Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Receptors for IgG ( Fc gamma RI , Fc gamma RII and Fc gamma 3 ) are present on trophoblast but allotypy is limited to the NA 1 NA2 antigen system associated with Fc gamma RIII on neutrophils . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Within the three Fc gamma R families ( Fc gamma RI , Fc gamma RII and Fc gamma RIII ) , the presence of distinct genes and alternative splicing variants leads to a variety of receptor isoforms that are most strikingly different in the transmembrane and intracellular regions . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Mononuclear phagocytes in the synovium of patients with arthritis , in contrast to blood monocytes , were found to express a third receptor for the constant region of Ig ( Fc gamma RIII ) , in addition to Fc gamma RI and Fc gamma RII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We found 1 ) increased FMLP receptor and decreased C5a receptor expression , 2 ) a normal expression of intracellular FMLP receptors after incubation with PMA , 3 ) increased loss and decreased re expression of FMLP receptors after incubation with this peptide , 4 ) normal expression of adhesion glycoproteins CR 3 ( CD11b / CD18 ) and LFA 1 ( CD11a / CD18 ) , 5 ) further signs of in vivo preactivation : high expression of Fc gamma RI ( CD 64 ) and Fc gamma RII ( CD 32 ) , decreased expression of Fc gamma RIII ( CD 16 ) , increased expression of CD 14 , and low expression of HLA DR . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In this work , we demonstrated the presence of Fc gamma RI , Fc gamma RII and Fc gamma RIII on the oolemma of unfertilized human oocytes by means of monoclonal antibodies directed against these receptors , detected both by immunobead rosetting and indirect immunofluorescence . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Unlike the human Fc gamma RII and Fc gamma RIII families , which exhibit considerable diversity at both the nucleic acid and protein levels , the human Fc gamma RI family has only a single recognized product expressed as a 70 kD cell surface receptor with high affinity for monomeric IgG ( hFc gamma RIa 1 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
It has not been determined which of the three subclasses of human Fc gamma R on myeloid cells ( Fc gamma RI , Fc gamma RII , or Fc gamma RIII ) function to enhance Ag presentation . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Human monocytes and macrophages bear three classes of cell surface receptors for the Fc portion of IgG ( Fc gamma RI , Fc gamma RII , and Fc gamma RIII ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Different classes of receptors for the Fc moiety of IgG ( Fc gamma R ) have been defined on human monocytes and macrophages : Fc gamma RI , Fc gamma RII , and Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The three forms of Fc gamma receptor carried by monocytes ( Fc gamma RI , 2 ) and natural killer ( NK ) cells ( Fc gamma RIII ) are all capable of mediating cell lysis . ^^^ The lysis mediated by BsAb reactive with Fc gamma RI or 2 was unaffected by the presence of human Fc gamma at 2 . 5 mg / ml ( a concentration comparable with that yielded by IgG in plasma ) whereas the BsAb recognizing Fc gamma RIII and all the Fc containing derivatives were completely inhibited . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Finally , we have used these receptor specific probes to demonstrate that all three families of Fc gamma R ( Fc gamma RI , Fc gamma RII and Fc gamma RIII ) expressed on human monocytes and human macrophages are phagocytic receptors . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI and Fc gamma RIII protein was not detected in these cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
IFN alpha selectively augments phagocytosis of IgG2a , with a highly significant induction of Fc gamma RI mRNA expression , while parallel Fc gamma RIII alpha measurements show a relatively small increase . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Consistently there was increased expression by macrophages of CD 14 , ICAM 1 ( CD 54 ) , Fc gamma RI ( CD 64 ) , Fc gamma RII ( CDw 32 ) , Fc gamma RIII ( CD 16 ) , transferrin receptors ( CD 71 ) and tissue factor . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In an attempt to address this question , we investigated the ability of human monocytes to carry out ADCC at the single cell level , with emphasis on the role of the three FcR for IgG ( Fc gamma RI , Fc gamma RII , and Fc gamma RIII ) in mediating cytotoxicity . ^^^ Significant increases in the number of plaque forming cells were observed after positive selection by flow microfluorimetry for those monocytes expressing high levels of Fc gamma RI and Rc gamma RII , but not Fc gamma RIII . ^^^ Bispecific antibodies composed of Fab fragments of anti oxE antibody covalently coupled to Fab fragments of anti Fc gamma R antibodies were used to independently evaluate the ability of Fc gamma RI , Fc gamma RII , and Fc gamma RIII to mediate single cell cytotoxicity . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
FMF analysis was performed demonstrating that freshly isolated eosinophils express Fc gamma RII ( CD 32 ) , small amounts of Fc gamma RIII ( CD 16 ) , but not Fc gamma RI ( CD 64 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Sodium dodecyl sulfate polyacrylamide gel electrophoresis analysis of the immunopurified Fc gamma R molecules revealed the following apparent molecular mass for each Fc gamma R class : Fc gamma RI , 70 kDa ; Fc gamma RII , 44 kDa ; and Fc gamma RIII , 57 65 kDa . ^^^ RNA blot analysis demonstrated a 1 . 7 kb transcript for Fc gamma RI , 2 . 5 and 1 . 6 kb transcripts for Fc gamma RII , and a 2 . 2 kb mRNA for Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Neutrophils from healthy donors express the low affinity receptors for IgG Fc gamma RII ( CD 32 ) and Fc gamma RIII ( CD 16 ) , but not the high affinity receptor Fc gamma RI ( CD 64 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The three types of IgG FcR ( Fc gamma RI , Fc gamma RII , Fc gamma RIII ) on human leukocytes play an important role in elimination of antibody coated infectious agents . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The analysis revealed that Fc gamma RI was expressed on Hofbauer cells , that Fc gamma RII was expressed on Hofbauer cells and endothelial cells of fetal vessels , while Fc gamma RIII was expressed on trophoblasts , especially syncytiotrophoblasts . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Erythrocytes sensitized with these or control mAb were compared in U 937 rosette and monocyte chemiluminescence assays to determine Fc gamma receptor 1 ( Fc gamma RI ) mediated functional activity , and in lymphocyte rosette and lymphocyte antibody dependent cell mediated cytotoxicity ( ADCC ) assays to study Fc gamma RIII mediated binding and lysis . ^^^ These data suggest that glycosylation of IgG is required for CH 2 domain interactions with both Fc gamma RI and Fc gamma RIII , but not for CH 3 domain interactions with Fc gamma RIII . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The expression of Fc gamma RII and Fc gamma RIII is decreased , the expression of Fc gamma RI , CD 66 and CD 67 is increased . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma Rs ( Fc gamma RI , Fc gamma RII , and Fc gamma RIII ) are highly expressed on human mononuclear phagocytes and function in the clearance of immune complexes and opsonized pathogens . ^^^ We have examined the role of Fc gamma R in mediating antibody dependent clearance of HIV 1 by human monocytes and monocyte derived macrophages by using bispecific antibodies ( BsAbs ) to independently target the virus to Fc gamma RI , Fc gamma RII , or Fc gamma RIII . ^^^ Interaction of HIV 1JRFL with Fc gamma RI or Fc gamma RII on human monocytes and Fc gamma RI , Fc gamma RII , or Fc gamma RIII on monocyte derived macrophages resulted in markedly reduced levels of virus production in these cultures . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Antibodies to Fc gamma R indicated that engagement of Fc gamma RII and Fc gamma RIII , but not Fc gamma RI , receptors was related to the O 2 response of neutrophils to immune complexes . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Unstimulated EoL 3 cells expressed Fc gamma RII as determined by monoclonal antibody ( mAb ) 4 3 , whereas there was little or no Fc gamma RI and Fc gamma RIII expression as determined by mAbs 32 . 2 and 3G8 , respectively . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three types of FcR react with IgG : Fc gamma RI is a high affinity receptor binding IgG monomers whereas Fc gamma RII and Fc gamma RIII are low affinity receptors binding IgG immune complexes ; the three types of Fc gamma R are members of the Ig superfamily . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Hybridoma cell lines ( HC ) bearing antibody directed to Fc gamma RI ( HC 32 ) , Fc gamma RII ( HC IV . 3 ) or Fc gamma RIII ( HC 3G8 ) were used as targets , as were chicken erythrocytes ( CE ) sensitized with heteroantibodies composed of anti Fc gamma R mAbs ( 32 , IV . 3 , 3G8 ) linked to anti CE antibody . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Monocytes can express three classes of FcR for IgG : Fc gamma RI , Fc gamma RII , and Fc gamma RIII ( CD 64 , CD 32 , and CD 16 , respectively ) of which the Fc gamma RIII is expressed after prolonged culture . ^^^ We show that IL 4 down regulates Fc gamma RI , Fc gamma RII , and Fc gamma RIII expression of cultured monocytes and inhibits IFN gamma enhanced Fc gamma RI expression . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In this study we use an erythroleukemia cell line , K 562 , which has Fc gamma RII , but does not have Fc gamma RI or Fc gamma RIII , to determine if Fc gamma RII can mediate infection by dengue virus antibody complexes . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Circulating monocytes express Fc gamma RI and Fc gamma RII , but not Fc gamma RIII , and no inducing agent for Fc gamma RIII has previously been identified . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
