| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| The purified complex had a specific activity of 1 . 5 2mumol / min mg protein and contained the following partial activities : pyruvate dehydrogenase ( EC 1 . 2 . 4 . 1 ) , dihydrolipoamide transacetylase ( EC 2 . 3 . 1 . 12 ) and dihydrolipoamide dehydrogenase ( EC 1 . 6 . 4 . 3 ) . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| A 20 fold induction of the pyruvate dehydrogenase complex , pyruvate dehydrogenase ( EC 1 . 2 . 4 . 1 ) plus dihydrolipoate S acetyltransferase , ( lipoyltransacetylase ) ( EC 2 . 3 . 1 . 12 ) plus dihydrolipoyl dehydrogenase , NADH : lipoamide oxidoreductase , ( EC 1 . 6 . 4 . 3 ) , from a specific activity of 3 . 5 65 . 0 was observed in mitochondrial extracts during adaptation of Neurospora to glucose from acetate media . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| The oxidation of pyruvate is mediated by the pyruvate dehydrogenase complex ( PDHC ; EC 1 . 2 . 4 . 1 , EC 2 . 3 . 1 . 12 and EC 1 . 6 . 4 . 3 ) whose catalytic activity is influenced by phosphorylation and by product inhibition . 2 Oxoglutarate and 3 hydroxybutyrate are readily utilized by brain mitochondria and inhibit pyruvate oxidation . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| Pyruvate dehydrogenase complex ( PDHC ; EC 1 . 2 . 4 . 1 , EC 2 . 3 . 1 . 12 and EC 1 . 6 . 4 . 3 ) includes 3 catalytically active mitochondrial enzymes involved in the formation of cellular energy through the tricarboxylic acid cycle and in the synthesis of ACh . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| The relation between the activation ( phosphorylation ) state of pyruvate dehydrogenase complex ( PDHC ; EC 1 . 2 . 4 . 1 , EC 2 . 3 . 1 . 12 , and EC 1 . 6 . 4 . 3 ) and the rate of pyruvate oxidation has been examined in isolated , metabolically active , and tightly coupled mitochondria from rat cerebral cortex . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| The activity of the pyruvate dehydrogenase complex ( PDHC ; EC 1 . 2 . 4 . 1 , EC 2 . 3 . 1 . 12 , and EC 1 . 6 . 4 . 3 ) was reduced to about 30 % of control values in histologically unaffected occipital cortex of the brains of patients with Alzheimer ' s disease , as well as in histologically affected frontal cortex . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| The activity of the third TPP dependent enzyme , pyruvate dehydrogenase complex ( EC 1 . 2 . 4 . 1 , EC 2 . 3 . 1 . 12 , EC 1 . 6 . 4 . 3 ) did not change nor did the activity of its activator pyruvate dehydrogenase phosphate phosphatase ( EC 3 . 1 . 3 . 43 ) . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| A method is described to measure directly in rat brain the activity of pyruvate dehydrogenase kinase ( PDHa kinase ; EC 2 . 7 . 1 . 99 ) , which catalyzes the inactivation of pyruvate dehydrogenase complex ( PDHC , EC 1 . 2 . 4 . 1 , EC 2 . 3 . 1 . 12 , and EC 1 . 6 . 4 . 3 ) . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| The peripheral subunit binding domain ( PSBD ) of the dihydrolipoyl acetyltransferase ( E 2 , EC 2 . 3 . 1 . 12 ) binds tightly but mutually exclusively to dihydrolipoyl dehydrogenase ( E 3 , EC 1 . 8 . 1 . 4 ) and pyruvate decarboxylase ( E 1 , EC 1 . 2 . 4 . 1 ) in the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| In this report we demonstrate that sera from patients with PBC also recognize the E 1 component ( pyruvate dehydrogenase , EC 1 . 2 . 4 . 1 ) of PDC . ^^^ |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10515 and P11177 |
Pubmed |
SVM Score :0.0 |
| NA |
|