting increases of a similar order in both the endometrium and the myometrium . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| The haemodynamic effects of an optimal dose of dobutamine ( DUo ) ( 6 . 7 + / 4 . 2 micrograms kg 1 min 1 ) and the combination of this optimal dose minus 2 . 5 micrograms kg 1 min 1 of dobutamine ( DU ) plus dopamine 2 . 5 micrograms kg 1 min 1 ( DA ) were studied in a first group of 12 consecutive patients with acute myocardial infarction ( AMI ) and cardiac failure ( CF ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Studies of Ca2+ fluxes in cell organelles showed that mitochondria isolated from CF fibroblasts accumulate 2 3 times more Ca2+ than controls [ 79 . 5 + / 8 . 2 versus 33 . 7 + / 4 . 7 nmols 10 mg mitochondrial protein 1 10 10 min 1 ( + / SD ) ] , Ca2+ accumulation in mitochondrial reliably distinguished between CF and control or heterozygote cells ( P less than 0 . 0005 , n = 11 ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| When expressed in terms of gross surface area , basal HCO 3 output was six times greater in the duodenum than in the stomach ( approximately 1 . 5 cf . approximately 0 . 25 mumol 10 cm 2 10 15 min 1 ) . topical application of 16 , 16 dimethyl prostaglandin E 2 ( dmPGE 2 ) to duodenal mucosa caused a concentration dependent increase in HCO 3 output and transmucosal electrical potential difference ( PD ) over the range 0 . 01 1 . 0 microgram 10 ml 1 . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| In the present investigation the effects of hypercapnic acidosis ( increases CO 2 ) and adenosine on coronary sinus flow ( CF ; ml . min 1 . 100 g 1 LV ) were assessed in 13 controls and 7 diabetic lambs ( glucose 1 , 084 + / 193 mg / dl ) given alloxan ( 150 mg / kg ) 2 days prior to study . ^^^ Dose response curves ( 0 . 30 micrograms . min 1 . kg 1 ) indicated a linear relationship between adenosine and CF . ^^^ At infusion rates of 30 ( 4 ) or 3 ( LV ) micrograms . min 1 . kg 1 adenosine increased CF by 30 and 21 ml . min 1 . 100 g 1 LV , respectively in control ( P less than 0 . 001 ) but not in diabetic lambs . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Three hours of low flow ischemia decreased coronary flow ( CF ) from 17 . 4 + / 0 . 13 to 12 . 6 + / 0 . 2 ml 10 min 1 10 g dry tissue 1 . ^^^ During the subsequent 2 h of ischemia , CF of vehicle treated hearts continued to decline to 8 . 0 + / 0 . 76 ml 10 min 1 10 g dry tissue 1 , whereas CF of hyaluronidase treated hearts increased to 15 . 6 + / 1 . 17 ml 10 min 1 10 g dry tissue 1 . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Subsequent intracoronary infusions of L arginine ( 303 mM ; 0 . 25 ml 10 min 1 ) reduced L NAME induced CF changes partly , but did not reverse coronary constriction . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Salbutamol did not elicit bronchodilation in CF patients , but increased heart rate from 77 + / 2 to 103 + / 3 beats min 1 ( P < 0 . 05 ) . 4 . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Adenosine ( 0 . 4 mg . kg 1 . min 1 , intra SMA ) reduced oxygen consumption by 25 . 1 + / 2 . 9 from 73 . 1 + / 10 . 8 micromol . min 1 . 100 g 1 and increased lactate production by 13 . 3 + / 3 . 0 from 12 . 8 + / 4 . 6 micromol . min 1 . 100 g tissue 1 during constant flow ( CF , decreased shear stress ) but not during constant pressure ( CP , increased shear stress ) perfusion . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| In normal , but not CF , epithelia , replacing mucosal Cl with gluconate caused intracellular pH ( pHi ) to increase , and the initial rates ( Delta pH min 1 ) of this increase were modestly augmented ( approximately 26 % ) when normal cells were pretreated with forskolin ( 10 microM ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| Mean arterial pressure was higher in LEG ( P < 0 . 001 ) by min 2 and 10 + / 3 mmHg higher in LEG CF than LEG CE by min 5 ( P < 0 . 001 ) . ^^^ |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13987 and P13569 |
Pubmed |
SVM Score :0.0 |
| NA |
|