| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| The full length GRIP 1 interacted with the hormone binding domains ( HBDs ) of all five steroid receptors in a hormone dependent manner and also with HBDs of class 2 nuclear receptors , including thyroid receptor alpha , vitamin D receptor , retinoic acid receptor alpha , and retinoid 10 receptor alpha . ^^^ |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| Here we report that , in addition to NID , another region of coactivator GRIP 1 ( amino acids 1011 1121 ) , called the auxiliary NID ( NIDaux ) , is required in vitro and in vivo for efficient interaction with a subset of NRs , including the glucocorticoid receptor ( GR ) , androgen receptor , and retinoic acid receptor alpha . ^^^ |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| RAR coactivators ACTR , SRC 1 , and transcriptional intermediary factor 2 ( TIF 2 ) stimulated human ( h ) SP B promoter activity in a dose dependent fashion in pulmonary adenocarcinoma H 441 cells . ^^^ |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| METHODS : Multiprobe ribonuclease protection assay and real time reverse transcriptase polymerase chain reaction were used to quantitate mRNA levels of steroid receptors , vitamin D receptor ( VDR ) , retinoic acid receptors ( RAR ) , and cofactors AIB 1 ( amplified in breast cancer 1 ) , CBP ( cyclic adenosine monophosphate response element binding protein ) , pCAF ( p300 / CBP associated factor ) , TIF 2 ( transcription intermediary factor 2 ) , N CoR ( nuclear receptor corepressor ) , and SMRT ( silencing mediator of repressed transcription ) . ^^^ |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| GRIP 1 interacts in a hormone dependent manner with the C termini of nuclear hormone receptors such as GRalpha , TRalpha , TRbeta , RARalpha and RXRalpha but not with 5 ErbA . ^^^ |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| TIF 2 mediates the synergy between RARalpha 1 activation functions AF 1 and AF 2 . ^^^ Here we demonstrate that TIF 2 , a p 160 coactivator , is able to bridge the two activation domains of the retinoic acid ( RA ) receptor isotype RARalpha 1 , resulting in synergistic activation of transcription . ^^^ Bridging requires the presence of motifs in region A of RARalpha 1 and in the activation domain AD 1 of TIF 2 . ^^^ |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10276 and Q15596 |
Pubmed |
SVM Score :0.0 |
| NA |
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