| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| When reconsituted with NADPH cytochrome P 450 reductase and L alpha dilauroyl sn glyceryo 3 phosphocholine , P 450MP 1 and P 450MP 2 gave apparently higher turnover numbers for mephenytoin 4 hydroxylation than did the P 450 in the microsomes . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| Phenytoin induced activity in NADPH cytochrome P 450 reductase , CYP3A , CYP2B , and CYP2C that was 3 to 4 times higher than that of the controls . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| Oral treatment with alpha tocopherol for 4 days dose dependently increased the content of cytochrome P 450 ( CYP ) , catalytic activities of CYP1A1 , CYP1A2 , CYP2B1 , CYP2C , and activity of NADPH cytochrome P 450 reductase in the liver of male rats , but did not change activity of glutathione S transferase . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| Recombinant CYP2C8 , CYP2C19 , two allelic variants of CYP2C18 , and six variants of CYP2C9 expressed in a yeast cDNA expression system were each enzymatically active , as judged by the ability of the isolated microsomes to catalyse 7 ethoxycoumarin O deethylation after reconstitution with purified NADPH cytochrome P 450 reductase and cytochrome b 5 . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| A series of Salmonella typhimurium ( S . typhimurium ) YG 7108 strains , each coexpressing a form of human cytochrome P 450 ( CYP ) ( CYP1A1 , CYP1A2 , CYP1B1 , CYP2C8 , CYP2C9 , CYP2C19 , CYP2D6 , CYP3A4 , or CYP3A5 ) together with human NADPH cytochrome P 450 reductase ( OR ) , was established . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| The role of human cytochrome P 450 ( CYP ) in the metabolic activation of these tobacco related N nitrosamines was examined by a Salmonella mutation test using genetically engineered Salmonella typhimurium ( S . typhimurium ) YG 7108 cells each expressing a form of human CYP ( CYP1A1 , CYP1A2 , CYP1B1 , CYP2A6 , CYP2C8 , CYP2C9 , CYP2C19 , CYP2D6 , CYP2E1 , CYP3A4 , or CYP3A5 ) together with human NADPH cytochrome P 450 reductase . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| The role of human cytochrome P 450 ( CYP ) in the metabolic activation of tobacco related N nitrosamines was examined by Salmonella mutation test using a series of genetically engineered Salmonella typhimurium YG 7108 strains each co expressing a form of CYP ( CYP1A1 , CYP1A2 , CYP1B1 , CYP2A6 , CYP2C8 , CYP2C9 , CYP2C19 , CYP2D6 , CYP2E1 , CYP3A4 , and CYP3A5 ) together with human NADPH cytochrome P 450 reductase . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| Methods for the co expression in Escherichia coli of human cytochrome P 450 ( CYP ) 2C8 and CYP2C9 with NADPH cytochrome P 450 reductase ( OxR ) to produce a catalytically active system were compared . 2 . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| The current study examines whether the lack of methoxychlor O demethylation by CYP2C19 in HLM was due to CYP2C19 exhibiting inferior competition for the NADPH cytochrome P 450 reductase ( CPR ) versus CYP2C9 and explores the interactions between CYP2C9 and CYP2C19 in a singular and binary complex of a reconstituted system . ^^^ When reconstituted with CPR , cytochrome b ( 5 ) , and lipid , purified CYP2C19 and CYP2C9 catalyzed methoxychlor O demethylation . ^^^ However , whereas equimolar CPR to CYP2C9 supported maximal rates of methoxychlor demethylation and diclofenac hydroxylation , the rate of methoxychlor demethylation by CYP2C19 was not fully saturated , even with a 9 fold molar excess of CPR over CYP2C19 . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| Meanwhile , the levels of autoantibodies against CYP1A2 , CYP2A6 , CYP2C9 , UGT2B7 , MDR 1 and NADPH cytochrome P 450 reductase were 2 2 ( 2 ) higher in Patients 3 and 4 than in the other subjects . ^^^ |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P11712 and P16435 |
Pubmed |
SVM Score :0.0 |
| NA |
|