| Interacting proteins: O43184 and P12931 |
Pubmed |
SVM Score :1.1139619 |
| Moreover , endogenous ADAM 12 associates with and activates endogenous Src in differentiating C2C12 cells . 1.1139619^^^ |
|
| Interacting proteins: O43184 and P12931 |
Pubmed |
SVM Score :0.0 |
| Based on analysis of deletions and mutations of the cytoplasmic tail of ADAM 12 L , the retention signal is comprised of both the cytoplasmic and transmembrane domains , but not the Src homology 3 domain ( SH 3 ) binding sites . ^^^ |
|
| Interacting proteins: O43184 and P12931 |
Pubmed |
SVM Score :0.0 |
| In Src transformed cells , ADAM 12 co localized with Fish in podosomes . ^^^ |
|
| Interacting proteins: O43184 and P12931 |
Pubmed |
SVM Score :0.0 |
| To determine how ADAM 12 is activated , we screened proteins that bind to the cytoplasmic domain of ADAM 12 using a yeast two hybrid system and identified a protein called PACSIN 3 that contains a Src homology 3 domain . ^^^ |
|
| Interacting proteins: O43184 and P12931 |
Pubmed |
SVM Score :0.0 |
| Meltrin alpha cytoplasmic domain interacts with SH 3 domains of Src and Grb 2 and is phosphorylated by 5 Src . ^^^ Src and Grb 2 in bovine brain extracts also bound to meltrin alpha cytoplasmic domain on affinity resin . ^^^ Furthermore , immunoprecipitation with a monoclonal antibody to meltrin alpha resulted in coprecipitation of Src and Grb 2 with meltrin alpha in cell extracts , suggesting that Src and Grb 2 are associated in vivo with meltrin alpha cytoplasmic domain . ^^^ The C terminal Tyr 901 of meltrin alpha was phosphorylated both in vitro and in cultured cells by 5 Src . ^^^ |
|
| Interacting proteins: O43184 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
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