| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| The expression of Col2a1 , a downstream response gene of Sox 9 , was also significantly increased upon BMP 2 addition . ^^^ |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| This capacity was positively associated with the expression of fibroblast growth factor receptor 3 , bone morphogenetic protein 2 , and alpha 1 ( 2 ) collagen ( COL2A1 ) , and its loss was marked by the up regulation of activin receptor like kinase 1 messenger RNA . ^^^ |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| Cells placed in a 3 dimensional matrix of alginate beads and cultured in a serum free media with bone morphogenetic protein 2 and 9 induced expression of type 2 collagen ( Col2A1 ) mRNA and increased expression of aggrecan and cartilage oligomeric matrix protein suggesting chondrogenic differentiation of the cells . ^^^ |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| A region encompassing the chondrocyte specific enhancer , localized in intron 1 of type 2 collagen alpha 1 chain ( Col2a1 ) gene , is sufficient to confer BMP 2 dependent transcriptional induction of type 2 collagen gene expression . ^^^ |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| For gene analysis , conventional and quantitative polymerase chain reactions were used for COL1A2 , COL2A1 , aggrecan , BMP 2 , biglycan , decorin , osteonectin , fibromodulin , fibronectin , matrix metalloproteinase 13 ( MMP 13 ) , and tissue inhibitor of MMP 1 . ^^^ |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| Wnt8c further enhanced canonical bone morphogenetic proteins ( BMP 2 ) induced expression of Runx 2 and col10a1 while Wnt8c and Wnt9a inhibited TGF beta induced expression of Sox 9 and col2a1 . ^^^ |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P12643 and P02458 |
Pubmed |
SVM Score :0.0 |
| NA |
|