| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| We first demonstrate that a 187 bp domain ( 424 to 237 bp ) behaves as a negative region when placed upstream either of the NF kappa B binding site of vimentin or of a heterologous enhancer such as that present in the desmin gene promoter . ^^^ |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| We first demonstrate that the factor NF kappa B binds to the vimentin promoter . ^^^ Specific antibodies and competition experiments between the NF kappa B binding site in the interleukin 2R alpha and HIV 1 promoters and the vimentin promoter show that the three sites have identical affinity for the factor . ^^^ |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| Our results also suggest that NFkB site on the vimentin promoter may act as a positive regulatory element for the transcription of vimentin . ^^^ |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Cisplatin treated rats presented a transitory increase in plasma creatinine levels , tubular cell necrosis and increased immunostaining for vimentin , alpha SM actin , fibronectin , ED 1 , NF kappaB , and p JNK in the renal cortex and outer medulla . ^^^ |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| Vimentin is a member of the intermediate filament family , and the NF kappaB binding site is located in the human vimentin promoter . ^^^ To gain insight into the role of NF kappaB in the regulation of the vimentin gene during 12 O tetradecanoylphorbol 13 acetate ( TPA ) dependent differentiation of HL 60 cells , the effect of pyrrolidine dithiocarbamete ( PDTC ) has been investigated using Northern blot hybridization and DNA mobility shift assay . ^^^ Taken together , these results suggest that NF kappaB may be an essential transacting factor for transcriptional repression of the vimentin gene by PDTC during TPA dependent differentiation of HL 60 cells . . ^^^ |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| Compared with control cells , rel 3983D displayed increased NF kappaB binding and higher levels of the NF kappaB transactivating subunits c Rel , RelA , and RelB , which seemed functional as judged by induction of c Myc and vimentin , products of two NF kappaB target genes . ^^^ |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19838 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|