| Interacting proteins: P10276 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Multiprobe ribonuclease protection assay and real time RT PCR were used to quantitate mRNA levels of steroid receptors , vitamin D receptors ( VDR ) and retinoic acid receptors ( RAR ) and cofactors : amplified in breast cancer 1 , cyclic AMP response element binding protein ( CBP ) , p300 / CBP associated factor , p 300 , nuclear receptor corepressor and silencing mediator of repressed transcription . ^^^ |
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| Interacting proteins: P10276 and Q92831 |
Pubmed |
SVM Score :0.0 |
| METHODS : Multiprobe ribonuclease protection assay and real time reverse transcriptase polymerase chain reaction were used to quantitate mRNA levels of steroid receptors , vitamin D receptor ( VDR ) , retinoic acid receptors ( RAR ) , and cofactors AIB 1 ( amplified in breast cancer 1 ) , CBP ( cyclic adenosine monophosphate response element binding protein ) , pCAF ( p300 / CBP associated factor ) , TIF 2 ( transcription intermediary factor 2 ) , N CoR ( nuclear receptor corepressor ) , and SMRT ( silencing mediator of repressed transcription ) . ^^^ |
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| Interacting proteins: P10276 and Q92831 |
Pubmed |
SVM Score :0.0 |
| Molecular interaction of retinoic acid receptors with coregulators PCAF and RIP 140 . p300 / CBP associating factor ( PCAF ) is a ligand dependent coactivator , whereas receptor interacting protein 140 ( RIP 140 ) is a ligand dependent negative coregulator for retinoic acid ( RA ) receptor ( RAR ) and retinoid 10 receptor ( RXR ) . ^^^ To compare these molecular interactions and to determine the effect of RXR ligands , we focus on PCAF / RAR / RXR complex formation in this study for a comparison to RIP140 / RAR / RXR complex formation . ^^^ BIAcore studies determine the Kd of RAR / RXR association with PCAF as 9 . 35 nM in the presence of RXR ligand AGN 194204 , and 47 . 2 nM in the absence of ligand . ^^^ Cross linking study demonstrates tri molecular complex consisting of one RAR / RXR pair and one PCAF . ^^^ In competition experiments , RIP 140 strongly competes with PCAF for interaction with RAR / RXR both in vitro and in vivo . ^^^ |
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| Interacting proteins: P10276 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P10276 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92831 |
Pubmed |
SVM Score :0.0 |
| NA |
|