| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| LoVo / Dx displayed a less differentiated phenotype as assessed by morphology , in vitro growth and altered or increased expression of markers such as desmoplakin and vimentin respectively , and disappearance of mucin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| The predominance of vimentin and the additional expression of cytokeratin subtypes 8 and 18 , as well as the negative staining for epithelial membrane antigen , accorded with results previously reported , for ovarian granulosa cell tumours ; the lack of expression of desmoplakin , however , was a distinctive feature . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| In cell culture , the decidual stromal cells rapidly acquired typical fibroblastoid appearance with abundant arrays of vimentin filaments while the cytokeratin positive epithelial cells , occasionally found in typical epithelioid colonies , lacked vimentin positivity and showed desmoplakin positivity . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Plakoglobin , a plaque protein common to desmosomes and the zonula adhaerens exists in RPE cells of all species , whereas desmoplakin and desmoglein have been identified only in RPE desmosomes of frogs and cows , including bovine RPE cell cultures in which cytokeratins have disappeared and vimentin IFs are the only IFs present . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| In contrast , cells in sparse monolayers had high levels of the vimentin type intermediate filaments , but very low levels of cytokeratins and desmoplakin 1 . ^^^ By treating cells with TPA , intercellular junctions were rapidly disrupted and expression of cytokeratin and desmoplakin was dramatically reduced ; however , vimentin expression was not affected . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| The expression of GFAP , S 100 , NSE , vimentin , cytokeratin , fibronectin and desmoplakin was investigated . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| The intermediate filament ( IF ) system of the various cells of human , pig and rat ovaries was studied by electron microscopy , by immunolocalization using antibodies to cytokeratins , vimentin , desmin and desmoplakin , and by two dimensional gel electrophoresis of cytoskeletal proteins from microdissected tissue samples . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| We consider this unusual combination , i . e . , vimentin IF and desmoplakin plaques , to be a diagnostic feature for meningiomas , and we propose that the cytoskeletal property be used in differential diagnosis of intracranial tumors . . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Changes in cytokeratin , vimentin and desmoplakin distribution during the repair of irradiation induced lung injury in adult rats . ^^^ The expression of cytokeratins , desmoplakin and vimentin has been studied immunohistochemically in the rat lung injured by 10 irradiation using 14 well characterized monoclonal antibodies . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Functional analysis of desmoplakin domains : specification of the interaction with keratin versus vimentin intermediate filament networks . ^^^ We previously demonstrated that truncated desmoplakin 1 ( DP 1 ) molecules containing the carboxyl terminus specifically coalign with and disrupt both keratin and vimentin intermediate filament ( IF ) networks when overexpressed in tissue culture cells ( Stappenbeck , T . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemically , most of the tumour cells stained positive for epithelial membrane antigen and vimentin , but failed to stain for S 100 protein , neurofilament , desmoplakin , and CD 34 . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Vimentin was still present in mesangial like cells , but the proximal , distal , and collecting tubule cells contained uniform networks of cytokeratins K 8 K18 and desmoplakin 1 and 2 around the cell peripheries . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| In confluent cells vimentin forms peripheral filaments which attach to the cell membrane in areas at desmoplakin localization . ^^^ These data suggest that desmoplakin may participate in the molecular organization of interendothelial junctions by interacting with VE cadherin and promoting vimentin anchorage . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Upon loss of cell polarity in low calcium medium , plectin redistributed to a cytoplasmic vimentin and cytokeratin related network , clearly distinct from diffusely distributed fodrin and internalised desmoplakin structures . ^^^ Furthermore , unlike cytokeratins and vimentin , desmoplakin and fodrin did not associate with plectin attached to magnetic beads in cell lysates of unpolarised cells , while all proteins formed a stable complex in polarised cells . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Immunocytochemical studies revealed that the cells express desmoplakin , vimentin , epithelial membrane antigen , fibronectin and actin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| The tumour cells stain positively for vimentin and EMA , and for CD 34 in a number of cases , but lack positivity for S 100 protein , neurofilament and desmoplakin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Perineurioma is composed of elongated bipolar spindle shaped tumour cells which are arranged in storiform , whorled , linear or lamellated growth patterns , The tumour cells stain positively for vimentin and EMA , and for CD 34 in a number of cases , but lack positivity for S 100 protein , neurofilament and desmoplakin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Cells were harvested after the first and fifth passages for analysis of vimentin and desmoplakin expression ( characteristic of human meningeal cells ) , cellular proliferation , density at confluence ( a measure of cellular contact inhibition ) , and alkaline phosphatase production . ^^^ The results indicate that suture derived dural cells can be established and that these cells coexpress vimentin and desmoplakin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Squamous cell carcinoma lines engineered to express constitutively active Akt underwent EMT , characterized by down regulation of the epithelial markers desmoplakin , E cadherin , and beta catenin and up regulation of the mesenchymal marker vimentin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| The cells resulting from this transdifferentiation showed a pronounced and stable fibroblastic phenotype with spindle like morphology , homogeneous high expression of vimentin , N cadherin , and integrin alpha 5 as well as loss of E cadherin and desmoplakin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| We have confirmed the meningothelial origin of these cell lines by assessing expression of vimentin and desmoplakin , characteristic markers for meningiomas . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Light and electron microscopical observations revealed that DP polypeptides including the 90 kDa carboxyl terminal globular domain of DPI specifically colocalized with and ultimately resulted in the complete disruption of keratin and vimentin IF . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| The 14 classic chordomas showed the following pattern of antigen expression ( percent of tumors positive ) : epithelial membrane antigen ( EMA ) 100 % , AE 1 / 3 ( a `` cocktail ' ' of monoclonal antibodies directed against low and high molecular weight epidermal cytokeratins ) 100 % , DP keratin ( DPK ) 100 % , vimentin 100 % , S 100 86 % , neuron specific enolase ( NSE ) 100 % , carcinoembryonic antigen ( CEA ) 57 % , and HMB 45 ( an anti melanoma associated antibody ) 57 % . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Ectopically expressed polypeptides including the C terminus of DP 1 specifically align with keratin and vimentin IF in cultured cells , whereas those lacking this domain do not align with IF . ^^^ The last 68 amino acids of DP are required for alignment along keratin but not vimentin IF , and residues 48 68 from the C terminal end are critical for this interaction . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Our results confirm the ability of the DP COOH terminus ( DPCT ) to interact with at least two regions of the head domain of the type 2 epidermal keratin K 1 and also demonstrate that DPCT can interact with the type 3 IF family members , vimentin and desmin , as well as simple epithelial keratins . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| In contrast , the C subdomain with the COOH terminal extremity of DP interacts with K5 / K14 and K8 / K18 , and its linker region is able to associate with K8 / K18 and vimentin . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| The data suggest that carbonic anhydrase expression in astrocytes is an acute response to injury and that vimentin can be detected in astrocytes , as well as inflammatory cells , as early as 16 dpi . . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| Increased expression of genes encoding glial fibrillary acidic protein , vimentin , complement component 1q ( alpha and beta polypeptides ) , cathepsin D , clusterin and cystatin C was evident in the hippocampus from 170 days after inoculation ( dpi ) , with expression increasing thereafter to terminal disease ( 225 235 dpi ) . ^^^ |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15924 and P08670 |
Pubmed |
SVM Score :0.0 |
| NA |
|