| Interacting proteins: Q02218 and P10809 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02218 and P10809 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q02218 and P10809 |
Pubmed |
SVM Score :0.0 |
| Mitochondrial proteins such as E 2 subunits of both pyruvate dehydrogenase and alpha ketoglutarate dehydrogenase , aconitase , heat shock protein 60 , and the cytosolic fatty acid synthase ( alpha subunit ) and glyceraldehyde 3 phosphate dehydrogenase were the major targets . ^^^ |
|
| Interacting proteins: Q02218 and P10809 |
Pubmed |
SVM Score :0.0 |
| Previously , we have identified mitochondrial HSP 70 , HSP 60 , aspartate aminotransferase , and the E 2 and E 3 subunits of the alpha ketoglutarate dehydrogenase ( alphaKGDH ) complex as specific proteins structurally modified during this process . ^^^ |
|
| Interacting proteins: Q02218 and P10809 |
Pubmed |
SVM Score :0.0 |
| TFEC induced cell death is associated with an early covalent modification of specific intramitochondrial proteins ; including aconitase , alpha ketoglutarate dehydrogenase ( KGDH ) subunits , HSP 60 and HSP 70 . ^^^ |
|
| Interacting proteins: Q02218 and P10809 |
Pubmed |
SVM Score :0.0 |
| Tetrafluoroethylcysteine ( TFEC ) , a metabolite of the industrial gas tetrafluoroethylene , can cause both nephrotoxicity and limited hepatotoxicity in animal models , and this is associated with the covalent modification of specific intramitochondrial proteins including heat shock protein 60 ( HSP 60 ) , mitochondrial HSP 70 ( mtHSP 70 ) , aspartate aminotransferase ( AST ) , aconitase , and alpha ketoglutarate dehydrogenase ( alphaKGDH ) . ^^^ |
|
| Interacting proteins: Q02218 and P10809 |
Pubmed |
SVM Score :0.0 |
| Previously , S ( 1 , 1 , 2 , 2 tetrafluoroethyl ) l cysteine ( TFEC ) was shown to mediate cytotoxicity by covalently modifying a well defined group of intramitochondrial proteins including aconitase , alpha ketoglutarate dehydrogenase ( alphaKGDH ) subunits , heat shock protein 60 ( HSP 60 ) and mitochondrial HSP 70 ( mtHSP 70 ) . ^^^ |
|