This protein , which appears to be identical to a 60 , 000 MW IgG binding protein ( 60 IBF ) previously isolated from normal human PBL culture supernatants , also appears to be distinct from the three well defined leucocyte Fc gamma receptors : Fc gamma RI , Fc gamma RII and Fc gamma RIII . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Evidence from several experimental approaches allows us to conclude that the primary amino acid sequence of the lower hinge region ( residues 234 237 ) of human IgG molecules determines recognition by human Fc gamma RI , Fc gamma RII and Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Monocyte cell surface markers that increase with maturation ( i . e . , Fc gamma RIII ) or with activation ( i . e . , Fc gamma RI ) were unaffected by incubation with M CSF . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The receptor appears to be distinct from other opsonic receptors since downmodulation of CR 1 , CR 3 , Fc gamma RI , Fc gamma RII , and Fc gamma RIII with mAbs did not affect binding of LBP coated particles , and leukocytes from CD 18 deficient patients bound LBP coated particles normally . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
However , neither cell type lysed HC bearing antibody to Fc gamma RI or Fc gamma RIII , or CE in the presence of anti CE 10 anti Fc gamma RI HA . ^^^ Treatment of neutrophils with IFN gamma for 18 h induced the expression of Fc gamma RI on these cells and their ability to lyse anti Fc gamma RI or Fc gamma RII bearing HC and CE through Fc gamma RI , Fc gamma RII , and Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Moreover , the expression of Fc gamma RII was not affected by proteolysis as evidenced by immunofluorescence studies and Scatchard analysis , and neither were Fc gamma RI or Fc gamma RIII induced . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI was present on approximately 80 % of the cells , whereas Fc gamma RII and Fc gamma RIII were present on 30 % and 20 % of the cells , respectively . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Human monocytes and macrophages express three different classes of cell surface receptors for the Fc portion of IgG , Fc gamma RI ( CD 64 ) , Gc gamma RII ( CD 32 ) , and Fc gamma RIII ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three distinct Fc receptors for IgG , Fc gamma RI , Fc gamma RII and Fc gamma RIII are known to be associated with human myeloid cells . ^^^ Hybridoma cells ( HC ) expressing anti Fc gamma RI , Fc gamma RII or Fc gamma RIII upon their surface were used as model self directed tumor targets . ^^^ Monocytes were able to utilize Fc gamma RI , Fc gamma RII and Fc gamma RIII in killing both CE and HC targets , and incubation with rIFN gamma augmented their ability to kill CE , particularly through Fc gamma RI . ^^^ Fc gamma RII and Fc gamma RIII mediated killing of CE by untreated neutrophils . rIFN gamma induced PMNs to express Fc gamma RI and to mediate killing of CE through this receptor . ^^^ Moreover , HC targets were not lyzed by untreated neutrophils , but rIFN gamma activated neutrophils killed HC bearing surface anti Fc gamma RI and anti Fc gamma RII , but not anti Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Basophils did not react with a murine monomeric IgG2a , which binds specifically through its Fc to the high affinity Fc gamma RI ( CD 64 ) , or with MAbs specific for the low affinity Fc gamma RIII ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We have used the anti Fc gamma R bearing hybridoma cell lines ( HC ) as self directed targets for ADCC to analyse the triggering ability of each of the three defined Fc gamma R ; Fc gamma RI , Fc gamma RII , and Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI and Fc gamma RII expression was unaltered by 24 h of treatment with DEX alone , but Fc gamma RIII expression was sometimes increased by about 20 % on PMN cultured with DEX . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The expression of Fc gamma RI , Fc gamma RII and Fc gamma RIII on granulocytes in the blood of patients with systemic lupus erythematosus was investigated . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The N terminal end of the CH 2 domain of chimeric human IgG 1 anti HLA DR is necessary for C1q , Fc gamma RI and Fc gamma RIII binding . ^^^ Changing the glycine at 237 to alanine of IgG 1 also abolished Fc gamma RI binding and reduced human complement lysis and Fc gamma RIII mediated function . ^^^ Exchanging the whole region 233 236 with the sequence found in human IgG 2 , abolished Fc gamma RI binding and human complement lysis and reduced Fc gamma RIII mediated function of IgG 1 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI and Fc gamma RIII expression remained low throughout the culture period . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI and Fc gamma RIII on polymorphonuclear leucocytes in cord blood . ^^^ Fc gamma RI and Fc gamma RIII expression on polymorphonuclear leucocytes in cord blood from seven normal infants was investigated by flow cytometry . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We show that LFA3TIP inhibition requires expression of both the LFA 3 and CH 2 domains of the fusion protein that bind CD 2 and Fc gamma RI or Fc gamma RIII , respectively . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The expression of the three classes of Fc gamma R was lower on BMM than on PBM , in percentage ( Fc gamma RI 56 + / 23 versus 79 + / 17 % , p = 0 . 02 ) , density of expression ( Fc gamma RIII MFI 71 + / 20 versus 153 + / 73 , p = 0 . 002 ) , or both ( Fc gamma RII 74 + / 22 % versus 94 + / 12 % , p = 0 . 02 , and MFI 115 + / 53 versus 202 + / 59 , p = 0 . 003 ) . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Treatment of PMN with the regulatory neuropeptide substance P also enhanced adhesion to HAIgG coated fibres and caused increased surface expression of Fc gamma RI , Fc gamma RII and Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The emerging picture of Fc gamma receptor structural diversity several different receptor families ( Fc gamma RI , Fc gamma RII and Fc gamma RIII ) each with different isoforms , the potential for different glycoforms and cell anchoring mechanisms , and allelic variations within the isoforms provides the basis for structure / function relationships which have clear implications for autoimmune diseases with abnormal Fc receptor function . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We found a significantly enhanced expression of Fc gamma RI , CD 14 and CD 54 and a decrease in the level of Fc gamma RIII during G CSF treatment . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Thus , these results indicate that G CSF activated neutrophils exert their cytotoxic effect against neuroblastoma cells through Fc gamma RI and not Fc gamma RIII , and that the saturation of the high affinity Fc gamma RI by monomeric IgG can be overcome by the use of bispecific antibodies binding epitopes outside the IgG Fc gamma RI binding site . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The effect of exposure of PMN to extracellular oxidants on the PMN oxidative burst on the subcellular location of CD 64 ( Fc gamma RI ) , CD32w ( Fc gamma RII ) , CD 16 ( Fc gamma RIII ) , CD 35 ( complement receptor 1 ) , and CD11b / CD18 ( complement receptor 5 ) was studied . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Signal transduction by T and B cell Ag receptors and certain receptors for Ig Fc regions ( Fc gamma RI , hFc gamma RIIA , Fc gamma RIII , Fc alpha R , and Fc epsilon RI ) involves a conserved sequence motif , termed an immunoreceptor tyrosine based activation motif ( ITAM ) and found in multiple receptor chains . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
High affinity Fc gamma RI plays a major role in the effector function of circulating monocytes and splenic mononuclear phagocytes , whereas Fc gamma RIII , expressed strongly on the latter effectors , participates in target ingestion . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Roles have been proposed for Fc receptors , complement , and complement receptors in the pathogenesis of these disorders , although the contribution of each to autoimmune injury is unclear . gamma chain deficient mice lacking Fc gamma RI and Fc gamma RIII are resistant to the development of experimental immune hemolytic anemia induced by polyclonal rabbit anti mouse red blood cell IgG antibodies . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Similarities with human Fc gamma RI , Fc gamma RII , Fc gamma RIII , Fc epsilon RI , or bovine Fc gamma RII were less than 28 % . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
As previously reported , IL 10 stimulated Fc gamma RI expression on monocytes but did not induce the expression of Fc gamma RII , Fc gamma RIII , CR 1 , and CR 3 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
A small decrease in expression was found for Fc gamma RI and Fc gamma RIII ( p < 0 . 05 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In functional assays with Fc receptor ( Fc gamma R ) positive effector cells , the highly galactosylated LD form of BRAD 3 was more active than the HD form in monocyte ( Fc gamma RI ) and K cell ( Fc gamma RIII ) mediated lysis of erythrocytes in ADCC assays , although these preparations showed no difference in Fc gamma RI mediated rosette formation with U 937 cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In contrast , IGF 1 did not alter the PMNL surface expression of Fc gamma RI ( CD 64 ) , Fc gamma RII ( CDw 32 ) , or Fc gamma RIII ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Consistent with these data we have proposed that Fc gamma RI , Fc gamma RII and Fc gamma RIII recognise overlapping non identical interaction sites in the lower hinge region of the CH 2 domain of the IgG molecule . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We have established that isoforms of each of the 3 classes of the Fc gamma receptors , Fc gamma RI , Fc gamma RII and Fc gamma RIII , are able to transmit a phagocytic signal in the absence of the other receptor class . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Isoforms of each of the three classes of the noncatalytic Fc gamma receptors , Fc gamma RI , Fc gamma RII , and Fc gamma RIII , are able to transmit a phagocytic signal in transfected COS 1 cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Greater than 75 % of inflammatory SFs tested ( a total of 22 fluids to date ) increased cell surface expression and dramatically increased mRNA levels of monocyte activation markers Fc gamma RI , Fc gamma RIII , and HLA DRA . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The CD11b ( CR 3 alpha ) , CD 14 , Fc gamma RI , and Fc gamma RIII markers were bimodally distributed . