| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.98173159 |
| In exploring the molecular mechanism involved in HNF 1 dependent gene activation in the in vivo chromatin context , we found that HNF 1 can physically interact with the histone acetyltransferases ( HATs ) CREB binding protein ( CBP ) , p300 / CBP associated factor ( P / CAF ) , Src 1 , and RAC 3 . 0.98173159^^^ |
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| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| We show that the AFs that bind the gAF 1 , gAF 2 , and gAF 3 elements ( hepatocyte nuclear factor [ HNF ] 4 / chicken ovalbumin upstream promoter transcription factor 1 and HNF3beta ) all interact with steroid receptor coactivator 1 ( SRC 1 ) . ^^^ |
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| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| Our laboratory has previously demonstrated that retinoic acid nuclear receptor , thyroid transcription factor 1 ( TTF 1 ) , and nuclear receptor coactivators such as cAMP response element binding protein ( CREB ) binding protein ( CBP ) / p300 and steroid receptor coactivator 1 ( SRC 1 ) form an enhanceosome on the 5 ' enhancer region of the human surfactant protein B gene . ^^^ |
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| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| Role of CBP / p300 and SRC 1 in transcriptional regulation of the pulmonary surfactant protein A ( SP A ) gene by thyroid transcription factor 1 ( TTF 1 ) . ^^^ |
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| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| In a second transgenic mouse line , an enhancer region , which binds to thyroid transcription factor 1 , retinoic acid receptor , signal transducers and activators of transcription 3 , and nuclear receptor coactivators ( SRC 1 , ACTR , TIF 2 , and CBP / p300 ) , was deleted from the hSP B 1 . 5 kb lacZ gene . ^^^ |
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| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| The overexpression of SRC 1 or GRIP 1 enhances expression from a HNF 1 gene promoter reporter in HepG 2 hepatoma cells , and this requires an intact HNF 4 binding site in the HNF 1 gene promoter . ^^^ |
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| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| These results indicate that SRC transcriptional regulation is much more complex than previously realized and implicates HNF 1 in both the tissue specific regulation of the SRC gene in normal tissues and the overexpression of c Src in certain human cancers . . ^^^ Mutation of the HNF 1 site resulted in a dramatic reduction in SRC promoter activity . ^^^ |
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| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20823 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|