| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| A novel src homology 3 domain containing adaptor protein , HIP 55 , that interacts with hematopoietic progenitor kinase 1 . ^^^ |
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| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| B cell adaptor containing src homology 2 domain ( BASH ) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1 . ^^^ |
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| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| We found that actin binding and Src homology 3 ( SH 3 ) domain containing proteins cortactin , hematopoietic specific protein 1 ( HS 1 ) , and hematopoietic progenitor kinase 1 interacting protein of 55 kDa ( HIP 55 , also called SH3P7 and Abp 1 ) were degraded in a caspase dependent manner during apoptosis . ^^^ |
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| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| Here , we show that the proline rich domain of PRAM 1 interacted with the Src homology 3 ( SH 3 ) domain of hematopoietic progenitor kinase 1 ( HPK 1 ) interacting protein of 55 kDa ( HIP 55 , also called SH3P7 and Abp 1 ) known to stimulate the activity of HPK 1 and c Jun N terminal kinase ( JNK ) . ^^^ |
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| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| Subsequent analysis revealed that Src and Syk / ZAP 70 tyrosine kinases and the adaptor proteins LAT , SLP 76 , BLNK , Grb 2 , and Grap are involved in HPK 1 activation . ^^^ |
|
| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| This interaction requires Tyr ( 379 ) of HPK 1 and the Src homology 2 ( SH 2 ) domain of BLNK / SLP 76 . ^^^ |
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| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate the capacity of the Src family kinase Lck and the SLP 76 family adaptor protein Clnk ( cytokine dependent hematopoietic cell linker ) to induce HPK 1 tyrosine phosphorylation and relocation to the plasma membrane , which in lymphocytes results in recruitment of HPK 1 to the contact site of antigen presenting cell ( APC ) T cell conjugates . ^^^ |
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| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92918 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|