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The expression of Fc gamma RI , Fc gamma RII , and Fc gamma RIII ( the IgG receptors CD 64 , CD 32 , CD 16 ) as well as CR 3 ( the C3bi receptor , CD11b ) on monocytes in the blood of patients with systemic lupus erythematosus ( SLE ) was investigated . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We studied the effect of dibutyryl cyclic adenosine 3 ' , 5 ' monophosphate ( dbcAMP ) and several cytokines on the expression of IgG Fc receptor subclasses ( Fc gamma RI , Fc gamma RII , and Fc gamma RIII ) and low affinity IgE Fc receptors ( Fc epsilon RII / CD23 ) on peripheral eosinophils and on eosinophils differentiated in vitro from cord blood mononuclear cells by interleukin 5 ( IL 5 ) . ^^^ These eosinophils expressed Fc gamma RII , and few , if any , Fc gamma RI and Fc gamma RIII as determined by flow cytometry with specific monoclonal antibodies . dbcAMP enhanced the Fc gamma RII expression , but did not induce the Fc gamma RI and Fc gamma RIII expression . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI ( CD 64 ) , Fc gamma RII ( CDw 32 ) and Fc gamma RIII ( CD 16 ) are expressed by cells of the maternal decidual layer associated with the amniochorion . ^^^ Fc gamma RI ( CD 64 ) , Fc gamma RII ( CDw 32 ) and Fc gamma RIII ( CD 16 ) are expressed by cells of the maternal decidual layer associated with the amniochorion . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Treatment of MDMs with TNF alpha ( 400 pg / ml ) or IL 1 beta ( 400 pg / ml ) for 80 min decreased cell surface Fc gamma RIII expression , as measured by flow cytometry ( FACS ) , while the levels of surface Fc gamma RI and Fc gamma RII remained unchanged . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Anti Fc gamma RI or anti Fc gamma RII mAb , but not anti Fc gamma RIII mAb , efficiently stimulated the intracellular killing of bacteria by monocytes . ^^^ Cross linking Fc gamma RI or Fc gamma RII , but not Fc gamma RIII , on monocytes with mouse anti Fc gamma R mAb followed by bridging with F ( ab ' ) 2 fragments of goat anti mouse IgG enhanced this process . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Murine monoclonal anti human antibodies directed against neutrophil adhesion protein receptors CD 35 , CD 18 , CD11b , CD11c and the Fc receptors CD 64 ( Fc gamma RI ) , CD 32 ( FC gamma RII ) and CD 16 ( Fc gamma RIII ) were evaluated regarding their ability to bind to the canine homologues . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The gamma subunit of immunoglobulin Fc receptors is an essential component of the high affinity receptor for IgG ( Fc gamma RIII ) and is associated with the high affinity receptor for IgG ( Fc gamma RI ) and the T cell receptor CD 3 complex . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
After incubation for 2 hours , surface expression of Fc gamma RI ( CD 64 ) , CD 66 , and CD 67 was up regulated ; Fc gamma RII ( CDw 32 ) , Fc gamma RIII ( CD 16 ) , and LAM 1 were down regulated . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Lipopolysaccharide induced suppression of erythrocyte binding and phagocytosis via Fc gamma RI , Fc gamma RII , Fc gamma RIII , and CR 3 receptors in murine macrophages . ^^^ Phagocytosis via all Fc receptors ( Fc gamma RI , Fc gamma RII , and Fc gamma RIII ) was suppressed by LPS . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Similarly , anti CDw 32 mAb ( 2E1 , anti Fc gamma RII ) , anti CD 64 mAb ( 32 . 2 anti Fc gamma RI ) , and anti CD 16 mAb ( Leu 11a , anti Fc gamma RIII ) mAb each failed to stimulate GM 1056 cells , and more importantly did not block IgG 2 induced stimulation . ^^^ These results indicate that monomeric IgG 2 specifically enhances B cell responses via an Fc gamma R receptor distinct from Fc gamma RI , Fc gamma RII , and Fc gamma RIII , and that IL 6 may play a role in augmenting this response . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The expression of Fc gamma RII or Fc gamma RIII was a little lower than those of adult peripheral blood PMNs , but the expression of Fc gamma RI ( 43 . 1 + / 26 . 8 % ) was significantly higher than that of adult peripheral blood PMNs ( 3 . 2 + / 1 . 8 % ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Consistent with a major role for Fc gamma RI in triggering the responses of U 937 cells , erythrocytes sensitized with chimaeric human IgG 3 did not induce superoxide generation by neutrophils which express Fc gamma RII and Fc gamma RIII , or eosinophils which express Fc gamma RII , but neither of which expresses Fc gamma RI . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three classes of human Fc gamma receptors exist , Fc gamma RI , Fc gamma RII and Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
RESULTS : PTs were positively stained with 3G8 and Leu 1 1b against Fc gamma RIII , partially stained with MAb against MHC class 1 , but not with 32 . 2 ( Fc gamma RI ) , IV 3 ( Fc gamma RII ) , or MAbs against CD 4 , CD 19 , or CD 56 , indicating that only low affinity receptor , Fc gamma RIII , is expressed on PTs . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We have extended these observations to an investigation of the effects of IFN gamma and glucocorticoids on steady state mRNA levels of the three Fc gamma R genes expressed on murine macrophages : Fc gamma RI , Fc gamma RII , and Fc gamma RIII alpha . ^^^ Dexamethasone ( DEX ) significantly increased the expression of IFN gamma induced Fc gamma RI mRNA but had no effect on the expression of Fc gamma RII or Fc gamma RIII alpha transcripts in untreated or IFN gamma treated cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The present study utilized monoclonal antibodies ( MAb ) to determine whether the Agg CRP potentiation of oxidative metabolism could be linked to activation through Fc gamma RI , Fc gamma RII , or Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Human hematopoietic cells express three biochemically distinct classes of Fc gamma receptors : Fc gamma RI ( CD 64 ) , Fc gamma RII ( CD 32 ) and Fc gamma RIII ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
As an approach to understanding their role in neonatal life , we have compared the constitutive expression of the three Fc receptors Fc gamma RI ( CD 64 ) , Fc gamma RII ( CD 32 ) and Fc gamma RIII ( CD 16 ) by neonatal and adult blood monocytes and granulocytes using quantitative immunofluorescence by flow cytometry . ^^^ Neonatal granulocytes expressed significantly higher levels of both Fc gamma RI and Fc gamma RII but significantly lower levels of Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
All DMEC do not express CD 16 ( Fc gamma RIII ) or CD 64 ( Fc gamma RI ) molecules . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Bispecific immunoconjugates were constructed by chemical fusion of a GRP analog or a GRP antagonist with monoclonal antibodies directed to the cytotoxic trigger molecules Fc gamma RI and Fc gamma RIII on various immune effector cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI and Fc gamma RII were purified from cultured cells , and Fc gamma RIII was produced as a recombinant molecule . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three classes of Fc receptors for IgG , Fc gamma RI ( CD 64 ) , Fc gamma RII ( CD 32 ) , and Fc gamma RIII ( CD 16 ) , are expressed on blood leukocytes . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In antibody dependent cell mediated cytotoxicity ( ADCC ) assays , lysis of EA IgG 2 anti A was mediated via Fc gamma RIIa , whereas lysis of EA IgG 1 and EA IgG 3 anti D was mediated via Fc gamma RI or Fc gamma RIII ; EA IgG 2 anti D was inactive in all functional assays . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RIII cross linking stimulated PBMC to release 5 times more IL 8 than did either Fc gamma RI or Fc gamma RII clustering ( p = 0 . 001 ) and stimulated 77 % more IL 8 release from PBMC than that from purified monocytes ( p = 0 . 001 ) . ^^^ Thus , monocyte IL 8 is stimulated directly through Fc gamma RI cross linking and indirectly through an Fc gamma RIII stimulated soluble lymphocyte factor . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
CD 4 , FC gamma RI , and FC gamma RIII expression on CBM were comparable to PBM . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In addition , the IgG receptors Fc gamma RI ( CD 64 ) , Fc gamma RII ( CD 32 ) , and Fc gamma RIII ( CD 16 ) , as well as the complement receptor CR 3 ( CD11b / CD18 ) , were assessed . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We also investigated the types of receptors for the immunoglobulins ( Fc epsilon RI , Fc epsilon RII , Fc gamma RI , Fc gamma RII , and Fc gamma RIII ) on epidermal LCs in the patients . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
TNF alpha decreased the effect of G CSF on apoptosis , expression of Fc gamma RIII and Fc gamma RI , and bactericidal function . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In normal subjects , three parameter immunophenotyping of whole blood revealed that 61 . 3 + / 6 . 0 % of monocytes showed `` bright ' ' expression of the lipopolysaccharide receptor ( LPSR : CD 14 ) and Fc gamma receptor 1 ( RI : CD 64 ) without expression of Fc gamma RIII ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI ( CD 64 ) levels were significantly up regulated with the 7 . 5 micrograms / kg dose by 96 h whereas Fc gamma RIII ( CD 16 ) expression was found to be reduced during G CSF treatment . ^^^ Fc gamma RI ( CD 64 ) levels were significantly up regulated with the 7 . 5 micrograms / kg dose by 96 h whereas Fc gamma RIII ( CD 16 ) expression was found to be reduced during G CSF treatment . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We tested two Fc gamma receptor 1 ( Fc gamma RI ) ; six Fc gamma RII ; and six Fc gamma RIII specific monoclonal antibodies ( mAb ) for their capacity to inhibit monocyte and polymorphonuclear granulocyte ( PMN ) immune phagocytosis which is mediated by Fc gamma R . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
