| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| The crystal structure of the complete signaling complex formed between bone morphogenetic protein 2 ( BMP 2 ) and the extracellular domains ( ECDs ) of its type 1 receptor [ bone morphogenetic protein receptor type Ia ( BMPR Ia ) ECD ] and its type 2 receptor [ activin receptor type 2 ( ActRII ) ECD ] shows two fundamental structural constraints for receptor assembly . ^^^ |
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| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| The posterior boundary of actR IIa is consistent with the posterior boundary of nkx 2 . 5 expression , supporting a model whereby ActR IIa is involved in restricting the heart forming region to an anterior subset of lateral cells exposed to BMP 2 . ^^^ |
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| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| The binding epitopes of BMP 2 for BMPR IA ( type 1 ) and BMPR 2 or ActR 2 ( type 2 ) were characterized using BMP 2 mutant proteins for analysis of interactions with receptor ectodomains . ^^^ |
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| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| Semiquantitative reverse transcription polymerase chain reaction ( RT PCR ) demonstrated the presence of various BMPs ( BMP 2 , 3 , 4 , 6 , 7 , and 8A and 8B ) , BMP type 1 and 2 receptors ( ALK 2 , ALK 3 , ALK 4 , BMPR 2 , and ActR IIA and IIB ) , BMP antagonists ( DAN , gremlin , chordin , cerberus , noggin , and tsg ) , and Smads 1 8 . mRNA expression of these genes did not change during differentiation , except for BMP 3 , BMP 8a , and noggin . ^^^ |
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| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| BMP type 1 receptors , including activin receptor like kinase 2 ( ALK 2 ) ( also referred to as ActRIA ) and ALK 3 ( BMPRIA ) , both type 2 receptors , ActRII and BMPRII , as well as the ligands BMP 2 , 4 , and 7 and inhibin / activin subunits were expressed in PC 12 cells . ^^^ |
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| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| AC cells were found to : ( 1 ) express mRNA for multiple BMPs ( BMP 2 , 3 , 4 , 6 , 8a ) , growth / differentiation factors ( GDF 1 , 3 , 5 , 9 ) , Lefty A and B , and the inhibin alpha , beta ( A ) and beta ( B ) subunits ( 2 ) secrete inhibin A and inhibin B and ( 3 ) express mRNA encoding the inhibin co receptor , betaglycan , along with activin and BMP type 1 ( ALK 2 7 ) and type 2 ( ActRII , ActRIIB , BMPRII ) receptors , and binding proteins ( follistatin , BAMBI , gremlin ) . ^^^ |
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| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| Here , we show the existence of mRNA for BMP 2 and for the BMP receptors BMPR1A , BMPR1B , BMPRII , ACVR1A , ACVR 2 , and ACVR2B in differentiated mouse podocytes and the protein expression of BMPR1A in human glomerular podocytes . ^^^ |
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| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P27037 |
Pubmed |
SVM Score :0.0 |
| NA |
|