| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :1.3811565 |
| CONCLUSIONS : Like the other related Tec kinases , Rlk is associated with lipid RAFTs and can be phosphorylated and activated by Src family kinases , supporting a role for Rlk in signaling downstream of Src kinases in T cell activation . . 1.3811565^^^ |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| We further show that Rlk is phosphorylated and changes localization in response to T cell receptor ( TCR ) activation and , like the other Btk family kinases , can be phosphorylated and activated by Src family kinases . ^^^ |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| A protein fragment from the Tec family member Rlk ( also known as Txk ) containing a single proline rich ligand adjacent to a Src homology 3 ( SH 3 ) domain has been investigated by nuclear magnetic resonance ( NMR ) spectroscopy . ^^^ |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| Members of the Tec kinase family ( Bmx , Btk , Itk , Rlk and Tec ) are primarily expressed in the hematopoietic system and form , after the Src kinase family , the second largest class of non receptor protein tyrosine kinases . ^^^ |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| TXK , like BTK , is a member of the Tec sub family of Src type ( non receptor ) tyrosine kinases . ^^^ Like similar Tec sub family members , and unlike the other Src kinases , TXK lacks both the N terminal myristylation signal and the C terminal regulatory tyrosine . ^^^ TXK shares 60 % amino acid homology with EMT and 57 % with BTK over the SH 3 , SH 2 ( Src homology ) and catalytic domains but unlike BTK , EMT and tec , it lacks Gap 1 homology and steroid hormone receptor homology in the N terminal region . ^^^ |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| To date the src gene family consists of at least 9 closely related protein tyrosine kinases belonging to the non receptor type of kinases : c src , c yes , c fgr , fyn , lyn , lck , hck , tkl and bkl . ^^^ |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42681 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|