A human CD4+ T cell line expresses functional CD 64 ( Fc gamma RI ) , CD 32 ( Fc gamma RII ) , and CD 16 ( Fc gamma RIII ) receptors but these do not enhance the infectivity of HIV 1 IgG complexes . ^^^ However , we report here that C 8166 cells , a human CD4+ T lymphoblastoid cell line , widely used in research into the human immunodeficiency virus type 1 ( HIV 1 ) , expressed CD 64 ( Fc gamma RI ) , CD 32 ( Fc gamma RII ) , and CD 16 ( Fc gamma RIII ) on the plasma membrane as shown by immunostaining with specific monoclonal antibody fragments . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Flow cytometry demonstrated Fc receptors Fc gamma RI , Fc gamma RII , and Fc gamma RIII on PBMC , but only Fc gamma RII on the B cell line . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Blood leukocytes differentially express two additional IgG FcR , Fc gamma RI ( CD 64 ) and Fc gamma RIII ( CD 16 ) , which may also participate in leukocyte functions such as phagocytosis , Ab dependent cellular cytotoxicity ( ADCC ) , release of oxygen intermediates , and enhancement of Ag presentation . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Membrane expression of Fc gamma RI , Fc gamma RII , Fc gamma RIII , CR 1 , CR 3 and Fc gamma R and CR mediated phagocytosis were not modified by the cytokine . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
METHODS : We measured the expression of the receptors for the constant ( Fc ) region of IgG ( Fc gamma RI , Fc gamma RII , and Fc gamma RIII ) and that for the complement fragments C3b and C3bi ( CR 1 and CR 3 ) in neutrophils and monocytes from 39 children with atopic dermatitis , 17 disease control patients with acute infections , and 17 healthy control subjects . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
There are three classes of Fc gamma receptor proteins , Fc gamma RI ( CD 64 ) , Fc gamma RII ( CDw 32 ) , and Fc gamma RIII ( CD 16 ) , which are encoded by at least eight genes . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI , Fc gamma RII and Fc gamma RIII on Hofbauer cells in the stroma probably clear immune complexes , together with Fc gamma RII on endothelial cells . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The structure for the three human Fc gamma receptors classes Fc gamma RI ( CD 64 ) , Fc gamma RII ( CD 32 ) and Fc gamma RIII ( CD 16 ) has been well characterized . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Inflammatory macrophages from these knockout mice were unable to mediate phagocytosis or Ab dependent cell mediated cytotoxicity ( ADCC ) through Fc gamma RI , Fc gamma RII , or Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
PLD activity was also stimulated by immune complex coated latex beads or cross linking of Abs specific for Fc gamma RI , Fc gamma RII , or Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
These receptors are classified in three different groups ( Fc gamma RI , Fc gamma RII and Fc gamma RIII ) depending upon their molecular weight , affinity and specificity for their ligands . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma R expression in the acute phase of KD is thus characterized by markedly increased expression of Fc gamma RI on neutrophils , followed by a subsequent decrease , and decreased expression of Fc gamma RIII on neutrophils and increased expression of Fc gamma RIII on monocytes followed by a reverse kinetics during the clinical course . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three strains of Fc gamma R deficient mice were examined : gamma chain deficient mice that lack Fc gamma RI and Fc gamma RIII , Fc gamma RII deficient mice , and mice deficient in both gamma chain and Fc gamma RII that lack all Fc gamma R . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In contrast to the constitutive expression of the low affinity receptors for IgG ( Fc gamma RII [ CD 32 ] and Fc gamma RIII [ CD 16 ] ) , the high affinity receptor Fc gamma RI ( CD 64 ) is barely detectable on unactivated PMNs . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
High resolution mapping of the binding site on human IgG 1 for Fc gamma RI , Fc gamma RII , Fc gamma RIII , and FcRn and design of IgG 1 variants with improved binding to the Fc gamma R . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We have demonstrated that members of each of the three classes of human Fc gamma receptors , Fc gamma RI , Fc gamma RII , and Fc gamma RIII , mediate phagocytosis , but that important differences exist in their requirements for phagocytic signaling . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The N terminal end of the C ( H ) 2 domain of chimeric human IgG 1 anti HLA DR is necessary for C1q , Fc gamma RI and Fc gamma RIII binding . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
This reduction in platelets was , however , not observed in mice deficient for the FcR gamma chain , lacking Fc gamma RI , Fc gamma RIII , and Fc gamma RIII ( / ) mice . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three main classes of leukocyte Fc gamma Rs can be distinguished : Fc gamma RI , Fc gamma RII and Fc gamma RIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen induced arthritis . ^^^ In a previous study we found that if a chronic T cell mediated antigen induced arthritis ( AIA ) was elicited in knee joints of FcR gamma chain deficient mice that lack functional Fc gamma RI and Fc gamma RIII , joint inflammation was comparable but severe cartilage destruction was absent . ^^^ We now examined the individual role of the stimulatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and functional cartilage damage in knee joints with AIA using Fc gamma RI , Fc gamma RII , and Fc gamma RIII deficient mice . ^^^ Humoral ( total IgG , IgG 1 , IgG2a , and IgG2b levels ) immunity against mBSA was comparable in Fc gamma RI / and Fc gamma RIII / but higher in Fc gamma RII / if compared to controls . ^^^ Joint swelling as measured by ( 99m ) Tc uptake at days 1 , 3 , and 7 was similar in Fc gamma RI / and Fc gamma RIII / mice and significantly higher in Fc gamma RII / . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
METHODS : Gingival biopsies were stained for mast cell tryptase and chymase , neutrophil elastase , CD 68 , human transforming growth factor beta ( 1 ) , HLA DR , Fc gamma RI , Fc gamma RII and Fc gamma RIII and calprotectin . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Using antibodies to inhibit Fc gamma RI , Fc gamma RII or Fc gamma RIII , the only receptor utilised in the monocyte CL and ADCC assays for interactions with EA IgG 1 was found to be Fc gamma RI . ^^^ Other IgG 1 and IgG 3 Mabs appeared to promote haemolysis through Fc gamma RI and Fc gamma RIII while IgG 2 was inhibited by Mabs to both Fc gamma RII and Fc gamma RIII , suggesting a variety of Fc gamma R are utilised for anti D of low haemolytic activity . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
To further examine the role of the Ig and especially of the Fc portion of the IgG in tolerogenesis , we transduced LPS blasts from FcR gamma 2 ( / ) , Fc gamma RI ( / ) , Fc gamma RIII ( / ) , FcR ( / ) or naive mice with retroviral vectors expressing IgG 1 102 , Delta IgG 1 102 ( mutated construct on position 297 of the Fc portion ) or IgG 12 26 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In vitro , chemically linked bispecific antibodies directed against the Fc gamma receptors Fc gamma RIII ( CD 16 ) and Fc gamma RI ( CD 64 ) , and the Fc alpha receptor Fc alpha RI ( CD 89 ) , were significantly more effective than conventional IgG antibodies . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In contrast , mice lacking the common Fc receptor gamma chain ( FcR gamma / ) , resulting in reduced expression of Fc gamma RI and lack of Fc gamma RIII , and mice lacking Fc gamma RIIB ( Fc gamma RIIB / ) , responded equally well to immunization with IgG 3 complexed Ag as wild type controls . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
ADCC was inhibited by antagonistic antibodies to Fas L and to CD 16 ( Fc gamma RIII ) but not to CD 64 ( Fc gamma RI ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The high affinity Fc gamma receptor ( CD 64 ) induces phagocytosis in the absence of its cytoplasmic domain : the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI . ^^^ In contrast , coexpression in COS 1 cells of Fc gamma RI with the gamma subunit of Fc gamma RIIIA conferred phagocytic function to both Fc gamma RI and the MT Fc gamma RI lacking the cytoplasmic domain . ^^^ Thus , Fc gamma RI does not require its cytoplasmic domain to mediate a phagocytic signal and interacts with the gamma subunit of Fc gamma RIIIA to induce phagocytosis . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI and Fc gamma RIIIA do not possess cytoplasmic tyrosines , but transmit a phagocytic signal through interaction with an associated gamma subunit which contains two YXXL sequences in a conserved motif required for phagocytosis . ^^^ The protein tyrosine kinase Syk , which is associated with the gamma chain in monocytes / macrophages , dramatically enhances phagocytosis mediated by Fc gamma RI and Fc gamma RIIIA and also induces non phagocytic Fc gamma RI or Fc gamma RIIIA expressing cells to acquire phagocytic capability . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
OBJECTIVE : To study the role of the activating Fc gamma receptor types 1 and 3 ( Fc gamma RI and Fc gamma RIII , respectively ) and the inhibiting Fc gamma receptor 2 ( Fc gamma RII ) in inflammation and in various aspects of cartilage destruction during arthritis that is solely induced by immune complexes . ^^^ METHODS : Immune complex mediated arthritis ( ICA ) was passively induced by lysozyme antilysozyme complexes in Fc gamma RI , Fc gamma RIII , and Fc gamma RII knockout mice and their wild type controls . ^^^ Initiation of erosive cartilage destruction , as reflected by MMP mediated VDIPEN expression , was reduced in Fc gamma RIII ( / ) and Fc gamma RI ( / ) mice , directing the two different critical steps of cellular influx and subsequent activation . ^^^ In Fc gamma RI ( / ) and Fc gamma RIII ( / ) mice , VDIPEN expression was 90 99 % lower , whereas in Fc gamma RII ( / ) mice , VDIPEN expression was increased 4 fold . ^^^ CONCLUSION : During ICA , Fc gamma RIII is the dominant activating receptor mediating joint inflammation , whereas both Fc gamma RI and Fc gamma RIII are involved in cartilage destruction . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
METHODS : Together with changes in disease activity and several cell markers , the expression of Fc gamma RI , Fc gamma RIIa , and Fc gamma RIII was determined on granulocytes and monocytes / macrophages from the peripheral blood of 6 patients with active RA before and after treatment with recombinant human IL 10 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Current models of Fc gamma R signal transduction in monocytes describe a molecular cascade that begins upon clustering of Fc gamma R with the phosphorylation of critical tyrosine residues in the cytoplasmic domains of Fc gamma RIIa or the gamma chain subunit of Fc gamma RI and Fc gamma RIIIa . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
