| Interacting proteins: Q16778 and P10809 |
Pubmed |
SVM Score :0.0 |
| An 18 kDa plasma membrane associated protein coimmunoprecipitated with hsp 60 and was identified as histone 2B ( H2B ) . ^^^ Hsp 60 physically associated with H2B when both molecules were in their dephospho forms . ^^^ By contrast , PKA catalyzed phosphorylation of both hsp 60 and H2B caused dissociation of H2B from hsp 60 and loss of H2B from the plasma membrane of intact T cells . ^^^ These results suggest that ( 1 ) hsp 60 and H2B can localize in the T cell plasma membrane ; ( 2 ) hsp 60 functions as a molecular chaperone for H2B ; and ( 3 ) PKA catalyzed phosphorylation of both hsp 60 and H2B appears to regulate the attachment of H2B to hsp 60 . ^^^ We propose a model in which phosphorylation / dephosphorylation regulates chaperoning of H2B by hsp 60 in the plasma membrane . . ^^^ |
|
| Interacting proteins: Q16778 and P10809 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q16778 and P10809 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q16778 and P10809 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q16778 and P10809 |
Pubmed |
SVM Score :0.0 |
| NA |
|