| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| In results , 22 proteins were upregulated ( CIDE B [ cell death inducing DFFA like effector B ] , caspase 3 , caspase 8 , Apo 1 / CD95 ( Fas ) , etc . ) and 12 proteins were downregulated ( mitotic checkpoint protein BUB 3 , myc proto oncogene protein [ c myc ] , src substrate cortactin , transforming protein p21A , etc . ) by 5 FU treatment in HeLa cervical carcinoma cells as determined by spot volume ( P < 0 . 05 ) . ^^^ |
|
| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| Pathogen binding induced tyrosine phosphorylation of several host proteins associated with bacterial attachment sites , including FAK and the Src substrate cortactin . ^^^ |
|
| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| The product of the EMS 1 gene , amplified and overexpressed in human carcinomas , is homologous to a 5 src substrate and is located in cell substratum contact sites . ^^^ Our findings , and the previously reported observations in src transformed chicken embryo fibroblasts , suggest that the EMS 1 protein is involved in regulating the interactions between components of adherens type junctions . ^^^ |
|
| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| The EMS 1 gene encodes an 80 / 85 kDa c src substrate and localises with the CCND 1 gene to chromosome 11q13 . ^^^ The degree of tyrosine phosphorylation of EMS 1 protein was also determined and compared with the activity of src family kinases . ^^^ EMS 1 tyrosine phosphorylation was 3 fold higher in BT 474 and T 47D cells , which exhibited relatively high total src activity coupled with expression of both c fyn and c yes , than in MDA MB 453 cells , which expressed only c yes . ^^^ |
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| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| The EMS 1 gene , located at the chromosome 11q13 region , is the human homologue of p80 / p85 cortactin , a chicken pp 60 ( src ) tyrosine kinase substrate . ^^^ |
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| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| The EMS 1 gene encodes cortactin , a cortical actin associated protein that is a substrate for Src kinase and is involved in cytoskeleton organization . ^^^ |
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| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| To date CCND 1 , encoding the cell cycle regulatory gene cyclin D 1 , and EMS 1 , encoding the filamentous actin binding protein and c Src substrate cortactin , are the favored candidates responsible for the emergence of two of the four amplification cores . . ^^^ |
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| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| Fmn 1 is one of the actin regulators with scaffold function , interacting with Profilin , SRC , EMS 1 , FNBP 1 , FNBP 2 , FNBP 3 , FNBP 4 , WBP 4 and alpha catenin . ^^^ |
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| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| Mouse Formin ( Fmn 1 ) is an actin regulator interacting with Profilin , SRC , EMS 1 , FNBP 1 , FNBP 2 , FNBP 3 , FNBP 4 , WBP 4 and alpha catenin . ^^^ |
|
| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| Cortactin , an actin binding protein and a substrate of Src , is encoded by the EMS 1 oncogene . ^^^ |
|
| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14247 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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