| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.57049226 |
| These data suggest that ( 1 ) SH 2 and SH 3 ligand sites on Sin cooperatively activate the signaling potential of c Src , ( 2 ) Sin acts as both an activator and a substrate for c Src , and ( 3 ) phosphorylated Sin may serve as a signaling effector molecule for Src by binding to multiple cellular proteins . . 0.57049226^^^ |
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| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| Molecular cloning of a cDNA encoding a phosphoprotein , Efs , which contains a Src homology 3 domain and associates with Fyn . ^^^ |
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| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| Dot far western blot analysis of relative binding affinities of the Src homology 3 domains of Efs and its related proteins . ^^^ |
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| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| Spontaneous rhythmic contractions ( SRC , < 4 mHz ) and EFS induced contractions of RA are endothelium independent and weaker than contractions induced by exogenously applied vasoconstrictors . ^^^ |
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| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| To this end , we used full length and truncated versions of the multiadapter molecules Cas and Sin to activate c Src , and we examined the intracellular pathways that mediate Src signaling under these conditions . ^^^ Src signaling induced by the adapters Sin and Cas is mediated by Rap 1 GTPase . ^^^ In addition , we show that Sin and Cas induced Src signaling , as assayed by transcriptional activation , is exclusively mediated through a pathway that involves the adapter Crk and the GTP binding protein Rap 1 . ^^^ |
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| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| In this study , we examined the role of the T lymphocyte expressed adapter protein and Src kinase substrate , Sin , on thymocyte function using transgenic mice expressing an activated , truncated allele of Sin ( SinDeltaC ) . ^^^ Because the adapter properties of Sin are mediated by tyrosine based motifs and given that Sin is a substrate for Src tyrosine kinases , we examined the involvement of these kinases in the inhibitory effects of SinDeltaC . ^^^ |
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| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| In contrast to other adapters that become phosphorylated upon TCR stimulation , Sin was constitutively phosphorylated in resting cells by the Src kinase Fyn and bound to signaling intermediates , including PLC gamma . ^^^ |
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| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43281 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|