| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| Therefore , the backcross procedure dismantles the regulatory gene systems thus permitting Tu directed melanoma formation . 10 erbB * derived from the platyfish , together with the swordtail derived oncogenes src , sis , pdgf r , ras , myc , erbA are expressed or overexpressed in the melanoma , and inositol lipid turnover is considerably elevated . 10 src and inositol lipid turnover have also been found elevated in the healthy tissues ( eg brain ) of the tumourous fish . ^^^ Bs prevents the strain from germ line inherited melanoma but , following carcinogen induced impairment in a somatic cell gives rise to the Tu directed development of clonal melanoma in a particular fish , 10 src activity and inositol lipid turnover are elevated in the tumor but , in contrast to the animals bearing the inherited melanoma , are not elevated in the brain . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| Determination of mercury in fish muscle samples can be made by an anodic stripping voltammetric technique ( ASV ) using a gold disc as the working electrode . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| In the fish Xiphophorus we have detected elevated levels of pp60c src kinase activity in a variety of tumors ( n = 34 ) of neurogenic , epithelial , and mesenchymal origin either of hereditary etiology or induced by carcinogens . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| We were able to demonstrate the presence of c src related sequences in Acrania , Cyclostomata , cartilagenous and bony fish . 6 . ^^^ In lymphocystis tumors of flat fish and in stomatopapilloma of freshwater eels a considerable amount of pp60c src kinase activity was found , which , however , never exceeded the levels found in the normal brain . . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| To this end we have investigated whether the c src gene of a lower vertebrate ( the teleost fish Xiphophorus ) gives rise to a neural specific transcript in an analogous manner . ^^^ We could show that the fish c src gene does encode for a `` fibroblastic ' ' and a `` neuronal ' ' form of transcript and that the neuronal transcript does indeed arise by way of alternative splicing of a mini exon . ^^^ For comparative purposes we have examined whether the fish c yes gene , the member of the src gene family most closely related to c src , also encodes a neural tissue specific transcript . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| To study the evolutionary conservation of the 6 amino acid insert , the expression of pp60c src+ in the brain of animals from different classes was assayed by using pp60c src+ specific antibodies raised against a synthetic peptide corresponding to the insert . pp60c src+ was detected only in the brain of mammals , birds , and reptiles , but not amphibians and fish , whereas pp60c src was present in the brain of all animals tested , including lobster ( invertebrate ) . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| The expression of the c src gene in embryonic and adult tissue of the teleost fish Xiphophorus helleri was analyzed by in situ hybridization . ^^^ The highly conserved fish c src gene was found to be expressed at high levels in midterm embryos , where c src mRNA was localized in developing neurons of the sensory layer of the differentiating retina and in the developing brain . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| To investigate this further , we are studying the expression of the cellular homolog of the Rous sarcoma virus transforming gene ( c src ) during embryogenesis of fish , frog , and chicken by quantitative determination of the activity of the c src encoded protein kinase ( pp60c src ) . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| By quantitative determination of kinase activity in immunoprecipitated pp60c src from fish showing different degrees of Tu expression , we have investigated whether there exists a correlation between the expression of c src and Tu . ^^^ In genotypes with the same genetic background , cells from Tu containing fish express more pp60c src than do cells from fish lacking Tu . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| A new method for isolating tyrosine kinase substrates used to identify fish , an SH 3 and PX domain containing protein , and Src substrate . ^^^ Several potential Src substrates were identified including Fish , which has five SH 3 domains and a recently discovered phox homology ( PX ) domain . ^^^ Fish is tyrosine phosphorylated in Src transformed fibroblasts ( suggesting that it is a target of Src in vivo ) and in normal cells following treatment with several growth factors . ^^^ Treatment of cells with cytochalasin D also resulted in rapid tyrosine phosphorylation of Fish , concomitant with activation of Src . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| We report on the use of fluorescence in situ hybridization ( FISH ) with specific chromosome 8 arm painting to characterize further small supernumerary chromosome 8 derived markers / rings ( SMC / SRC ) identified in three patients . ^^^ The identification of the SMC / SRC was first characterized by FISH specific alpha repeat centromeric probes , second by FISH whole chromosome painting ( WCP ) , and finally by FISH chromosome arm painting ( CAP ) . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| According to Southern and fluorescence in situ hybridisation ( FISH ) analysis the oncogenes c ras , c src and c fos were amplified in Namalwa and Wish cells . reorganisation other than amplification was found for c mos in the three cell cultures investigated . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src transformed cells . ^^^ Fish is a scaffolding protein and Src substrate . ^^^ In Src transformed cells , we observed a dramatic re localization of some Fish molecules to actin rich structures called podosomes ; the PX domain was both necessary and sufficient to effect this translocation . ^^^ In Src transformed cells , ADAM 12 co localized with Fish in podosomes . ^^^ Because members of the ADAMs family have been implicated in growth factor processing , as well as cell adhesion and motility , Fish could be acting as an adaptor molecule that allows Src to impinge on these processes . . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| Inactivation of Rho in Src transformed fibroblasts by dominant negative RhoA or the Rho specific inhibitor C 3 exoenzyme disrupted podosome structure as judged by localization of podosome components F actin , cortactin , and Fish . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| All vertebrate src genes , from fish to human , originated from the same ancestral gene , because they all have 10 introns at conserved positions . ^^^ |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q5TCZ1 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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