| Interacting proteins: O14746 and P12956 |
Pubmed |
SVM Score :0.0 |
| Further , we found that the terminal 3 ' G overhang was significantly extended in ku 70 mutants and in plants deficient in both Ku 70 and the catalytic subunit of telomerase ( TERT ) , implying that Ku is needed for proper maintenance of the telomeric C rich strand . ^^^ Consistent with inefficient C strand maintenance , telomere shortening was accelerated in ku 70 tert double mutants , and the onset of a terminal sterile phenotype was reached two to three times faster than in tert single mutants . ^^^ |
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| Interacting proteins: O14746 and P12956 |
Pubmed |
SVM Score :0.0 |
| Here we describe two PCR based methods to monitor telomere length and examine the fate of dysfunctional telomeres in Arabidopsis lacking the catalytic subunit of telomerase ( TERT ) and the DNA repair proteins Ku 70 and Mre 11 . ^^^ In ku 70 tert mutants , there was a greater incidence of microhomology at the fusion junction than in tert mutants . ^^^ In triple ku 70 tert mre 11 mutants , chromosome fusions were still detected , but microhomology at the junction was no longer favored . ^^^ |
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