By contrast , culture with IL 3 caused an up regulation of eosinophil FcRII expression but did not induce expression of FcRI or FcRIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
This protective effect of IFN gamma on PMN function was associated with the prolonged surface expression of the complement receptor three ( CR 3 ) alpha chain ( CD11b ) , CR 3 beta chain ( CD 18 ) , FcRII ( CD 32 ) , and FcRIII ( CD 16 ) , and the appearance of surface FcRI ( CD 64 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Monoclonal antibodies and flow cytometry were used to assess the expression of Fc gamma receptors ( FcRI , FcRII , FcRIII ) and complement receptors ( CR 1 , CR 3 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
FcR gamma chain has previously been shown to interact with the TCR CD 3 complex , the IgE Fc receptor 1 ( Fc epsilon RI ) , and the class 1 and IIIA IgG receptors ( Fc gamma RI and Fc gamma RIIIa ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc gamma RI and Fc gamma RIIIA do not possess cytoplasmic tyrosines but transmit a phagocytic signal through interaction with an associated gamma subunit that contains two YXXL sequences in a conserved motif required for phagocytosis . ^^^ The data indicate that coexpression of the protein tyrosine kinase Syk , which is associated with the gamma chain in monocytes / macrophages , is important for phagocytosis mediated by Fc gamma RI and Fc gamma RIIIA . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Two classes of FcR that bind the Fc portion of IgG , Fc gamma RI , and Fc gamma RIIIa associate with a subunit shared among several FcR , the gamma chain , which is involved in receptor expression and signal transduction . ^^^ Our findings demonstrate that Fc gamma RI requires gamma chain association to attain high affinity binding for monomeric IgG , and suggest that the intermediate binding affinity of the Fc gamma RIIIa isoform results from its association with gamma chain . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Rabbit IgG coated sheep E ( Rb EAs ) were recognized by FcRI , FcRII and possibly also by FcRIII of human macrophages . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three classes of Fc gamma receptors ( FcR ) have been identified on blood leukocytes : FcRI , FcRII , and FcRIII . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc receptors for IgG ( FcR ) on epidermal cells in suspension were studied using soluble immune complexes and monoclonal antibodies ( MoAbs ) against FcR 1 , FcR 2 and FcR 3 using an indirect immunofluorescence technique . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Expression of receptors for the Fc moiety of immunoglobulin G ( FcRI , FcRII , FcRIII ) , CD 14 , and HLA DR was assayed by indirect immunofluorescence with monoclonal antibodies . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The presence of Fc receptors for IgG , FcRI ( CD 64 ) , FcRII ( CD 32 ) and FcRIII ( CD 16 ) in human peripheral nerves was studied by indirect immunofluorescence staining of cryostat sections with monoclonal antibodies ( mabs ) . ^^^ The mabs 32 . 2 against FcRI , IV . 3 and C1KM5 against FcRII , B1D6 against a 40 kD FcR with low affinity for IgG , and Leu 11b and 3G8 against FcRIII stained a few scattered cells in the endoneurium , apparently monocytes / macrophages . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
MoAbs against FcR 1 ( 32 . 2 ) , FcR 2 ( IV . 3 and C1KM5 ) and FcR 3 ( 3G8 and Leu11b ) stained interstitial macrophages only . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Synovial lining cells express numerous macrophage associated antigens , including CD11b ( CR 3 ) , CD 13 , CD 14 , CD 16 ( FcRIII ) , CD 18 , CD 32 ( FcRII ) , CD 45 ( leucocyte common antigen ) , CD 54 ( ICAM 1 ) , CD 64 ( FcRI ) , CD 68 , and CD 71 ( transferrin receptor ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
This conclusion was confirmed by immunoprecipitation experiments , whereas no specific immunoprecipitate was noted with the anti FcRI or anti FcRIII mAb , the anti FcRII mAb immunoprecipitated a protein of Mr 40 kDa . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc receptors for IgG , FcRI ( CD 64 ) , FcRII ( CD 32 ) , and FcRIII ( CD 16 ) in human placenta were studied by indirect immunohistochemistry using avidin biotin peroxidase complexes for the staining of cryostat sections . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Preligation of the FcRIII but not FcRII or FcRI receptor with a monoclonal antibody ( 3G8 ) markedly reduced phagocytosis in the animals with intraabdominal sepsis . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
A flow cytometric analysis using anti FcRI , FcRII and FcRII monoclonal antibodies showed that IVIG treatment upregulated FcRI expression but did not significantly alter the expression of FcRII and FcRIII . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Human alveolar macrophage have three distinct receptors for IgG : FcRI , FcRII , and FcRIII . ^^^ We found alveolar macrophage readily lysed heteroantibody opsonized CE via each of the three FcR classes ( FcRI , 20 + / 5 % ; FcRII , 27 + / 7 % ; and FcRIII , 13 + / 13 % , p less than 0 . 05 ) . ^^^ No activity of FcRII or FcRIII was detected in these latter assays even if performed under conditions that impair FcRI activity . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Cytokine induced increases in both FcRI and FcRIII were not evident within the first hour of treatment suggesting that these molecules are not available in an intracellular compartment but must be newly synthesized . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
They fall into three distinct classes ( FcRI , FcRII , FcRIII ) based upon a number of criteria including molecular size , affinity , and specificity for ligand , cell specific display , and epitope expression ; but with a few possible exceptions these three classes do not seem to correlate with the multiple functional properties of the receptors . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The addition of monoclonal antibody to the Fc receptor 3 ( anti FcRIII ) , but not of antibodies that react with FcRI or FcRII , inhibited HIV type 1 and HIV type 2 enhancement in peripheral blood macrophages . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three classes of FcR have been defined on human myeloid cells by their reactivity with mAb ; FcRI ( mAb 32 ) ; FcRII ( mAb IV 3 ) ; and FcRIII ( mAb 3G8 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Three types of receptor for the Fc ( constant ) region of human immunoglobulin G have been described ; FcRI , a high affinity ( Ka approximately equal to 10 ( 8 ) M 1 ) receptor expressed on monocytes ; FcRII ( CD 32 ) , a low affinity ( Ka approximately equal to 10 ( 6 ) M 1 ) receptor expressed on B cells , granulocytes , macrophages and platelets ; and FcRIII ( CD 16 , FcRIo ) , a low affinity receptor expressed on macrophages , neutrophils , eosinophils , natural killer cells and a subset of T cells believed to comprise the suppressor cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The interstitial DCs expressed the LFA 1 antigen but failed to stain with CD11b , CD11c , and the defined T and B cell CD antibodies ; nor did they stain with antibodies to FcR 1 , FcR 11 , FcRIII , or the C3b receptor . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Lymphokine rich mouse spleen cell supernatants which contained natural IFN gamma again enhanced the FcRI expression , but did not modulate the expressions of FcRII or FcRIII in vitro . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
FcRI , FcRII and FcRIII were expressed on stomal cells throughout the cycle . ^^^ The endothelium was negative in the midcycle and positive early and late in the cycle for FcRI and FcRIII , although weak for FcRIII late in the cycle . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Flow cytometry was used to quantitate FcRIII [ cluster of differention ( CD ) 16 ] , FcRII ( CD 32 ) , FcRI ( CD 64 ) , CD 14 , and CD 67 proteins on the PMN surface . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We found a reduction in receptor expression with the percentage of cells expressing FcRI 14 days post infection declining from 77 % to 13 % , FcRII fell from 96 % to 85 % , FcRIII from 45 % to 9 % , and CR 3 from 91 % to 67 % 14 days following infection . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Receptors for the Fc part of IgG , FcRI ( CD 64 ) , FcRII ( CD 32 ) , and FcRIII ( CD 16 ) were studied by indirect immunoperoxidase staining of cryostat sections from normal and multiple sclerosis ( MS ) brains . ^^^ Microglia in the parenchyma of normal white matter had a dendritic morphology , and were weakly stained by monoclonal antibodies ( mAbs ) to FcRI , FcRII , and FcRIII . ^^^ In active MS lesions reactive microglia were strongly stained by the mAbs 32 . 2 ( FcRI ) , 4 3 ( FcRII ) , and 3G8 ( FcRIII ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc receptor ( FcR ) mediated phagocytosis and FcR ( FcRI , FcRII and FcRIII ) membrane expression was studied on freshly separated and cultured monocytes ( Mo ) from 20 AIDS patients and 20 healthy controls . ^^^ In fact , the percentages of phagocytes reacting with anti FcRI MoAb ( 32 . 2 ) or anti FcRII MoAb ( IV . 3 ) were similar for controls and AIDS patients , while the percentage of FcRIII positive Mo ( MoAb 3G8 ) was higher in the AIDS population than in controls , though this difference was not seen on cultured Mo . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
On the other hand , the administration of G CSF increased the expression of CR 1 , CR 3 , FcRI and FcRIII on monocytes . ^^^ The expression of CR 1 , CR 3 and FcRI on monocytes then decreased after the last G CSF administration , whereas the expression of FcRIII remained at an increased level . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Before operation , the expression of FcRI and CR 1 was increased but the expression of FcRIII and L selectin was reduced in the patient . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
