| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| In contrast BMP 2 and transforming growth factor beta 2 are inactive . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| Temporally and spatially distinct patterns of BMP 2a , Vgr 1 , TGF beta 1 , and TGF beta 2 expression are also seen in different populations of mesenchymal cells in the developing skeletal system ( cartilage and bone ) . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| Normal odontoblast and in vitro induced odontoblast like cells expressed transcripts encoding for TGF beta 1 and 3 , BMP 2 and 4 , bone sialoprotein and osteonectin whereas either ubiquitous expression or no expression could be detected for TGF beta 2 , IGF 1 or fibronectin mRNAs . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| Surface plasmon resonance measurements show that fetuin binds directly to TGF beta 1 and TGF beta 2 and with greater affinity to the TGF beta related bone morphogenetic proteins ( BMP 2 , BMP 4 , and BMP 6 ) . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| The novel assay has been used to characterize affinities and specificities of TGF beta 3 , TGF beta 2 , corresponding mutants and hybrid proteins , as well as a related protein , BMP 2 . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| In this study , we investigated the effects and interactions of local factors ( BMP 2 and TGF beta 2 ) on HBMS cell proliferation and differentiation in short term and long term cultures . ^^^ The data show that TGF beta 2 acts by increasing HBMS cell proliferation and type 1 collagen synthesis whereas BMP 2 acts by promoting HBMS cell differentiation . ^^^ These observations suggest that TGF beta 2 and BMP 2 may act in a sequential manner at different stages to promote human bone marrow stromal cell differentiation towards the osteoblast phenotype . . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| Although mRNAs of TGF betas ( TGF beta 1 , TGF beta 2 and TGF beta 3 ) were detected , those of inhibin / activin ( alpha , betaA and betaB subunits ) and BMPs ( BMP 2 , BMP 4 and BMP 7 ) could not be detected in the cells , suggesting that neither activins nor BMPs are produced in F 5 5 . fl cells . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| The WT 1 mutant tumors overexpressed genes encoding myogenic and other transcription factors ( MOX 2 , LBX 1 , SIM 2 ) , signaling molecules ( TGFB 2 , FST , BMP2A ) , extracellular Wnt inhibitors ( WIF 1 , SFRP 4 ) , and known beta catenin / TCF targets ( FST , CSPG 2 , CMYC ) . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| The earliest changes ( days 1 3 ) involved accelerated expression profiles for IGF 1R and VEGF and up regulation of TGF beta 2 , TbetaRI , BMP 2 , BMP 7 , and Cbfa 1 . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| MFB F 11 cells were highly induced by TGF beta 1 , TGF beta 2 and TGF beta 3 , but did not show induction with related family members activin , nodal , BMP 2 and BMP 6 or with trophic factors bFGF and BDNF . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| Compared with the relevant contralateral controls , energy to failure was increased 3 . 5 fold in association with TGF beta 2 alone ( p < 0 . 05 ) , 4 . 5 fold in association with TGF beta 2 combined with BMP 2 ( p < 0 . 01 ) , and 2 . 5 fold in association with autogenous bone grafting . ^^^ CONCLUSIONS : In this animal model , the combined use of TGF beta 2 and BMP 2 led to more secure mechanical fixation of the implant than did the use of either growth factor alone and demonstrated results that were similar to those associated with the use of autogenous bone graft . . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| In this study , we investigated the in vitro effect of avocado and soya unsaponifiables ( ASU ) on the expression of TGF beta 1 , TGF beta 2 , and bone morphogenetic protein 2 ( BMP 2 ) by human periodontal ligament ( HPL ) and human alveolar bone ( HAB ) cells in the presence of IL 1beta . ^^^ The steady state levels of TGF beta 1 , TGF beta 2 , and BMP 2 mRNAs were determined by Northern blot or reverse transcription polymerase chain reaction ( RT PCR ) . ^^^ The ASU stimulation of TGF beta 1 , TGF beta 2 , and BMP 2 expression may explain their promoting effects in the treatment of periodontal disorders , at least partly . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| Transforming growth factor beta 2 enhances the osteoinductive activity of a bovine bone derived fraction containing bone morphogenetic protein 2 and 3 . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| The repeated sampling bone chamber was used in the goat to investigate the properties of bone allografts enriched with transforming growth factor beta , recombinant human bone morphogenetic protein 2 , and basic fibroblastic growth factor under unfavorable vascular and nonloaded conditions . ^^^ The concentrations of the growth factors used was 0 , 1 , or 10 micrograms of transforming growth factor beta 2 , 0 , 1 , or 5 micrograms of bone morphogenetic protein 2 , and 0 , 40 , 200 ng of basic fibroblastic growth factor . ^^^ In the 5 micrograms of bone morphogenetic protein 2 specimens , larger amounts of soft tissue and woven bone were present , whereas in the specimens that received 10 micrograms of transforming growth factor beta 2 , there was a decrease in the amount of tissue and bone ingrowth . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| In this study , the dose dependent response of bovine chondrocytes to recombinant human insulin like growth factor 1 , recombinant human transforming growth factor beta 2 , and recombinant human bone morphogenetic protein 2 was studied in an alginate culture system under different culture conditions . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| In the current study , the potential of other members of the transforming growth factor beta superfamily ( transforming growth factor beta 2 , transforming growth factor beta 3 , bone morphogenetic protein 2 and bone morphogenetic protein 13 ) , and of insulinlike growth factor 1 , epidermal growth factor , transforming growth factor alpha , and Tenascin C , to induce chondrogenesis within the authors ' adult miniature pig articular cartilage defect model , was evaluated . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| BMP 2 had a cooperative effect with low doses of brain derived neurotrophic factor or neurotrophin 3 ( but not with other neurotrophic factors such as glial cell line derived neurotrophic factor , neurturin or transforming growth factor beta 2 ) on the number of calbindin positive striatal neurones . ^^^ |
|
| Interacting proteins: P61812 and P12643 |
Pubmed |
SVM Score :0.0 |
| Fibrosis stimulating growth factors ( transforming growth factor beta 1 , transforming growth factor beta 2 , bone morphogenetic protein 2 , and endothelial growth factor ) were expressed at significantly higher levels in PV CD 34 ( + ) cells . ^^^ |
|