| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| Protein binding assays with two Grb 2 mutants , Grb2 / P49L and Grb2 / G203R , which correspond to the loss of function mutants in the Caenorhabditis elegans sem 5 , demonstrated that the dystroglycan Grb 2 association is through beta dystroglycan C terminal proline rich domains and Grb 2 Src homology 3 domains . ^^^ |
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| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| At the level of these internal vesicular structures , we find that tyrosine phosphorylated beta dystroglycan is colocalized with c Src . ^^^ |
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| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| These results suggest that PLC may be involved through inositol trisphosphate generation and calcium mobilization , and that neither DAG nor phosphatidic acid ( PtdOH ) was used as sources of arachidonic acid . 3 The stimulated PGI ( 2 ) synthesis was protein kinase C ( PKC ) independent but strongly inhibited by the mitogen activated protein kinase kinase ( MEK ) inhibitors PD 98059 and U 0126 and by the Src kinase inhibitor PP 1 . 4 Immunoblot experiments showed an increased phosphorylation of the extracellular signal regulated kinases 1 / 2 ( ERK1 / 2 ) upon lymphocyte addition till 4 h coincubation . ^^^ |
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| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| Stimulatory signals include protein phosphorylation , increase in intracellular free calcium , the production of 1 , 4 , 5 triphosphate inositol ( IP ( 3 ) ) and diacylglycerol ( DAG ) mainly through the Src family kinases , phosphoinositide 3 kinase ( PI 3 K ) and phospholipase C ( PLC ) . ^^^ |
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| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14118 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|