G CSF administration increased the expression of FcRI , FcRII , and CR 1 on neutrophils and decreased the expression of FcRIII on neutrophils in both groups . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We have examined the expression of the IgG Fc receptors ( FcRI , FcRII , FcRIII ) and complement receptors ( CR 1 , CR 3 ) in neutrophils from 42 patients with febrile bacterial infection , 20 patients with febrile viral infection and 69 non febrile healthy individuals . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Consistent with previous analyses of mast cells from other tissues , UMC expressed HLA class 1 , IgE , c kit receptor , CD 9 , CD 33 , CD 43 , CD 45 , and CD 54 , while CD11a , CD11b , CD 14 , CD 16 , CD 23 , and CD 64 were not detected . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
During GM CSF treatment there was also a significant increase in FcRI+ ( CD 64 ) , FcRII+ ( CD 32 ) , FcRIII+ ( CD 16 ) and CD14+ cells but not of CD56+ cells . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Monocytes constitutively express Fc receptor ( FcR ) for IgG type 1 ( CD 64 ) and type 2 ( CD 32 ) , but not type 3 ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Furthermore , CD 64 monocytes show significantly higher expression of CD45RA and Fc gamma receptor 3 ( CD 16 ) than CD64+ monocytes , but lack the natural killer cell markers CD 56 and CD 57 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Unlike CD56+ NK cells in peripheral blood , decidual CD56+ cells lack type 3 Fc receptors ( CD 16 ) and did not express significant levels of either type 1 FcR ( CD 64 ) or type 2 FcR ( CDw 32 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Compared to regular monocytes , mature monocytes had lower levels of the high affinity Fc gamma receptor 1 ( CD 64 ) , complement receptor 3 ( CD11b ) , CD45RO and higher levels for HLA DR , LFA 1 ( CD11a / CD18 ) , interleukin 2 receptor ( CD 25 ) , CD45RA and the Fc gamma receptor 3 ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Like IL 4 , it enhanced the expression of CD11b , CD11c , CD 18 , CD 29 , CD49e ( VLA 5 ) , class 2 MHC , CD 13 , and CD 23 , whereas it decreased the expression of CD 64 , CD 32 , CD 16 , and CD 14 in a dose dependent manner . ^^^ IL 13 induced up regulation of class 2 MHC Ag and its down regulatory effects on CD 64 , CD 32 , and CD 16 expression were prevented by IL 10 . ^^^ IFN gamma could also partially prevent the IL 13 induced down regulation of CD 64 , but not that of CD 32 and CD 16 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Anti Fc gamma RIII ( CD 16 ) , anti Fc gamma RII ( CD 32 ) , and anti Fc gamma RI ( CD 64 ) had no blocking effect on IL 1ra production from monocytes after IgG stimulation . ^^^ Monocytes express Fc gamma RI and 2 and respond as anti CD 32 to secrete IL 1ra ; neutrophils express Fc gamma RII and 3 and respond as anti CD 16 to secrete IL 1ra ; macrophages express Fc gamma RI , 2 , and 3 and respond as both anti CD 16 and anti CD 32 to secrete IL 1ra . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Intimal MPs expressed a wide range of macrophage associated antigens , including receptors for Fc ( CD 16 , CD 32 , CD 64 ) and complement ( CD 35 , CD11b , CD11c ) as well as several integrin and non integrin cell adhesion molecules ( CD29 / CD49b , CD49d , CD49f , CD51 / CD61 , CD11a , CD 31 , CD 54 , CD 44 , CD 9 , CD 63 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Polymorphonuclear leukocytes ( PMN ) were incubated with LPS ( 10 ng / ml ) , permeabilized with saponin , followed by measurement of CD 64 , CD32w , and CD 16 ( Fc gamma RI , 2 , 3 ) using 125I monoclonal antibodies directed against these receptors . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
PMN adherence , superoxide anion production , 3 ( 4 , 5 dimethylthiazol 2 yl ) 2 , 5 diphenyltetrazolium bromide ( MTT ) formazan production , and surface receptor expression ( CD 64 , CD32w , CD 16 , CD 35 , and CD11b / CD18 ) using monoclonal antibodies directed against these receptors were assayed . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
On the basis of molecular weight , MAB S7G8 and S8G10 are comparable to human CD 15 , CD 16 , and CD 64 molecules . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Association of all three types of Fc gamma R ( CD 64 , CD 32 , and CD 16 ) with a gamma chain homodimer in cultured human monocytes . ^^^ We found that all three types of Fc gamma R ( CD 64 , CD 32 , and CD 16 ) in cultured human monocytes are associated with the gamma chain homodimer that is also present in the high affinity receptor for IgE . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Tissue distribution of human IgG Fc receptors CD 16 , CD 32 and CD 64 : an immunohistochemical study . ^^^ The tissue distribution of human IgG Fc receptors ( Fc gamma Rs ) classified in three clusters of differentiation ( CD 16 , using 5 antibodies , CD 32 , using 2 antibodies ; and CD 64 , using 3 antibodies ) was evaluated by immunohistochemistry on lymphoid ( lymph node , spleen , thymus , tonsil ) and non lymphoid ( heart , jejunum , kidney , liver , lung , muscle , stomach , and skin ) tissues . ^^^ Interdigitating dendritic cells that were present in high density in interfollicular areas of a lymph node showing dermatopathic lymphadenopathy were immunoreactive for CD 32 , but not for CD 16 or CD 64 antibodies . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Finally , IL 10 decreased HLA DR expression and increased the expression of the Fc gamma receptors , CD 16 and CD 64 , by SF macrophages . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The HSV IPC expression of CD 13 , CD 33 and Fc epsilon RI were weak but significant , while no CD 5 , CD11b , CD 16 , CD 64 , CD 80 or CD 86 were detected . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Recombinant IL 13 significantly reduced the production of IL 1 beta and tumor necrosis factor alpha and the expression of CD 16 and CD 64 by SF macrophages , whereas the expression of HLA DR and CD 23 was increased . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Long term continuous ambulatory peritoneal dialysis reduces the expression of CD11b , CD 14 , CD 16 , and CD 64 on peritoneal macrophages . ^^^ RESULTS : Flow cytometry analysis revealed that the expression of CD11b , CD 16 , CD 64 , and CD 14 on NPE macrophages was reduced during the course of CAPD treatment , reaching levels which represented a 40 % 50 % reduction of the cell surface expression detected at the start of the treatment or on normal control macrophages . ^^^ CONCLUSION : Our results show that long term CAPD might affect Fc gamma receptor mediated phagocytosis by reducing the expression of CD 16 , CD 64 , and CD11b . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The tumor cells expressed surface IgG , CD 10 , CD 19 and CD 20 , but not surface IgM , IgD , IgA , CD 5 , CD 16 , CD 32 and CD 64 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Whole blood PMN were rendered hypoxemic ( venous PO 2 < 15 mmHg ) , normoxic ( venous PO 2 60 80 mmHg ) , or reoxygenated after hypoxemia ( H / R = venous PO 2 150 200 mmHg ) and were incubated with IL 8 , TNF alpha , or IL 1beta before sequential addition of serum opsonized fluorescent microspheres and fluorescein isothiocyanate conjugated mouse anti human CD 64 , CD32w , CD 16 , CD 35 , or CD11b / CD18 . ^^^ During reoxygenation , both whole blood PMN phagocytosis and bactericidal activity were reduced in the presence of IL 8 , TNF alpha , or IL 1beta , and in subsets of PMN with reduced phagocytosis H / R reduced CD 64 , CD32w , CD 16 , CD 35 , and CD11b / CD18 expression in the presence of each cytokine . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
PMNL GCSF CFL showed decay in CD11b ( CR 3 ) , CD 16 ( Fc gamma 3 ) and CD 64 ( Fc gamma R 1 ) expression after 20 h in cell culture , but treatment with IFN gamma + G CSF preserved expression . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
K1m also expresses Fc receptors for immunoglobulin G ( IgG ) ( CD 64 , CD 32 , and CD 16 ) and can be shown to phagocytose polystyrene latex beads , as well as neuroblastoma cells in the presence of tumour specific monoclonal antibody ( mAb ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
To analyze the specificity of the affinity purified autoantibody , cells ( human neutrophils , IFN gamma stimulated neutrophils , monocytes , and the THP 1 monocytic cell line ) that express different combinations of Fc gamma R ( CD 64 , CD 32 , CD 16 ) were stained with the affinity purified Ig . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
TNF alpha or IL 1beta did not change the expression of CD 9 , CD 13 , CD 16 , CD 23 , CD 29 , CD 31 , CD 32 , CD 35 , CD 45 , CD 61 , or CD 64 in BEAS 2B cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Treatment increased expression of CD11b / CD18 but not Fcgamma receptors ( CD 16 , CD 32 , CD 64 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Flow cytometry studies using CD 16 , CD 32 and CD 64 monoclonal antibodies showed a sharp reduction on the expression of CD 64 ( Fc gamma RI ) both by human monocyte derived macrophages and THP 1 cells after incubation with LDL IC , suggesting preferential engagement of this type of Fc receptor . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Neutrophils from 13 children who received G CSF for the collection of peripheral blood progenitors while they were in haematological steady state were studied at various times after G CSF injection for Fc gammaR expression ( Fc gammaRI or CD 64 , Fc gammaRII or CD 32 , and Fc gammaRIII or CD 16 ) and for their ability to exert antibody dependent cell cytotoxicity ( ADCC ) through Fc gammaRI . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
DCs were identified by flow cytometry as mononuclear leucocytes with the phenotype HLA DR+ , CD 2 , CD 16 , CD 19 , CD 57 , and either CD 14 or CD 64 and hence are described herein as either CD 14 DCs or CD 64 DCs , respectively . ^^^ We conclude that mononuclear cells with the phenotype HLA DR+ , CD 3 , CD 16 , CD 19 , CD 56 , and CD 64 are blood DCs that may be CD14+ or CD 14 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Expression of MHC class 1 , CD 16 ( low affinity Fc receptor for aggregated IgG ) , CD 32 ( low affinity Fc receptor for aggregated IgG ) , CD 64 ( high affinity receptor for IgG ) , CD11b ( receptor for complement component iC3b [ CR 3 ] ) , CD 35 ( receptor for complement components C3b and C4b [ CR 1 ] ) , and CD 36 ( non class A scavenger receptor ) was not specifically affected by hemozoin loading . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Flow cytometric triple fluorescence analysis was applied to study CD 14 , CD 16 , CD 33 , CD 44 , CD11b , CD11c , CD 64 , HLA DR , CD 80 , CD 86 and CD3 / CD19 expression . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
