| Interacting proteins: O43432 and P11940 |
Pubmed |
SVM Score :0.0 |
| The 29 amino acid stretch is almost identical in eIF4GI and eIF4GII , and the full length eIF4GII also binds PABP . ^^^ |
|
| Interacting proteins: O43432 and P11940 |
Pubmed |
SVM Score :0.0 |
| In addition to cleavage of eIF4GI , cleavage of eIF4GII and poly ( A ) binding protein ( PABP ) has been recently proposed to contribute to complete host translation shutoff ; however , the relative importance of eIF4GII and PABP cleavage has not been determined . ^^^ |
|
| Interacting proteins: O43432 and P11940 |
Pubmed |
SVM Score :0.0 |
| In HeLa cell translation extracts that exhibit cap poly ( A ) synergy , partial cleavage of PABP by 3Cpro inhibited translation of endogenous mRNAs and reporter RNA as effectively as complete cleavage of eIF4GI and eIF4GII by 2Apro . 3Cpro mediated translation inhibition was poly ( A ) dependent , and addition of PABP to extracts restored translation . ^^^ |
|