| Interacting proteins: P10109 and P19099 |
Pubmed |
SVM Score :0.0 |
| The effect of Adx 1 108 on the product patterns of bovine CYP11B1 , human CYP11B1 and human CYP11B2 was confirmed in COS 1 cells by cotransfection of CYP11B and Adx containing expression vectors . ^^^ It could be shown that Adx 1 108 enhances the formation of aldosterone by bovine CYP11B1 and by human CYP11B2 , and stimulates the production of corticosterone by bovine CYP11B1 and human CYP11B1 and CYP11B2 also . . ^^^ |
|
| Interacting proteins: P10109 and P19099 |
Pubmed |
SVM Score :0.0 |
| Adrenodoxin ( Adx ) , a [ 2Fe 2S ] vertebrate type ferredoxin , transfers electrons from the NADPH dependent flavoprotein Adx reductase ( AdR ) to mitochondrial cytochrome P 450 enzymes of the CYP11A and CYP11B families , which catalyze key reactions in steroid hormone biosynthesis . ^^^ |
|
| Interacting proteins: P10109 and P19099 |
Pubmed |
SVM Score :0.0 |
| We tested the hypothesis that reducing aldosterone by inhibiting CYP11B2 or by adrenalectomy ( ADX ) may ameliorate organ damage . ^^^ METHODS AND RESULTS : We investigated the effect of the CYP11B2 inhibitor FAD 286 , losartan , and the consequences of ADX in transgenic rats overexpressing both the human renin and angiotensinogen genes ( dTGR ) . dTGR ADX received dexamethasone and 1 % salt . ^^^ |
|
| Interacting proteins: P10109 and P19099 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19099 and P10109 |
Pubmed |
SVM Score :0.0 |
| The effect of Adx 1 108 on the product patterns of bovine CYP11B1 , human CYP11B1 and human CYP11B2 was confirmed in COS 1 cells by cotransfection of CYP11B and Adx containing expression vectors . ^^^ |
|
| Interacting proteins: P19099 and P10109 |
Pubmed |
SVM Score :0.0 |
| Adrenodoxin ( Adx ) , a [ 2Fe 2S ] vertebrate type ferredoxin , transfers electrons from the NADPH dependent flavoprotein Adx reductase ( AdR ) to mitochondrial cytochrome P 450 enzymes of the CYP11A and CYP11B families , which catalyze key reactions in steroid hormone biosynthesis . ^^^ |
|
| Interacting proteins: P19099 and P10109 |
Pubmed |
SVM Score :0.0 |
| We tested the hypothesis that reducing aldosterone by inhibiting CYP11B2 or by adrenalectomy ( ADX ) may ameliorate organ damage . ^^^ METHODS AND RESULTS : We investigated the effect of the CYP11B2 inhibitor FAD 286 , losartan , and the consequences of ADX in transgenic rats overexpressing both the human renin and angiotensinogen genes ( dTGR ) . dTGR ADX received dexamethasone and 1 % salt . ^^^ |
|
| Interacting proteins: P19099 and P10109 |
Pubmed |
SVM Score :0.0 |
| NA |
|