RESULTS : The expression of L selectin ( CD62L ) , Fcgamma receptor ( FcgammaR ) 3 ( FcgammaRIII , CD 16 ) , and the leukocyte function antigen ( CD11a ) decreased throughout the course of G CSF administration , while the expression of FgammaR 1 ( FcgammaRI , CD 64 ) and lipopolysaccharide binding protein receptor ( CD 14 ) increased . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Addition of recombinant IL 10 to DC cultures enhanced c fms expression and induced macrophage development as measured by the strong up regulation of CD 14 expression as well as by enhanced expression of the Fcgamma receptors 1 , 2 , and 3 ( CD 64 , CD 32 , CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
To determine if the monocytes observed during the acute stage were phenotypically altered , they were periodically examined for the expression of surface markers ( i . e . , CD11b , CD 14 , CD 16 , CD 29 , D 32 , CD 56 , CD62L , CD 64 , CD 80 , and MHC 2 DR ) by flow cytometry . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
METHODS : Fluorescence activated cell sorter analysis was used to measure the changes in antigen expression ( CD11b / c , CD 16 , CD 64 , CD 14 , CD 68 , and CD 95 ) in response to MTX , 1 , 25 OH cholecalciferol ( 1 , 25 OH CCF ) , and granulocyte macrophage colony stimulating factor in the human monoblastic leukemia cell line U 937 , bone marrow mononuclear cells ( BMMC ) , and peripheral blood mononuclear cells ( PBMC ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Phagocyte functions were studied by measuring the chemiluminescence ( CL ) activity of whole blood and isolated leucocytes and by investigating the expression of phagocyte receptors ( FcgammaRI ( CD 64 ) , FcgammaRII ( CD 32 ) , FcgammaRIII ( CD 16 ) , CR 1 ( CD 35 ) , CR 3 ( CD11b ) and FcalphaR ( CD 89 ) ) on neutrophils , monocytes and eosinophils by using receptor specific MoAbs and immunofluorescence flow cytometry . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
CD 16 , CD 32 , and CD 64 molecules on PMNL were evaluated by cytofluorometric analysis . ^^^ Expression of CD 16 , and to a lesser extent CD 64 , on PMNL was required for MAb18B7 induced superoxide generation . ^^^ By blocking CD 16 and CD 64 molecules with anti CD 16 and anti CD 64 MAb , a significant down regulation of MAb18B7 induced fungicidal activity was observed . ^^^ The availability of CD 16 and CD 64 molecules on PMNL plays a critical role . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
During ex vivo expansion of CD34+ cells isolated from human CB for up to 5 weeks , surface expression of molecules on the cultured cells including CD 64 ( Fc gammaRI ) , CD 32 ( Fc gammaRII ) , CD 16 ( Fc gammaRII ) , CD11b ( MAC 1 ) and CD 18 ( beta 2 integrin ) was analysed by flow cytometry along with simultaneous measurement of apoptosis by 7 aminoactinomycin D staining method . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Our results showed increased expression of FcgammaRI ( CD 64 ) and FcgammaRIII ( CD 16 ) in acutely inflamed skin as well as in chronically inflamed lesional skin , compared with healthy and non lesional atopic dermatitis skin . ^^^ The significant increase in expression of FcgammaRIII ( CD 16 ) and FcgammaRI ( CD 64 ) probably results from upregulation of the receptors on resident cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Human MO subsets as defined by expression of CD 64 and CD 16 differ in phagocytic activity and generation of oxygen intermediates . ^^^ Recently , we could show that each subset itself further differs in the expression of the Fc gamma receptor 3 ( CD 16 ) and T cell accessory activities resulting in four different subsets : two CD16+ subsets ( CD64+ or CD 64 ) with high T cell stimulation capacity and two CD 16 subsets ( CD64+ or CD 64 ) with low accessory activities . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Human IL 10 stimulated CD 16 and CD 64 expression on the monocyte / macrophage population within peripheral blood mononuclear cells , with optimal concentrations between 1 and 10 ng / mL . ^^^ Soluble heparin , heparan sulfate , chondroitin sulfate , and dermatan sulfate were shown to inhibit the hIL 10 induced expression of CD 16 and CD 64 in a concentration dependent manner . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Further , superoxide anion production and Fc gammaRI ( CD 64 ) expression were found to be significantly increased and Fc gammaRII ( CD 16 ) expression was lowered . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In parallel , the expression by monocytes of co stimulatory molecules ( CD 40 , CD 80 , CD 86 ) , major histocompatibility complex molecules ( HLA ABC , HLA DR ) and Fcgamma receptors ( CD 16 , CD 64 ) was examined by flow cytometry . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Monoclonal antibodies directed to FcgammaRII ( CD 32 ) were also inhibitory , whereas antibodies to the two other classes of Fcgamma receptors , CD 16 and CD 64 , were not . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
When mixed with Ad expressing eGFP , CARex Fc mediated an up to 250 fold increase of transgene expression in CAR negative human monocytic cell lines expressing the high affinity Fcgamma receptor 1 ( CD 64 ) but not in cells expressing the low affinity Fcgamma receptor 2 ( CD 32 ) or 3 ( CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
BMs obtained by induced sputum from mild asthmatics ( n = 20 ) and healthy individuals ( n = 20 ) were analyzed using flow cytometry for CD 16 , CD 64 , CD11b , CD 14 , and human leukocyte antigen DR expression , phagocytosis of IgG opsonized yeast , and oxidant production . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Identification of a novel dendritic cell like subset of CD 64 ( + ) / CD 16 ( + ) blood monocytes . ^^^ Double labeling with anti CD 64 and anti CD 16 mAb , as performed here , identified four different subsets . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We investigated Fc receptor dependent tumor cell killing by mononuclear and granulocytic effector cells comparing human IgG 1 antibodies against CD 20 or HER 2 / neu with their respective FcgammaRI ( CD 64 ) , FcgammaRIII ( CD 16 ) , or FcalphaRI ( CD 89 ) directed bispecific derivatives . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
METHODS : As part of two randomized , double blinded , placebo controlled trials , repeated flow cytometric analyses of lymphocyte phenotypes ( CD 3 , CD 4 , CD 8 , CD 16 + 56 , CD 19 ) and activity markers ( human leukocyte antigen [ HLA ] DR ; intercellular adhesion molecule 1 [ ICAM 1 ] ; IL 2 receptor alpha [ IL 2R alpha ] ; high affinity receptor for immunoglobulin G [ IgG ; Fc gamma RI ] ) on T cells , monocytes , and neutrophils were performed in 17 patients with IBD who received rHuIL 10 ( 5 , 10 , or 20 micrograms / kg ) or placebo , administered subcutaneously , once daily for 28 days . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We compared expression of monocyte CD 23 with expression of monocyte Fcgamma receptors ( CD 16 , CD 32 , CD 64 ) , plasma / serum levels of IgE ( also IgM , IgG , IgA ) , and Th 1 ( IFN gamma ) and Th 2 ( IL 4 , IL 10 ) cytokines . ^^^ We found that monocyte CD 23 expression directly correlated with monocyte CD 16 expression ( p < 0 . 01 , R = 0 . 58 ) , which was also increased in AIDS patients ; there was no correlation with CD 32 or CD 64 or with soluble factors in plasma / serum ( i . e . , IgE , IL 4 , IL 10 , and IFN gamma ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Normal human PB CD 16 ( + ) / HLA DR ( + ) cells also displayed phenotypic characteristics different from those of CD 14 ( + ) monocytes : they lacked the CD 64 Fcgamma receptor , showed lower levels of CD 32 , and expressed higher amounts of CD 16 compared to CD 14 ( + ) monocytes . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Particle inhalation did not affect the expression of CD11b , CD 64 , CD 16 , CD 14 , CD 71 on AM , nor was there an effect on phagocytosis or oxidant generation following stimulation with zymosan A . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The are three major types of Fcgamma R , namely Fcgamma RI ( CD 64 ) , Fcgamma RII ( CD 32 ) and Fcgamma RIII ( CD 16 ) , and these differ in their ability to bind IgG and complexes . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The panel of antibodies included CD11b , CD 14 , CD 16 , CD 18 , CD49d , CD62L , CD 64 , CD66b , and HLA DR . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
They expressed CD 4 , CD11a , CD11b , CD11c , CD 18 , CD 32 , CD 33 , CD45R0 , CD 48 , CD 50 , CD 54 , CD 58 , CD 64 , CD 86 , CD 102 , CD 116 , CD 123 , and HLA DR ; showed no expression of CD1a and CD 83 ; and weak expression of CD 16 , CD45RA , and CD 80 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Phenotypic and metabolic characteristics of monocytes and granulocytes were studied with the use of flow cytometry and monoclonal antibodies against surface markers ( CD11b , CD 14 , CD 15 , CD 16 , CD 18 , CD49d , CD62L , CD 64 , CD66b , and HLA DR ) . ^^^ RESULTS : Granulocytes from normal pregnant women had a higher median mean channel brightness for CD 14 and CD 64 , but lower median mean channel brightness for CD 16 and HLA DR than granulocytes of nonpregnant women . ^^^ Monocytes from patients with acute infection had a higher mean channel brightness for CD11b , CD 16 , CD 18 , CD49d , CD 64 , and CD66b than monocytes of normal pregnant women . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Maternal blood was assayed to determine granulocyte and monocyte phenotype by using monoclonal antibodies , which included the following cluster of differentiation ( CD ) markers : CD11b , CD 14 , CD 15 , CD 16 , CD 18 , CD49d , CD62L , CD 64 , CD66b , and HLA DR . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The aberrant cells of patient 2 have the surface phenotype gammadeltaTCR + CD 19 + CD 14 CD 64 + CD 16 + CD 13 + CD 33 + . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Microbiological analysis of genital chlamydial infection in FcR knockout ( FcRKO ) mice lacking the activatory FcgammaRI ( CD 64 ) and FcRgammaIII ( CD 16 ) , as well as the inhibitory FcgammaRIIB 1 ( CD 32 ) , revealed a greater intensity of secondary infection ( i . e . bacterial shedding ) in FcRminus sign / minus sign as compared to FcR+ / + mice ; however , the course of the primary infection was indistinguishable in both animals . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In contrast , CD 14 was increased in a subpopulation of cells that expressed major histocompatibility ( MHC ) class 2 and PR 3 , but lacked expression of CD 64 and CD 16 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
