| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| Sequence alignments including this second dystrobrevin strongly support the concept that two distinct subfamilies exist within the dystrophin family , one composed of dystrophin , utrophin , and DRP 2 and the other composed of alpha and beta dystrobrevin . ^^^ A beta dystrobrevin antibody recognized a protein of the predicted size ( 71 kDa ) that copurified with the dystrophin short form , Dp 71 . ^^^ Thus , like alpha dystrobrevin , beta dystrobrevin is likely to associate directly with dystrophin . alpha and beta dystrobrevins failed to copurify with each other , however . ^^^ |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| Here we describe the characterization of beta dystrobrevin , a dystrophin related protein that is abundantly expressed in brain and other tissues , but is not found in muscle . beta dystrobrevin is encoded by a 2 . 5 kb alternatively spliced transcript that is found throughout the brain . ^^^ In common with dystrophin , beta dystrobrevin is found in neurons of the cortex and hippocampal formation but is not found in the brain microvasculature . ^^^ In the brain , beta dystrobrevin coimmunoprecipitates with the dystrophin isoforms Dp 71 and Dp 140 . ^^^ |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| To determine the composition of DPC like complexes in brain , we have examined the molecular associations and distribution of the dystrobrevins , a widely expressed family of dystrophin associated proteins , some of which are components of the muscle DPC . beta Dystrobrevin is found in neurons and is highly enriched in postsynaptic densities ( PSDs ) . ^^^ Furthermore , beta dystrobrevin forms a specific complex with dystrophin and syntrophin . ^^^ |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| Dystrobrevin is a newly discovered dystrophin associated protein that is classified as alpha and beta dystrobrevin . ^^^ |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| Role of beta dystrobrevin in nonmuscle dystrophin associated protein complex like complexes in kidney and liver . beta Dystrobrevin is a dystrophin related and associated protein that is highly expressed in brain , kidney , and liver . ^^^ Recent studies with the kidneys of the mdx3Cv mouse , which lacks all dystrophin isoforms , suggest that beta dystrobrevin , and not the dystrophin isoforms , may be the key component in the assembly of complexes similar to the muscle dystrophin associated protein complexes ( DPC ) in nonmuscle tissues . ^^^ |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| Transcripts for the full length dystrophin , Dp 427 , and the short isoform , Dp 71 , as well as for alpha dystrobrevin 2 increased in parallel with days in culture after RA stimulation , while dystroglycan , alpha dystrobrevin 1 and 3 , and beta dystrobrevin were constitutively expressed . ^^^ |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| Immunostaining studies indicate that DTN B and DTN expression is absent in affected muscle fibers from DMD patients and carriers . . ^^^ Sequence analysis indicates that this gene , named DTN B , is highly homologous to the rabbit A 0 , the previously described dystrobrevin ( DTN ) , Torpedo 87 kDa and to the C terminus of dystrophin . ^^^ |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60941 and P11532 |
Pubmed |
SVM Score :0.0 |
| NA |
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