| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| Immunocytochemistry , sucrose density gradient sedimentation , co immunoprecipitation analyses and in vitro binding assays have shown that polycystin 1 associates with the focal adhesion proteins talin , vinculin , p130Cas , FAK , alpha actinin , paxillin and pp60c src in subconfluent normal human fetal collecting tubule ( HFCT ) epithelia when cell matrix interactions predominate . ^^^ |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| Steroid receptor coactivator 1 ( SRC 1 ) and PPAR binding protein ( PBP ) interact with PPARgamma and act as coactivators to enhance ligand dependent transcription . ^^^ We report here that PPARgamma , SRC 1 , and PBP are differentially expressed in the brown fat , transitional epithelium of the urinary bladder , colonic mucosa , and mammary epithelium of the adult mouse . ^^^ PPARgamma and PBP are expressed in the transitional epithelium of urinary bladder and in brown adipose tissue , but not SRC 1 . ^^^ In the colonic mucosa , PPARgamma expression occurs throughout the villi , whereas the expression of both SRC 1 and PBP is confined mostly to the crypts . ^^^ The expression of both SRC 1 and PBP is prominent in the breast epithelium of nonpregnant , pregnant , and lactating mice , whereas PPARgamma expression appeared prominent during lactation . ^^^ |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate that both peroxisome proliferator activated receptor binding protein ( PBP ) and steroid receptor coactivator 1 ( SRC 1 ) are required for ligand dependent transcription of transiently transfected and chromosomally integrated reporter genes by the estrogen receptor ( ER ) and retinoic acid receptor ( RAR ) . ^^^ CFP fusions to RAR or its ligand binding domain exhibited rapid ligand dependent FRET to YFP tagged nuclear receptor interaction domains of the coactivators SRC 1 and PBP . ^^^ These findings suggest that ligand dependent transcriptional activities of the RAR and ER require concurrent or sequential recruitment of SRC 1 and PBP containing coactivator complexes . . ^^^ |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| Using PPAR as bait in the yeast two hybrid system , the authors recently cloned mouse steroid receptor coactivator 1 ( SRC 1 ) and PPAR binding protein ( PBP ) , and identified them as PPAR coactivators . ^^^ Both SRC 1 and PBP contain LXXLL signature motifs , considered necessary and sufficient for the binding of coactivators to nuclear receptors . ^^^ |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| We now report that PIMT strongly interacts with transcriptional coactivators , CBP , p 300 , and PBP but not with SRC 1 and PGC 1alpha under in vitro and in vivo conditions . ^^^ |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| PRIC complex includes known coactivators or coactivator binding proteins ( CBP , SRC 1 , PBP , PRIP , PIMT , TRAP 100 , SUR 2 , and PGC 1 ) , other proteins that have not previously been described in association with transcription complexes ( CHD 5 , TOG , and MORF ) , and a few novel polypeptides designated PRIC 300 , 285 , 215 , 177 , and 145 . ^^^ |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98161 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|