Using the QXP and GOLD programs , we compared the ability of six single scoring functions ( PLP , Ligscore , Ludi , Jain , ChemScore , PMF ) and four composite scoring models ( Mean Rank : MR , Rank by Vote : Vt , Bayesian Statistics : BS and PLS Discriminant Analysis : DA ) to separate compounds that are active against CDK 2 from inactives . ^^^