| Interacting proteins: Q99700 and P11940 |
Pubmed |
SVM Score :0.0 |
| We found that the C . elegans ortholog of ataxin 2 , ATX 2 , forms a complex with PAB 1 , a cytoplasmic polyA binding protein , and that ATX 2 is required for development of the germline . ^^^ |
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| Interacting proteins: Q99700 and P11940 |
Pubmed |
SVM Score :0.0 |
| Here , we demonstrate that ataxin 2 and its Drosophila homolog , ATX 2 , assemble with polyribosomes and poly ( A ) binding protein ( PABP ) , a key regulator of mRNA translation . ^^^ |
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| Interacting proteins: Q99700 and P11940 |
Pubmed |
SVM Score :0.0 |
| The functional relationship of ATX 2 and Pbp 1 is further corroborated by the experimental confirmation of the predicted interaction of ATX 2 with the cytoplasmic poly ( A ) binding protein 1 ( PABP ) using yeast 2 hybrid analysis as well as co immunoprecipitation experiments . ^^^ Immunofluorescence studies revealed that ATX 2 and PABP co localize in mammalian cells , remarkably , even under conditions in which PABP accumulates in distinct cytoplasmic foci representing sites of mRNA triage . . ^^^ |
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| Interacting proteins: Q99700 and P11940 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99700 and P11940 |
Pubmed |
SVM Score :0.0 |
| NA |
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