| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| C 33 antigen recognized by monoclonal antibodies inhibitory to human T cell leukemia virus type 1 induced syncytium formation is a member of a new family of transmembrane proteins including CD 9 , CD 37 , CD 53 , and CD 63 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Mapping of the genes for four members of the transmembrane 4 superfamily : mouse Cd 9 , Cd 63 , Cd 81 , and Cd 82 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| The CD 82 Ag , which belongs to the new tetra span transmembrane family ( CD 9 , CD 37 , CD 53 , CD 63 , and CD 81 ( TAPA 1 ) ) , has been identified originally in our laboratory for its enhanced expression on three LAK susceptible cell lines , and has been characterized as an activation / differentiation marker of mononuclear cells . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| The genomic organization of CD 82 is quite similar to that of three other TM4SF members whose genomic structures were described , i . e . , Tapa 1 ( CD 81 ) , CD 53 , and CD 63 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| CD 81 ( TAPA 1 ) and CD 82 ( R 2 ) are new members of the tetra spans family of transmembrane proteins , which include CD 9 , CD 37 , CD 53 and CD 63 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Transmembrane 4 superfamily proteins CD 81 ( TAPA 1 ) , CD 82 , CD 63 , and CD 53 specifically associated with integrin alpha 4 beta 1 ( CD49d / CD29 ) . ^^^ Abs to other members of the transmembrane 4 superfamily , including CD 53 , CD 63 , and CD 82 , also coprecipitated alpha 4 beta 1 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| CD 9 , CD 63 , CD 81 , and CD 82 are components of a surface tetraspan network connected to HLA DR and VLA integrins . ^^^ CD 9 , CD 63 , CD 81 , and CD 82 are glycoproteins of unknown function which belong to the tetraspan superfamily . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| A brief overview indicates that some tetraspanins are found in virtually all tissues ( CD 81 , CD 82 , CD 9 , CD 63 ) , whereas others are highly restricted , such as CD 37 ( B cells ) or CD 53 ( lymphoid and myeloid cells ) . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| The specificity of this interaction is demonstrated by the fact that other tetraspans , CD 63 , CD 81 , and CD 82 , do not associate with pre beta 1 , and CD 9 does not associate with immature human histocompatibility leukocyte antigen class 1 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| CD 9 , CD 53 , CD 63 , CD 81 , and CD 82 ) . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Expression of tetra spans transmembrane family ( CD 9 , CD 37 , CD 53 , CD 63 , CD 81 and CD 82 ) in normal and neoplastic human keratinocytes : an association of CD 9 with alpha 3 beta 1 integrin . ^^^ Tetra spans transmembrane family ( TSTF ) members ( CD 9 , CD 37 , CD 53 , CD 63 , CD 81 and CD 82 ) have potent effects on cell growth , motility and adhesion in various cells . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| The tetraspanin superfamily ( or TM4SF ) includes CD 81 , CD 9 , CD 37 , CD 53 , CD 63 , CD 82 , CD 151 , and an increasing number of additional proteins . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| In this study , we show that exosomes are enriched in the co stimulatory molecule CD 86 and in several tetraspan proteins , including CD 37 , CD 53 , CD 63 , CD 81 , and CD 82 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| There are five antigens which are detected in 90 % of cell lines at high levels , CD 53 , CD 81 , CD 63 , SAS and CD 82 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Similar experiments showed CD 63 , another tetraspan protein found in MIICs , also associates with these molecules in the compartment and that CD 82 and CD 63 associate with each other . ^^^ Preclearing experiments demonstrated that both CD 82 and CD 63 form complexes with DM associated class 2 and DM associated DO . ^^^ The ability of CD 82 and CD 63 to form complexes with class 2 , DM , and DO in MIICs suggests that the tetraspan proteins may play an important role in the late stages of MHC class 2 maturation . . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Foreskin MC were also recognized by MoAb to CD 47 , CD 48 , CD49d , CD 53 , CD 60 , CD 63 , CD 81 , CD 82 , CD 84 , CD 87 , CD 92 , CD 97 , CD 98 , and CD 99 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| CD 81 , a molecule with 4 transmembrane domains , member of the tetraspan superfamily , is engaged , together with other tetraspans such as CD 9 , CD 53 , CD 63 , and CD 82 , in multimolecular complexes containing beta 1 integrins and major histocompatibility complex antigens . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| In this study we show that another classical mild detergent , digitonin , dissociated most of these associated molecules , including integrins , from the tetraspans CD 9 , CD 37 , CD 53 , CD 63 , CD 82 , Co 029 , Talla 1 and NAG 2 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| The authors characterized immunohistologically the localization of six members of TSTF ( CD 9 , CD 37 , CD 53 , CD 63 , CD 81 , and CD 82 ) in the normal epithelium from esophagus to colon . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Double immunofluorescence staining showed that various TM4SF proteins , including CD 9 , CD 63 , CD 81 , CD 82 , and CD 151 are colocalized within dot like structures that are particularly abundant at the cell periphery . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| There is a correlation between invasive capability and changes in the expression of some proteins that are clustered in focal adhesion sites , as FAK , CD 82 , CD 9 or CD 63 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Immunoprecipitation experiments revealed that not only CD 9 but also other TM 4 proteins including CD 63 , CD 81 , and CD 82 associate with proHB EGF on the cell surface . