| Interacting proteins: Q13322 and P11274 |
Pubmed |
SVM Score :0.0 |
| The SH 2 containing adapter protein GRB 10 interacts with BCR ABL . ^^^ More importantly , we identified the SH 2 containing protein Grb 10 as a new binding partner for Bcr Abl . ^^^ Both Abl and Bcr alone , as well as a kinase defective Bcr Abl , failed to interact with Grb 10 in yeast . ^^^ Using a temperature sensitive Bcr Abl stably overexpressed in hematopoetic cells , we demonstrated that complex formation of Grb 10 with Bcr Abl was kinase activation dependent in vivo . ^^^ Notably , a Bcr Abl mutant protein ( Bcr / 1 242 Abl ) which lacks the ability to interact with Grb 10 partially alleviated IL 3 dependence of Ba / F3 cells , indicating that the Grb10 / Bcr Abl interaction is important for Bcr Abl induced IL 3 independence of Ba / F3 cells . ^^^ |
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| Interacting proteins: Q13322 and P11274 |
Pubmed |
SVM Score :0.0 |
| The RSS dimer was subsequently rearranged in all investigated subclones to an identical J alpha element . ^^^ |
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| Interacting proteins: Q13322 and P11274 |
Pubmed |
SVM Score :0.0 |
| This method was tested on 101 B lineage leukaemias ( 71 childhood B cell precursor acute lymphoblastic leukaemias ( BCP ALL ) and 30 chronic lymphocytic leukaemias ( CLL ) ) . 39 and 22 Kde rearrangements could be readily detected in 30 ( 44 % ) BCP ALL and 22 ( 56 % ) CLL , respectively . 36 % of the Kde rearrangements in BCP ALL and 45 % in CLL were intron recombination signal sequence ( RSS ) Kde rearrangements . ^^^ |
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| Interacting proteins: Q13322 and P11274 |
Pubmed |
SVM Score :0.0 |
| Examples of the use of the RSS 1 . 0 ( RDF Site Summary ) specification together with CML ( Chemical Markup Language ) to create a metadata based alerting service termed CMLRSS for molecular content are presented . ^^^ |
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| Interacting proteins: Q13322 and P11274 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q13322 and P11274 |
Pubmed |
SVM Score :0.0 |
| NA |
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