Ectodin inhibited the activity of BMP 2 , BMP 4 , BMP 6 , and BMP 7 for mouse preosteoblastic MC3T3 E 1 cells , and bound to these BMPs with high affinity . ^^^ BMP 2 and BMP 7 stimulated ectodin expression in tooth explants , showing that it is part of a feedback mechanism controlling the activity of BMPs . ^^^ |