| Interacting proteins: P11274 and P48729 |
Pubmed |
SVM Score :0.0 |
| Finally , CD 40 mediated signals induce resting B cells to accumulate the CKI , p 21 , while cycling B cells require both BCR and CD 40 mediated signals to maintain increased expression of p 21 . ^^^ |
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| Interacting proteins: P11274 and P48729 |
Pubmed |
SVM Score :0.0 |
| Upon engagement of the B Cell Receptor ( BCR ) of WEHI 231 immature B cells , a drop in c Myc expression is followed by activation of the cyclin dependent kinase inhibitor ( CKI ) p 27 ( Kip 1 ) , which induces growth arrest and apoptosis . ^^^ |
|
| Interacting proteins: P11274 and P48729 |
Pubmed |
SVM Score :0.0 |
| For example , 20 % 30 % of B lineage acute lymphoblastic leukemias ( ALL ) have deletions in the CKI known as INK4a . ^^^ The sorted populations and B lineage ALL cell lines ( BLIN 1 , 2 , 3 , 4 ) were examined for expression of cyclins , CDK , and CKI by reverse transcriptase polymerase chain reaction ( RT PCR ) and Western blotting . ^^^ |
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