| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| Recently , we found that ERG , an Ets family member , activates collagenase 1 gene but not stromelysin 1 by physically interacting with c Fos / c Jun . ^^^ We found that ETS 2 could weakly associate with in vitro synthesized ETS 1 , c Fos , and c Jun and strongly with c Fos / c Jun complex and ERG via several distinct ETS 2 domains including the C terminal region that contains the DNA binding domain . ^^^ Using the two hybrid system , we also demonstrated that ETS 2 interacts with c Jun or ERG in vivo . . ^^^ |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| Synergistic binding was observed in EMSA between AP 1 on the one hand , FLI 1 , ERG , and ETS 1 protein on the other . ^^^ |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| Identification of amino acid residues in the ETS transcription factor Erg that mediate Erg Jun / Fos DNA ternary complex formation . ^^^ To support the model , different Erg ETS domain mutants were obtained by deletion or by single amino acid substitutions and were tested for their ability to mediate DNA binding , Erg Jun / Fos complex formation , and transcriptional activation . ^^^ We identified point mutations that affect both the DNA binding properties of Erg and its physical interaction with Jun ( R367K ) , as well as mutations that essentially prevent transcriptional synergy with the Jun / Fos heterodimer ( Y371V ) . ^^^ |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| Imaging Erg and Jun transcription factor interaction in living cells using fluorescence resonance energy transfer analyses . ^^^ Previous in vitro studies have shown a transcriptional synergy between Erg protein , an Ets family member , and Jun / Fos heterodimer , members of the bZip family , which requires direct Erg Jun protein interactions . ^^^ For this purpose , we generated fusion proteins of Erg , Fos , and Jun with yellow and cyan fluorescent proteins , YFP and CFP , respectively . ^^^ FRET between YFP Erg and CFP Jun was monitored by using photobleaching FRET and fluorescence lifetime imaging microscopy . ^^^ Both techniques revealed the occurrence of intermolecular FRET between YFP Erg and CFP Jun . ^^^ |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| Here we show that those Ets family proteins that participate in Ewing ' s sarcoma , including Fli 1 , ERG , and ETV 1 , cooperatively bind these tandem elements with Fos Jun while other Ets family members do not . ^^^ |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P11308 and P05412 |
Pubmed |
SVM Score :0.0 |
| NA |
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