| Interacting proteins: Q13253 and P12644 |
Pubmed |
SVM Score :0.0 |
| The secreted polypeptide noggin ( encoded by the Nog gene ) binds and inactivates members of the transforming growth factor beta superfamily of signalling proteins ( TGFbeta FMs ) , such as BMP 4 ( ref . 1 ) . ^^^ |
|
| Interacting proteins: Q13253 and P12644 |
Pubmed |
SVM Score :0.0 |
| In mandibular explants , ectopic BMP 4 rapidly induces expression of both Chd and Nog , consistent with results obtained in vivo with mutant embryos . ^^^ |
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| Interacting proteins: Q13253 and P12644 |
Pubmed |
SVM Score :0.0 |
| Evaluation of BMP 4 and its specific inhibitor NOG as candidates in human neural tube defects ( NTDs ) . ^^^ Studies on animal models have shown that BMP 4 and NOG are involved in the patterning of the neural tube . ^^^ Our SSCA screen revealed four missense mutations in BMP 4 and one in NOG . ^^^ |
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| Interacting proteins: Q13253 and P12644 |
Pubmed |
SVM Score :0.0 |
| In addition , Shh upregulates several mesenchymal cell markers , including its target gene Patched ( Ptc ) , intercellular signaling genes Bone Morphogenetic Protein 4 ( Bmp 4 ) and Noggin ( Nog ) , and smooth muscle actin and myosin . ^^^ |
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| Interacting proteins: Q13253 and P12644 |
Pubmed |
SVM Score :0.0 |
| The abnormalities in foregut and lung morphogenesis of Nog null mutant can be rescued by reducing the gene dose of Bmp 4 by 50 % . ^^^ |
|
| Interacting proteins: Q13253 and P12644 |
Pubmed |
SVM Score :0.0 |
| NA |
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