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| CD 37 is a membrane protein of the tetraspanin superfamily , which includes CD 9 , CD 53 , CD 63 , CD 81 , and CD 82 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| PSG 17 did not bind to cells transfected with CD 53 , CD 63 , CD 81 , CD 82 , or CD 151 , suggesting that PSG 17 CD9 binding is a specific interaction . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| All tetraspanins studied , CD 9 , CD 37 , CD 53 , CD 63 , CD 81 , CD 82 and CD 151 , were found to incorporate [ 3H ] palmitate . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| To this end , MHC molecules become incorporated into two types of membrane microdomains : ( 1 ) cholesterol and glycosphingolipid enriched domains , denoted lipid rafts , that preconcentrate MHC class 2 molecules ; and ( 2 ) microdomains made up of tetraspan proteins , such as CD 9 , CD 63 , CD 81 or CD 82 , that mediate enrichment of MHC class 2 molecules loaded with a select set of peptides . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Here we screened 30 lung cancer cell lines for expression of tetraspanins , CD 9 , CD 63 , CD 81 , CD 82 , CD 151 , and NAG 2 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| We describe the exact quantification of mRNAs coding for the tetraspanins CD 9 , CD 63 , CD 82 and CD 151 expressed by mammary carcinoma derived cell lines that were classified as invasive or non invasive according to their ability to penetrate collagen fibroblast gels in vitro . ^^^ The mean of beta 2 microglobulin normalized expression of CD 9 was about 10 fold higher than the mean calculated for CD 63 and about 20 fold higher than expression of CD 82 and CD 151 . ^^^ Grouping of cell lines in relation to threshold values of expression resulted in significant correlations for CD 63 ( Fisher ' s exact test p=0 . 004 ) and CD 151 ( p=0 . 02 ) but not for CD 82 ( p=0 . 065 ) and CD 9 ( p=0 . 168 ) . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Pretreatment of primary macrophages with anti CD 63 MAb , but not MAbs to other macrophage cell surface tetraspanins ( CD 9 , CD 81 , and CD 82 ) , was shown to inhibit infection by several R 5 and dualtropic strains , but not by X 4 isolates . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| We show that CD 63 , CD 9 , CD 81 , CD 82 , and CD 151 are present in immature DCs . ^^^ Whereas CD 9 and CD 81 are mostly expressed at the cell surface , CD 63 and CD 82 are also located in intracellular organelles . ^^^ Mabs against CD 9 , CD 63 , CD 81 , and CD 82 enhanced by 50 % the migration induced by the chemokines macrophage inflammatory protein 5 ( MIP 5 ) and MIP 1alpha . ^^^ Concomitantly , Mabs against CD 63 and CD 82 diminished the surface expression of CD 29 , CD11b , CD 18 , and alpha 5 integrins . ^^^ These results suggest that CD 9 , CD 63 , CD 81 , and CD 82 could play a role in modulating the interactions between immature DCs and their environment , slowing their migratory ability . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Membranal and cytoplasmic expression of CD 9 , CD 53 , CD 63 , CD 81 , CD 82 and CD 151 in polymorphonuclears ( PMN ) , monocytes , B and T lymphocytes was assessed using flow cytometry . ^^^ Results suggested that for normal PBL , PMN are distinguished by dominant cytoplasmic CD 63 ; monocytes and B cells prevailingly express CD 53 ; CD 82 is primarily expressed on T cell membranes . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| CD 82 , and CD 63 in thyroid cancer . ^^^ CD 82 ( KAI 1 ) and CD 63 ( ME 491 ) are highly glycosylated proteins which belong to the transmembrane 4 superfamily ( TM4SF ) . ^^^ CD 82 has been implicated as a possible prostate cancer metastasis suppressor gene , whereas CD 63 is involved in the progression of human melanoma cancer . ^^^ Down regulation of both CD 82 and CD 63 expression has been associated with the metastatic potential of several solid tumors . ^^^ Currently , information is lacking on the role of CD 82 and CD 63 during thyroid carcinogenesis . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Our results show that HACs express surface molecules belonging to different categories : integrins and other adhesion molecules ( CD49a , CD49b , CD49c , CD49e , CD49f , CD51 / 61 , CD 54 , CD 106 , CD 166 , CD 58 , CD 44 ) , tetraspanins ( CD 9 , CD 63 , CD 81 , CD 82 , CD 151 ) , receptors ( CD 105 , CD 119 , CD 130 , CD140a , CD 221 , CD 95 , CD120a , CD 71 , CD 14 ) , ectoenzymes ( CD 10 , CD 26 ) , and other surface molecules ( CD 90 , CD 99 ) . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Immunofluorescence microscopy indicates that the virus containing compartment in mature DCs ( mDCs ) co labels for the tetraspanins CD 81 , CD 82 , and CD 9 but contains little CD 63 or LAMP 1 . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| Here , we reveal the presence of tetraspanin enriched microdomains ( TEMs ) containing the tetraspanins CD 9 , CD 63 , CD 81 , and CD 82 at the plasma membrane . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| In this study , we investigated the relationships between these three genes , MRP 1 , KAI 1 , and ME 491 , in patients with non small cell lung cancers ( NSCLCs ) . ^^^ Moreover , we assessed the prognostic value of evaluating the expressions of MRP 1 , KAI 1 , and ME 491 simultaneously in NSCLCs . ^^^ Using a quantitative reverse transcriptase polymerase chain reaction ( RT PCR ) analysis , we studied the expression of MRP 1 , KAI 1 , and ME 491 genes in these patients . ^^^ |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08962 and P27701 |
Pubmed |
SVM Score :0.0 |
| NA |
|