| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.51771951 |
| The binding of COUP TF to the DR 8 element synergistically increases the RA dependent RARalpha transactivation function by enhancing the interaction of RARalpha with its coactivator CREB binding protein . 0.51771951^^^ |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| To assess the role of CBP / p300 in all trans retinoic acid ( ATRA ) mediated growth arrest in mammary epithelial cells , two systems were tested : ( 1 ) ATRA resistant MCF 7 cells were transduced with a functional RAR beta 2 ; ( 2 ) normal human mammary epithelial cells ( HMECs ) were transduced with a pan RAR dominant negative , RAR alpha 403 . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| By comparing control arrays from the two cell populations , cAMP response element binding protein ( CBP ) , which is associated with steroid receptor dependent target gene transcription and the oncoprotein , tyrosine kinase T 3 ( TRK T 3 ) , were up regulated whereas retinoic acid receptor alpha ( RARalpha ) was down regulated in multiply passaged cells . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Several nuclear receptor coactivators ( CBP , F SRC 1 , SRC 1 , and RIP 140 ) that interact with other steroid receptors were tested as potential mediators of the N and C terminal interaction of rAR using the mammalian two hybrid system . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Instead , E1A inhibits RAR function by preventing the assembly of CBP nuclear receptor coactivator complexes , revealing differences in required CBP domains for transcriptional activation by RAR and STAT1 . . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Interestingly , however , our results along with previously reported observations suggest that in addition to CBP , there may be other limiting cofactor ( s ) responsible for mutual transrepression of RAR and AP1 . . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| In addition , an RAR associated protein , CREB binding protein ( CBP ) , potentiated the effects of RAR on hSP B promoter activity in H 441 cells . ^^^ These findings support a model in which RAR / retinoid 10 receptor , TTF 1 , coactivators , and CBP form a transcription activation complex in the upstream enhancer region of the hSP B gene . . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Multiprobe ribonuclease protection assay and real time RT PCR were used to quantitate mRNA levels of steroid receptors , vitamin D receptors ( VDR ) and retinoic acid receptors ( RAR ) and cofactors : amplified in breast cancer 1 , cyclic AMP response element binding protein ( CBP ) , p300 / CBP associated factor , p 300 , nuclear receptor corepressor and silencing mediator of repressed transcription . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| METHODS : Multiprobe ribonuclease protection assay and real time reverse transcriptase polymerase chain reaction were used to quantitate mRNA levels of steroid receptors , vitamin D receptor ( VDR ) , retinoic acid receptors ( RAR ) , and cofactors AIB 1 ( amplified in breast cancer 1 ) , CBP ( cyclic adenosine monophosphate response element binding protein ) , pCAF ( p300 / CBP associated factor ) , TIF 2 ( transcription intermediary factor 2 ) , N CoR ( nuclear receptor corepressor ) , and SMRT ( silencing mediator of repressed transcription ) . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| CONCLUSION : The present study proposes a new mechanism by which ER and RAR regulate BRCA 1 mediated DNA repair by means of CBP . . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Interaction of p300 / CBP with E1A completely prevented hPDK 4 gene activation by RXRalpha / RARalpha / RA and TSA . ^^^ |
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| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| These findings support a model in which RAR / retinoid 10 receptor , TTF 1 , and coactivators ( p 160 members and CBP ) form an enhanceosome in the enhancer region of the hSP B gene . . ^^^ |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Inhibition of RAR function in HMECs by DNRAR suppressed expression of CBP / p300 and expression of RARbeta 2 in MCF 7 cells promoted induction of CBP / p300 when cells were treated with 1 . 0 microM all trans retinoic acid ( ATRA ) . ^^^ |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
|