| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Treatment of THP 1 cells with soluble LIGHT also caused induction of MMP 9 and interleukin 8 . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Expression of basic fibroblast growth factor , interleukin 8 and MMP 9 did not correlate with outcome . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| We examined the signaling mechanisms that regulate interleukin 8 ( IL 8 ) mediated MMP 9 release from neutrophils . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Interleukin 8 concentrations in the myometrium , decidua , and membranes correlated strongly with the observed MMP 8 and MMP 9 concentrations . . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| The expression of basic fibroblast growth factor , vascular endothelial growth factor / vascular permeability factor ( VEGF / VPF ) , interleukin 8 ( IL 8 ) , and collagenase type 4 ( MMP 2 [ matrix metalloproteinase 2 ] and MMP 9 ) was determined by northern blot analysis , in situ hybridization of messenger RNA , and immunohistochemical analysis . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Interleukin 8 given intradermally concomitantly with pathogenic anti mBP 180 elicited a significant neutrophil recruitment into the skin in gelatinase B deficient mice , but blistering did not occur . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| The expression of epidermal growth factor receptor , E cadherin , type 4 collagenase [ matrix metalloproteinase ( MMP ) 2 and MMP 9 ) , basic fibroblast growth factor , vascular endothelial growth factor / vascular permeability factor , and interleukin 8 was examined by a colorimetric in situ mRNA hybridization technique . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| In this work , we show that endotoxin ( lipopolysaccharide [ LPS ] ) and other inflammatory mediators , such as tumor necrosis factor ( TNF ) , interleukin 8 , and granulocyte colony stimulating factor , induce a rapid ( within 20 min ) release of gelatinase B ( MMP 9 ) zymogen in whole human blood , as determined by gelatin zymography . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Additional experiments showed that interleukin 8 induces the rapid release of the metalloproteinase gelatinase B , concurrent with the mobilization of hematopoietic progenitor cells . ^^^ Because neutrophils express leukocyte function associated antigen 1 and high affinity interleukin 8 receptors , and release gelatinase B upon stimulation with interleukin 8 , we hypothesized that neutrophils are key mediators in interleukin 8 induced stem cell mobilization . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| At 4 h after an intradermal injection of interleukin 8 , numerous PMN were present extravascularly in the dermis in both gelatinase B / and gelatinase B+ / + mice and the myeloperoxidase activities of the skin at the injection sites were indistinguishable between the two types of mice . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| In acute inflammation the contribution of chemokines is hierarchically organised , interleukin 8 ( IL 8 ) and related CXC chemokines inducing a rapid influx of neutrophils in the acute lesions and an instantaneous exocytosis of gelatinase B granules . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Activation of PPARalpha or gamma reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP 1 cells . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| The expression of E cadherin ( related to cell cohesion ) , type 4 collagenase [ matrix metalloproteinase ( MMP ) 2 and MMP 9 , related to invasion ] , and three angiogenic molecules , basic fibroblast growth factor , vascular endothelial growth factor / vascular permeability factor , and interleukin 8 , were examined by a colorimetric in situ mRNA hybridization technique . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Neutrophil gelatinase B potentiates interleukin 8 tenfold by aminoterminal processing , whereas it degrades CTAP 3 , PF 4 , and GRO alpha and leaves RANTES and MCP 2 intact . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| The expression of vascular endothelial growth factor / vascular permeability factor ( VEGF / VPF ) , basic fibroblast growth factor ( bFGF ) , E cadherin , type 4 collagenase , matrix metalloproteinase ( MMP 2 and MMP 9 ) , and interleukin 8 ( IL 8 ) was examined by a colorimetric in situ mRNA hybridization technique . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Although moderately increased levels of interleukin 8 , MCP 1 , or MMP 9 were also present after fucoidan treatment , studies in gene ablated mice ( GCSFR ( / ) , MCP 1 ( / ) , or MMP 9 ( / ) ) and the use of metalloprotease inhibitors do not support their involvement in the concurrent mobilization . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| In arthritic diseases , neutrophils undergo great chemoattraction to the synovium , are activated by interleukin 8 , and are stimulated to release gelatinase B in vivo . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| For example , the chemokine interleukin 8 acts as a fast secretagogue of gelatinase B in granulocytes and is increased in the synovial fluid of arthritis patients and may locally recruit and activate neutrophils . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| In vitro , SDF 1alpha ( 500 ng / mL ) reduced both unstimulated and endotoxin / mitogen stimulated mRNA and protein levels of monocyte chemoattractant protein 1 , interleukin 8 , matrix metalloproteinase 9 , and tissue factor while increasing tissue inhibitor of metalloproteinases 1 in PBMC from patients with unstable angina . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Simultaneous induction of matrix metalloproteinase 9 and interleukin 8 by all trans retinoic acid in human PL 21 and NB 4 myeloid leukaemia cells . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Specific transcript RT PCR analysis showed increased production of interleukin 1beta ( IL 1beta ) , interleukin 6 ( IL 6 ) , interleukin 8 ( IL 8 ) , and matrix metalloproteinase 9 ( MMP 9 , gelatinase B ) mRNA levels in response to SM exposure . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Interferon ( IFN ) alpha and beta inhibit angiogenesis through downregulation of interleukin 8 , matrix metalloproteinase 9 , and basic fibroblast growth factor . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Fifty five primary and metastatic FIGO stage 3 4 ovarian carcinomas were analyzed for the expression of alpha 5 and beta 1 integrin subunits , the matrix metalloproteinases MMP 2 , MMP 9 , and MT 1 MMP , the MMP inhibitor TIMP 2 , vascular endothelial growth factor ( VEGF ) , basic fibroblast growth factor ( bFGF ) , interleukin 8 ( IL 8 ) , PEA 3 and Ets 1 using mRNA in situ hybridization . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| The interleukin 8 mediated neutrophil influx in allergic bronchopulmonary aspergillosis may induce lung damage via release of matrix metalloproteinase 9 , potentially leading to bronchiectasis . . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| We determined bone marrow ( BM ) and peripheral blood ( PB ) plasma levels of SDF 1 , together with CXC chemokine receptor 4 ( CXCR 4 ) expression on CD34+ cells , and interleukin 8 ( IL 8 ) and MMP 9 in 55 patients mobilized for autologous PB transplantation compared with 10 normal BM and PB samples . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Gelatinase zymography showed matrix metalloproteinase 9 expression in the ipsilateral striatum after interleukin 8 injection . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Matrix metalloproteinases ( MMPs ) , such as gelatinase A / MMP 2 and gelatinase B / MMP 9 , are known to process the aminoterminal end of various chemokines , including interleukin 8 ( IL 8 / CXCL 8 ) and monocyte chemotactic protein 3 ( MCP 3 / CXCL 7 ) . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Macrophage migration inhibitory factor enhances neoplastic cell invasion by inducing the expression of matrix metalloproteinase 9 and interleukin 8 in nasopharyngeal carcinoma cell lines . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| This study was designed to investigate whether the macrophage migration inhibitory factor ( MIF ) can affect the expression of matrix metalloproteinase 2 , 9 ( MMP 2 , MMP 9 ) and interleukin 8 ( IL 8 ) in nasopharyngeal carcinoma ( NPC ) cell strains . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Furthermore , in these cells , PMV stimulated mRNA expression for angiogenic factors such as MMP 9 , vascular endothelial growth factor , interleukin 8 and hepatocyte growth factor , as well as adhesion to fibrinogen and human umbilical vein endothelial cells . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Northern blot analyses confirmed some gene expression such as interleukin 6 , interleukin 8 , and matrix metalloproteinase 9 . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Inflammatory markers ( tumour necrosis factor alpha , interleukin 8 , polymorphonuclear elastase ) , fibrinolytic system variables ( tissue plasminogen activator ( PA ) , urokinase PA ( u PA ) , plasminogen activation inhibitor ( PAI ) 1 , PAI 2 ) , and several MMPs ( MMP 1 , MMP 2 , MMP 8 , MMP 9 ) and TIMPs ( TIMP 1 , TIMP 2 ) were determined by ELISA in plasma and pleural fluid . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Measures of airway inflammation from induced sputum included cell counts and differentials , interleukin 8 ( IL 8 ) , neutrophil elastase , MMP 9 , and TIMP 1 . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Protein kinase C , phosphatiolylinositol 3 kinase and calcium uptake channels all play a role in MMP 9 secretion , whereas neither tumour necrosis factor alpha , interleukin 8 , nor interleukin 1beta autocrine stimulation appear to contribute . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| TNF alpha elicited a 3 4 fold increase of monocyte attracting protein 1 ( MCP 1 ) and interleukin 8 ( IL 8 ) as compared to the control value , matrix metalloproteinase 9 ( MMP 9 ) and vascular endothelial growth factor ( VEGF ) were enhanced by 30 to 40 % . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| RESULTS : The 22 genes that were up regulated in the 21 F 2 samples relative to the 18 F 1 samples mainly encoded genes involved in cytoskeleton ( KRT 19 and SCG 10 ) , growth factors / cytokines ( CXCL 6 , interleukin 8 [ IL 8 ] , IL1A , IL 2 , and CXCL 10 ) , or growth factor receptors ( CCR 2 , CXCR 3 , and CXCR 4 ) , or were involved in extracellular matrix production ( COL1A1 , CHI3L , and SPP 1 ) , in extracellular matrix remodeling ( TIMP 1 , MMP 7 , and MMP 9 ) , and in cell junction ( ITGA 2 and CLDN 4 ) . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Plaques of patients with TIA and stroke showed significantly higher activity levels of MMP 8 and MMP 9 and higher levels of interleukin 8 compared with asymptomatic and AFX patients . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| In the joints of rheumatoid arthritis patients , CXC chemokines , such as interleukin 8 / CXCL8 , recruit and activate neutrophils to secrete prestored neutrophil collagenase / MMP 8 and gelatinase B / MMP 9 . ^^^ Gelatinase B potentiates interleukin 8 at least tenfold and thus enhances neutrophil and lymphocyte influxes to the joints . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| In sputum , the present authors measured cell counts , the soluble and cellular iron concentration , and levels of interleukin 8 , tumour necrosis factor alpha , myeloperoxidase , matrix metalloproteinase 9 , immunoglobulin ( Ig ) A , alpha ( 2 ) macroglobulin and unsaturated iron binding capacity . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Cellular expression of matrix metalloproteinase 9 and two major angiogenic factors , vascular endothelial growth factor and interleukin 8 , were also significantly decreased in cell lines with Cap 43 overexpression as compared with their parental counterparts . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Although chemokines bind to G protein linked receptors , CXCL 8 , CXCL 10 , CCL 2 , and CCL 5 did not stimulate monocyte MMP 9 secretion . ^^^ |
|
| Interacting proteins: P10145 and P14780 |
Pubmed |
SVM Score :0.0 |
| Selected relevant genes ( CCL 20 , CCL 2 , CXCL 8 , CXCR 4 , L selectin , GM CSF , IL1B , MMP 9 , UPA , and SPP1 / OPN ) were found up regulated also in clinical samples of PTC , particularly those characterized by RET / PTC activation , local extrathyroid spread , and lymph node metastases , when compared with normal thyroid tissue or follicular thyroid carcinoma . ^^^ |
|