| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| The granzyme B inhibitor , protease inhibitor 9 , is mainly expressed by dendritic cells and at immune privileged sites . ^^^ |
|
| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| Expression of the granzyme B inhibitor , protease inhibitor 9 , by tumor cells in patients with non Hodgkin and Hodgkin lymphoma : a novel protective mechanism for tumor cells to circumvent the immune system . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| Actual execution of apoptosis depends on proper functioning of effector caspases , particularly caspase 3 , and on the expression levels of apoptosis regulating proteins , including Bcl 2 and the recently identified granzyme B specific protease inhibitor 9 ( PI 9 ) . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| In addition , hepatic NK cells and sinusoidal endothelial cells strongly expressed the granzyme B inhibitor , protease inhibitor 9 ( PI 9 ) / serine PI 6 ( SPI 6 ) , and P 815 cells and hepatocytes were negative . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| Here , we investigated in pretreatment biopsies of 70 patients with DLBCL whether numbers of activated cytotoxic T lymphocytes ( CTLs ) , as determined by the percentage of CD 3 positive lymphocytes with granzyme B ( GrB ) expression , have similar prognostic value as found earlier in Hodgkin ' s lymphoma and anaplastic large cell lymphoma and whether loss of major histocompatibility complex ( MHC ) 1 molecules or expression of the GrB antagonist protease inhibitor 9 ( PI 9 ) may explain immune escape from CTL mediated cell death . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| Serine protease inhibitor 6 ( SPI 6 ) , also called Serpinb 9 , inhibits granzyme B and thus may provide a method for delaying apoptotic cell death in dendritic cells . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| Protease inhibitor 9 ( PI 9 ) , an intracellular serpin that inhibits granzyme B , is known to protect cells from the action of cytotoxic T lymphocytes . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| Furthermore , gastric cancer cells cultured with IL 18 showed an increased expression of a granzyme B inhibitor , protease inhibitor 9 . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| Tumor cells can evade the immune system , for example through interference with antigen presentation by down regulation of MHC molecules or expressing proteins interfering with cytotoxic lymphocyte induced apoptosis like the granzyme B antagonist protease inhibitor 9 ( PI 9 ) . ^^^ |
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| Interacting proteins: P10144 and P50453 |
Pubmed |
SVM Score :0.0 |
| The granzyme B inhibitor SERPINB 9 ( protease inhibitor 9 ) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation . ^^^ SERPINB 9 is the only known human intracellular inhibitor of granzyme B ( GrB ) , the effector molecule in immunity against cytomegalovirus ( CMV ) and in renal allograft rejection . ^^^ |
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