This study examined phagocytosis as well as numerical expression of Fcgamma 1 3 ( CD 16 , CD 32 , CD 64 ) and complement receptors ( CD 18 , CD 35 ) of emigrated , intra abdominal and circulating neutrophils during human secondary peritonitis using fluorescence activated cell analysis . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Opsonization and phagocytosis was completely inhibited by blocking of C5aR or CR 3 , whereas blocking of the FcgammaRs ( CD 16 , CD 32 , CD 64 ) had no effect . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
RESULTS : During the exacerbation phase of AEDS , patients harboured a different assembly of Mo subtypes from normal nonatopic individuals and patients with psoriasis with a significant increased population of CD 14 ( + ) CD 64 ( ) CD 16 ( + ) Mo . ^^^ Clinical improvement led to a significant decrease of this subpopulation in favor of CD 14 ( + ) CD 64 ( + ) CD 16 ( ) Mo , leading to a composition of Mo subsets similar to the state found in healthy donors . ^^^ Interestingly , Fc epsilon RI expression was confined to the CD 14 ( + ) CD 64 ( + ) CD 16 ( ) Mo subpopulation and the percentage of this Fc epsilon RI ( + ) Mo subset increased significantly in the peripheral blood after topical treatment . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Maternal blood was assayed to determine granulocyte and monocyte phenotype using monoclonal antibodies , which included cluster differentiation ( CD ) markers CD11b , CD 14 , CD 15 , CD 16 , CD 18 , CD49d , CD62L , CD 64 , CD66b and human leukocyte antigen ( HLA ) DR . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Expression patterns of the lipopolysaccharide receptor CD 14 , and the FCgamma receptors CD 16 and CD 64 on polymorphonuclear neutrophils : data from patients with severe bacterial infections and lipopolysaccharide exposed cells . ^^^ We now report that in patients with severe bacterial infections , CD 14 expression is profoundly upregulated , as is CD 64 ( FcgammaRI ) , the high affinity receptor for IgG , whereas CD 16 ( FcgammaRIII ) was partly lost from the surface . ^^^ By brief exposure ( 10 120 min ) to LPS , CD 14 was transferred to the surface in a cytochalasin B sensitive manner , as were CD 16 and CD 64 . ^^^ Prolonged culture ( up to 48 h ) resulted in a further upregulation of CD 14 , sustained expression of CD 64 , and profound decline of CD 16 , yielding a similar pattern of receptor expression as seen in the patients . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In addition , cytocentrifuge macrophage preparations were stained with monoclonal antibodies against proteins indicating alternative ( anti inflammatory ) macrophage activation , such as MS 1 high molecular weight protein ( MS 1 HMWP ) , RM3 / 1 antigen ( CD 163 ) and 25F9 , as well as classical ( pro inflammatory ) macrophage activation , such as CD11c , class 1 receptor binding the Fc part of IgG ( FcgammaRI : CD 64 ) and class 3 receptor binding the Fc part of IgG ( FcgammaRIII : CD 16 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
These features link the possible identity of DLCs to that of an uncommon CD 14 ( + ) CD 16 ( + ) CD 64 ( ) monocyte subset found to be expanded in a variety of pathological conditions . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Pregnancy is associated with temporary changes in granulocytic surface markers , such as a lower expression of CD 16 and a higher CD 64 , partially mimicking an inflammatory response . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
A similar activation pattern was found : rapid down regulation of CD62L , a slower loss of CD 16 , and upregulation of CD 18 , CD 64 , and CD 14 . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Fc was able to modulate the expression of several macrophage markers , including CD 14 , CD 16 , CD 64 , and human leukocyte antigen DR . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
An excellent correlation was also identified between the sum of bands and segmented neutrophils and each of the following : CD 16 ( ++ ) ( strong positivity ) , CD 35 ( + ) , CD 87 ( + ) , and CD 64 ( ) . ^^^ A successful strategy for detecting maturation defects is to include several antibodies that are known to be expressed or absent at the same stage of maturation , such as CD 16 , CD 35 , CD 64 , and CD87 . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Surface expression of Fcgamma receptors RI ( CD 64 ) , RII ( CD 32 ) and RIII ( CD 16 ) , complement receptors CR 1 ( CD 35 ) and CR 3 ( CD11b / CD18 ) , and adhesion molecules ICAM 1 ( CD 54 ) and CD11a ( LFA 1 ) was determined . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
RESULTS : HR 8348 cell line did not express CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , TCR , CD 10 , CD11b , CD 14 , CD 16 , CD 19 , CD 22 , CD 25 , CD 28 , SmIg , CD 33 , CD 35 , CD 36 , CD41a , CD 45 , CD45RA , CD45RO , CD 56 , CD 61 , CD 64 , CD66b , CD 69 , CD 71 , CD 117 , CD 122 and P glycoprotein but expressed CD 13 , CD 15 , CD 20 , CD 38 , CD 95 and HLA DR . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The effect of TNF alpha neutralisation on the phenotype ( CD 14 , CD 16 , CD 32 , CD 64 , CD 80 , CD 83 , CD 86 , and MHC ) of dendritic cells was investigated by flow cytometry . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
White blood cells , isolated from EDTA blood by centrifugation after cell fixation with paraformaldehyde , were labelled with FITC conjugated CD 16 ( FcgammaRIII ) , CD 32 ( FcgammaRII ) , CD 64 ( FcgammaRI ) , CD11b ( CR 3 ) and CD 35 ( CR 1 ) monoclonal antibodies and analysed by flow cytometry . ^^^ Lymphocytes expressed CD 16 and CD 32 but not CD 64 . ^^^ CD 16 and CD 64 MFI were not different among the groups and CD 35 MFI was only lower on lymphocytes from PD , HD and CRF compared with HC . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Here we show that human intestinal macrophages do not express innate response receptors , including the receptors for LPS ( CD 14 ) , Fcalpha ( CD 89 ) , Fcgamma ( CD 64 , CD 32 , CD 16 ) , CR 3 ( CD11b / CD18 ) , and CR 4 ( CD11c / CD18 ) ; the growth factor receptors IL 2 ( CD 25 ) and IL 3 ( CD 123 ) ; and the integrin LFA 1 ( CD11a / CD18 ) . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
WBCs were isolated from blood and PDE , labelled with FITC conjugated CD 16 ( FcgammaRIII ) , CD 32 ( FcgammaRII ) , CD 64 ( FcgammaRI ) , CD11b ( CR 3 ) and CD 35 ( CR 1 ) monoclonal antibodies , and analysed by flow cytometry . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Also , preincubation with anti CD 32 and CD 64 antibodies significantly inhibited maximal binding of CRP to HAECs 64 % and 30 % , respectively , whereas antibodies to CD 16 had no effect . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
RESULTS : Human retinal microglia expressed detectable levels of CD 4 , CD 16 , CD 64 , and CCR 5 in vitro and Fcgamma receptor 1 ( CD 64 ) in situ . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
In addition , receptors associated with activation / apoptotis ( CD11b , CD 64 , tumor necrosis factor receptor , and Fas ligand ) are up regulated , together with a loss of CD 16 expression . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Blocking of Fc gammaRI ( CD 64 ) , Fc gammaRII ( CD 32 ) , and Fc gammaRIII ( CD 16 ) individually or together also reduced neutrophil uptake of AdLuc , although less than blocking of CD 35 alone . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
RESULTS : Surface expression of CD11b / CD18 , CD 14 , CD 16 , CD 32 , and CD 64 was maintained during 48 hour storage at reduced temperature . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Expression of raft associated antigens ( CD11b , CD 13 , CD 14 , CD 16 , CD 36 , and CD 64 ) was followed by flow cytometry and / or immunoblot in human monocyte derived macrophages in response to in vitro administration of Ezetimib . ^^^ Ezetimib significantly decreased the surface expression of CD 13 , CD 16 , CD 64 , and CD 36 ; furthermore , it induced a shift of CD 13 from plasma membrane to intracellular vesicles , and thus it quite likely modulated monocytic raft assembly . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Preincubation with antibodies to CD 32 and CD 64 but not CD 16 effectively inhibited this activation . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
An extensive series of Mab ( CD 2 , CD 3 , CD 4 , CD 8 , CD11b , CD 13 , CD 14 , CD 16 , CD 19 , CD 22 , CD 33 , CD 34 , CD 41 , CD42b , CD 45 , CD 56 , CD 61 , CD 64 , CD235a and HLA DR ) were tested singly or in FITC / PE combinations . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
The proportion of monocytes that expressed CD62L , HLA DR , CD 16 , CD 64 , and CD 40 varied during the course of infection in macaques that eventually developed encephalitis . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
We examined the expression of FcgammaR ( CD 32 , CD 16 and CD 64 ) and compared the effect of anti CD 32 antibody on the viability of myeloma cells to that on the viability of normal plasma cells . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Mining of the catfish expressed sequence tag databases using mammalian FcR sequences for CD 16 , CD 32 , and CD 64 resulted in the identification of a teleost Ig binding receptor . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Among the 18 commonly decreased transcripts in both PBMC and purified monocytes , we selected six genes , FCGR1A , FCGR3A , CCR 2 , ADM , S100A9 , and S100A12 , and confirmed the microarray results by real time RT PCR . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
Interestingly , activated DCs lacked expression of the CD 16 and CD 64 Fc gammaR , which may have important implications for exogenous antigen loading strategies . . ^^^
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA
Interacting proteins: P08637 and P12314	Pubmed	SVM Score :0.0
NA